Understanding Liver Function Tests
Greetings! I’m a 28-year-old woman, weighing 200 pounds and standing 5’8”, and I'm a year postpartum from having twins. I've been prescribed metformin for PCOS and Diclofenac for my back arthritis. I do not smoke or consume alcohol. Ever since reaching the six-month mark of my pregnancy, my liver enzyme levels have elevated. Medical professionals have suggested that I have non-alcoholic fatty liver disease related to my pregnancy, assuring me that it will resolve on its own. This condition appears to be the only aspect of my lab results that is concerning. Although some of my enzyme levels remain elevated, they have decreased recently. I’m wondering if additional tests should be considered. Here’s a snapshot of my liver enzyme levels: - ALKP-Total: Highest recorded was 369 IU/L in December, while my latest measurement on June 4 reads 173 IU/L. - (SGOT) AST: Maximum was 100 IU/L previously, now down to 36 IU/L. - (SGPT) ALT: The peak was 187 IU/L, and my current level has dropped to 70 IU/L.
Answers (1)
7/14/2025, 4:50:43 AM
OpenHealth AI
It's great that you're seeking to understand your liver function tests. Elevated liver enzyme levels can be concerning, but it's encouraging that you've seen recent improvements. Here’s how to understand your situation better and the next steps you might consider.
Main Points
Your elevated liver enzymes may be related to non-alcoholic fatty liver disease (NAFLD) from your pregnancy, which, in many cases, can improve over time. Given your recent decrease in enzyme levels, the situation seems to be improving.
Explanation
Liver enzymes, such as ALKP (alkaline phosphatase), AST (aspartate aminotransferase), and ALT (alanine aminotransferase), are indicators of liver health. An elevation in these enzymes can signal inflammation or damage in the liver. In your case, the recent declines in AST and ALT levels suggest that your liver is recovering, possibly related to lifestyle changes or the body's natural healing process post-pregnancy.
Next Steps
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Monitor Your Progress:
- Continue tracking your liver enzyme levels through regular blood tests as advised by your healthcare provider.
- Keep an eye on any symptoms like fatigue, abdominal pain, or jaundice (yellowing of the skin) and report these to your doctor.
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Focus on Lifestyle Changes:
- Diet: Emphasize a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, and reduce processed foods high in sugars and fats.
- Physical Activity: Incorporate regular exercise into your routine, such as walking, swimming, or yoga, focusing on at least 150 minutes of moderate-intensity exercise each week.
- Weight Management: Since NAFLD is often associated with excess weight, gradual weight loss (if advised) might also help improve liver health.
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Discuss Testing Options:
- If enzyme levels fluctuate again or don’t improve, consider asking your doctor about additional tests, like imaging studies (e.g., an ultrasound) or tests for liver fibrosis, to get a clearer picture of your liver health.
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Medication Review:
- Discuss with your healthcare provider the medications you’re taking, including Diclofenac, as long-term use of certain NSAIDs may impact liver health. Your provider may recommend alternatives if necessary.
Feel free to reach out if you have more questions or need additional clarification. Your proactive approach is essential, and you are taking important steps for your health.
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