Concerns About Possible Serotonin Syndrome: 26F
Hello everyone, I recently consulted with my psychiatrist and we decided to introduce Qelbree, an ADHD treatment, into my existing medication plan. At present, I'm taking Wellbutrin XL, Effexor, Abilify, and Fioricet for migraine relief. After just two days of the new medication, I began experiencing a troubling set of symptoms at work. These included tremors, muscle stiffness, and a resting heart rate that shot up to 134—something I monitored using our office's blood pressure and heart rate equipment. Additionally, I felt flu-like symptoms such as fever and chills, along with intense body and muscle aches that have been quite overwhelming. I opted to stop taking Qelbree today; however, the flu-like feelings persist, even though the tremors and rapid heartbeat have diminished. In an effort to address these symptoms, I contacted poison control, who recommended that I visit the emergency room. I'm unsure whether to wait out the flu-like symptoms, and I'm curious about how they would manage such a situation at the ER. Furthermore, would it be wise for me to go to work tomorrow? Should I halt my regular medications, or would that risk exacerbating my condition if I discontinue them abruptly? Unfortunately, I couldn’t get in touch with my psychiatrist since it’s Sunday. Any advice would be greatly appreciated!
Answers (1)

7/14/2025, 4:20:35 AM
OpenHealth AI
It sounds like you're experiencing some very concerning symptoms after starting Qelbree, which could potentially be related to serotonin syndrome or an adverse reaction. It’s important to take these symptoms seriously. Here’s a breakdown of what you should know and the steps you can take:
Main Points
- Monitor Symptoms: Continue to keep track of your symptoms, especially if they worsen.
- Consider Emergency Care: Given your symptoms and the advice from poison control, it is wise to seek medical attention.
- Medication Management: Do not abruptly stop current medications without guidance, as this can lead to withdrawal symptoms.
Explanation
- Serotonin Syndrome: This condition occurs when there's too much serotonin in the brain, often due to medication interactions, and can present as tremors, muscle stiffness, increased heart rate, and flu-like symptoms. Your rapid heart rate and other symptoms after starting a new medication are significant.
- Flu-like Symptoms: The persistence of flu-like symptoms after stopping Qelbree could indicate that your body is still reacting, and they should be evaluated by a healthcare professional.
Next Steps
-
Seek Emergency Care: Given your symptoms – particularly the tremors, increased heart rate, and flu-like feelings – going to the emergency room is a suitable option. They will conduct a thorough evaluation and likely perform blood tests, vital sign monitoring, and provide supportive care.
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Avoid Work Tomorrow: Given your current symptoms, it’s best to take a day off work to allow your body to rest and recover. Going to work while feeling this way could exacerbate your condition and may not be safe for you or your coworkers.
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Medication Guidance: Do not stop your medications without consulting your psychiatrist or a healthcare professional. Since it’s Sunday, if you are unable to reach your psychiatrist, it's still important to inform emergency department staff of all the medications you are taking. They will best guide whether any adjustments are necessary.
Reminder
Please prioritize getting medical help, as symptoms like you’re experiencing can require immediate attention. Your health and safety are the most important considerations right now. Let me know if you need any more information!
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