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Could My Hepatitis B Test Be a False Positive?

7/13/2025, 5:30:22 PMMale25-34

Greetings, Reddit medical community, I recently underwent a Hepatitis B surface antigen test, and to my dismay, it yielded a positive result. I’m feeling quite devastated by this news. To provide some context, I received a Hepatitis B vaccine just two days before the test. Although I was immunized during my childhood, I decided to get a booster shot. Additionally, my HBsAB levels were reported at approximately 8.9, which is slightly below the required threshold for immunity, set at 10. My main inquiry is: what are the chances that the recent vaccination could have influenced a temporary positive test outcome? It’s worth mentioning that I have engaged in unprotected intercourse since my last negative Hep B test, albeit exclusively with individuals who should have been vaccinated as well. I am planning to conduct further tests later this week, but I'm currently consumed by anxiety and uncertainty. Any guidance or insights you could provide would be immensely appreciated. Thank you for your help!

VaccinationAgingPreventive Medicine

Answers (1)

Cony

7/13/2025, 5:30:41 PM

OpenHealth AI

I'm sorry to hear about your positive Hepatitis B test result; it's completely understandable to feel anxious in this situation. Let's explore your concerns and clarify the possibilities.

Key Points:

  1. Recent vaccination can lead to a transient positive result.
  2. Further testing is crucial to confirm your status.

Explanation: When you receive the Hepatitis B vaccine, it stimulates your immune system to produce antibodies against the virus. Typically, the vaccine is effective in helping your body develop protective immunity. However, shortly after vaccination, especially within a few days, it can sometimes lead to a positive result for Hepatitis B surface antigen (HBsAg) due to the immune response being activated. Since you're above the threshold for HBsAB but below the protective level, it suggests your body is still in the process of responding to the vaccine.

However, it's important to consider other factors that might have contributed to a positive result, such as potential exposure to Hepatitis B, especially given that you've had unprotected intercourse.

Next Steps:

  1. Stay Calm: While it's natural to feel anxious, know that a positive result doesn’t definitively mean you have an active infection until confirmed by additional testing.
  2. Schedule Follow-Up Tests: Ensure you undergo further tests, including HBV DNA testing and possibly other marker tests (like HBeAg), to accurately assess your Hepatitis B status.
  3. Monitor Symptoms: Be aware of any new symptoms, such as fatigue, jaundice (yellowing of the skin or eyes), or abdominal pain, and note them to discuss with your healthcare provider.
  4. Consider Counseling: If anxiety persists, consider speaking with a mental health professional or a support group to help process your feelings.

Your health is paramount, and taking these steps will help provide clarity. If you have more questions or need further assistance, don’t hesitate to reach out.

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