Exploring the Reality of PSSD: Insights Needed
As a 24-year-old female currently prescribed escitalopram for the treatment of panic disorder, I've been using this medication for approximately three months. Fortunately, I've been managing well and have mostly overcome the initial, challenging side effects that came with starting the medication. However, my recent discovery of the PSSD subreddit raised some concerns for me. It appears that much of the discourse around PSSD is rooted in personal experiences and subjective opinions. Consequently, I am eager to understand from a medical perspective: how frequently do you, as a healthcare professional, encounter cases of PSSD? I’m specifically referring to persistent symptoms such as anhedonia, emotional numbness, genital insensitivity, and issues with incontinence that may arise following the cessation of SSRIs, rather than temporary sexual dysfunction during or shortly after treatment.
Answers (1)

7/13/2025, 10:20:32 AM
OpenHealth AI
PSSD, or Post-SSRI Sexual Dysfunction, is a condition where individuals experience persistent sexual dysfunction after stopping selective serotonin reuptake inhibitors (SSRIs) like escitalopram. While your concerns are valid, the prevalence and mechanism of PSSD are still being studied, and it remains a somewhat controversial topic in the medical community.
Key Points:
- PSSD is characterized by symptoms such as anhedonia, emotional numbness, genital insensitivity, and other sexual dysfunctions that persist after stopping SSRIs.
- Research indicates that while some patients report experiencing these symptoms after discontinuation of SSRIs, the overall incidence is relatively low compared to the vast number of people using these medications.
Explanation: While reports from patient communities can be concerning, the scientific understanding of PSSD is still evolving. Most people trialing SSRIs do not experience severe long-term effects after discontinuation. Temporary libido changes or sexual dysfunction during treatment are more commonly discussed in clinical settings than long-lasting symptoms.
Next Steps:
- Monitor Symptoms: Keep a journal of your current experiences and feelings related to any changes in sexuality or emotional responses. This can provide clarity on whether you notice discomfort.
- Educate Yourself: Continue researching through reputable medical sites or literature to distinguish between personal accounts and research findings.
- Communicate With Your Prescriber: If concerns about sexual function or emotional well-being arise, discuss these with your healthcare provider. They can provide tailored advice, assess your risks, and help determine if any adjustments in medication are needed.
Keep in mind that it's important to prioritize your mental health and that open conversations with your healthcare provider can be very beneficial for your ongoing treatment.
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