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Elevated Hematocrit and Low MCHC: Seeking Answers

7/13/2025, 10:30:27 PMMale25-34

For several months now, I have been experiencing significant fatigue, accompanied by discomfort in my legs and an overall sense of unwellness. As a typically active woman in my sixties, it’s concerning that I find myself needing to sleep for 9 to 10 hours each night and still require additional naps during the day. Recent bloodwork has indicated that my hematocrit levels are unusually high, while my mean corpuscular hemoglobin concentration (MCHC) readings are surprisingly low. Unfortunately, I won’t be able to consult with a specialist for a few weeks. I’m curious if anyone has insights into what might be behind these unusual results?

AgingFamily MedicinePreventive Medicine

Answers (1)

Cony

7/13/2025, 10:30:43 PM

OpenHealth AI

Your symptoms of significant fatigue and unusual blood test results may be interconnected, and it's understandable to feel concerned about these changes in your health.

Elevated hematocrit levels indicate that the proportion of blood volume occupied by red blood cells is higher than normal. This can happen due to dehydration, living at high altitudes, or conditions that increase red blood cell production. Conversely, a low mean corpuscular hemoglobin concentration (MCHC) suggests that the red blood cells may not be well-formed or contain sufficient hemoglobin, potentially due to anemia or other underlying issues.

Explanation:

  1. Hematocrit: High levels can signal various conditions or reactions in the body, often linked with low oxygen levels, dehydration, or blood disorders.
  2. MCHC: Low levels often indicate that red blood cells either lack hemoglobin or are smaller than normal, which is common in types of anemia.

These blood results, combined with your symptoms of fatigue and leg discomfort, suggest that your body may not be effectively oxygenating tissues, which can lead to tiredness. Fatigue levels can also fluctuate with age, physical activity, and overall health.

Next Steps:

  1. Stay Hydrated: Ensure you're drinking enough fluids to avoid dehydration, which can impact hematocrit levels.
  2. Nutrition: Focus on a balanced diet rich in iron (meats, legumes, leafy greens) and vitamin B12 (fish, dairy, fortified cereals) to support blood health and potentially improve hemoglobin levels.
  3. Monitor Symptoms: Keep track of your fatigue levels and any changes in discomfort or general well-being over the next few weeks.
  4. Rest Appropriately: Continue to prioritize sleep and pacing your daily activities, taking breaks as needed.
  5. Await Specialist Consultation: Prepare details of your symptoms and any patterns you notice for when you do meet with the specialist.

If you notice changes in your symptoms, such as increasing fatigue, shortness of breath, or leg swelling, consider seeking care sooner. It's vital to address feelings of chronic fatigue and investigate the causes behind abnormal blood results.

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