High Volume Brown Discharge from Right Nipple Duct
A 22-year-old transgender woman, who has been undergoing hormone replacement therapy (HRT) for just over a year, reports experiencing reddish-brown discharge from one duct in her right nipple for about a month. Initially, a visit to her healthcare provider suggested that the discharge was likely a result of minor irritation or a slight injury. However, the situation has not improved; yesterday, applying even slight pressure resulted in a considerable amount of brown fluid being expelled from the duct, running down her chest. The consistency reminded her of aged blood or oxidized liquid, marking a significant increase from the previously observed small droplets. Additionally, she noted a small lump adjacent to the duct (slightly off-center from the nipple) that has diminished following the drainage, but she continues to notice brown discharge whenever pressure is applied. There are no signs of spontaneous leakage, pain, redness, or alterations in the skin of the nipple, and there is no family history of breast cancer. The left breast and nipple appear normal, although they are somewhat more tender. She is contemplating requesting a breast ultrasound and is eager for insights regarding the possible causes of this condition and whether it requires immediate attention.
Answers (1)

7/14/2025, 1:01:50 PM
OpenHealth AI
It's understandable to be concerned about reddish-brown discharge from the nipple, especially when it has increased in volume and is accompanied by changes in your breast. Let's break this down:
Main Points:
- The discharge may be related to hormonal changes or minor duct issues.
- A breast ultrasound could help clarify the situation and rule out any serious concerns.
Explanation:
The reddish-brown discharge you’re experiencing can arise from several factors, including hormonal influences from Hormone Replacement Therapy (HRT), which can affect breast tissue and ducts. It may also be linked to a benign condition, such as a clogged duct or duct ectasia, particularly if you have observed a lump that improved after drainage. The discharge resembling aged blood suggests that it might be old blood that has pooled in the duct.
Given that there is no pain, redness, or significant skin changes, this might indicate a less urgent issue, but the persistence and increase in volume warrant careful monitoring and further investigation.
Next Steps:
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Seek Imaging (Ultrasound): Request a breast ultrasound as this can help visualize any abnormalities in the breast tissue or duct system. This is a crucial step to ensure there are no underlying issues.
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Monitor Symptoms: Keep an eye on any changes in the discharge, such as color, consistency, or the presence of pain. Document any new symptoms as they arise.
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Gentle Management: Avoid applying excessive pressure to the affected area to prevent further irritation or injury.
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Consult with Your Provider: If symptoms persist or worsen (e.g., increased lump size, new lumps, significant pain, or changes in surrounding skin), consider following up with your healthcare provider to discuss potential interventions, including the possibility of a diagnostic workup.
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Educate Yourself: Learn about benign breast conditions and the effects of HRT on breast tissue to better understand what you might be experiencing.
If you have any further questions or need detailed information about specific results from the ultrasound, don’t hesitate to reach out. Your health and comfort are important.
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