Worsening Liver Enzyme Levels After Treatment with Transmetil and Inlex
Three weeks ago, I had elevated SGPT and SGOT levels measuring 200 and 80, respectively. Alongside this, I underwent a hepatitis panel, ANA tests, thyroid function assessment, and lipid profile, all of which returned normal results. An ultrasound showed no signs of damage, and a Fibroscan indicated no issues. My doctor attributed these enzyme elevations to transaminitis and recommended a two-week course of Transmetil and Inlex. After the treatment, I was retested, and surprisingly, my SGPT levels have soared to 400 while SGOT is now at 234. I'm puzzled by this increase since I expected the medication to help lower these values. I'm feeling quite uncertain about the situation, and I would greatly appreciate any insights or advice. Thank you!
Answers (1)
7/11/2025, 2:20:42 PM
OpenHealth AI
It's understandable to feel uncertain and concerned about the significant increase in your liver enzyme levels after treatment, especially when you were expecting improvement. Elevated SGPT (ALT) and SGOT (AST) levels can result from various factors, and further evaluation is key to understanding your situation.
Explanation: Your initial tests indicated elevated liver enzymes, potentially due to factors like medication effects or mild liver inflammation (transaminitis). Transmetil (essential phospholipids) and Inlex (a blend of herbal ingredients for liver health) are often used to support liver function, but not every treatment works the same for everyone. The surprising rise in enzyme levels could be due to several reasons, such as:
- An adverse reaction to the treatments you took.
- Underlying conditions that were previously undetected.
- Lifestyle factors like diet or alcohol consumption, which can exacerbate liver enzyme elevations.
- Other medications or supplements that may interact with your liver health.
Next Steps:
-
Track Symptoms: Keep a detailed diary of any symptoms you experience, including fatigue, abdominal pain, or additional changes in your body. This information can be useful for your healthcare provider.
-
Monitor Lifestyle Choices: Evaluate your diet, alcohol intake, and any new medications or supplements you may have started. Aim for a balanced diet rich in fruits, vegetables, and lean proteins, and stay well hydrated.
-
Follow-Up Tests: It's important to communicate with your healthcare provider about these elevated levels. They may recommend further tests, such as additional liver function tests or potentially a referral to a hepatologist (liver specialist) for more thorough investigation.
-
Stay Informed and Supported: Consider seeking patient support groups or forums where individuals with similar health concerns share experiences. This can help you feel less isolated and gain reassurance.
-
Avoid Self-Medication: Until you understand the cause of the rising enzyme levels, avoid taking any new medications or supplements unless advised by your doctor.
If any new symptoms arise or if you continue to feel uncertain, prioritize contacting your healthcare provider for additional guidance. Remember, you are not alone in this process, and seeking clarity will empower you as you navigate your health journey.
Related Questions
Concern Over Swollen Area on the Neck
To provide some background, I am a 35-year-old female in generally good health, aside from a well-managed autoimmune skin condition. I do not partake in smoking or alcohol consumption. Approximately one year ago, I sought medical advice due to difficulties with swallowing, during which I discovered a small lump situated on my neck, just beneath the chin and slightly right of my esophagus. After assessment, it was determined that my swallowing issues stemmed from gastrointestinal complications, which were promptly addressed. I underwent an ultrasound of my neck at that time, and the results were entirely normal. Although I never identified what the lump actually was, the clear ultrasound findings and my ability to swallow comfortably led me to leave it unmonitored. Now, this week, I've observed that the lump has become red, itchy, and noticeably larger. It resembles an insect bite and has an oval shape approximately the size of a quarter. I've scheduled an appointment with my general practitioner; however, the earliest I could get in is late next week. With pre-existing health anxiety, I find myself quite anxious, entertaining fears that this could be cancer, such as lymphoma. Could it be possible that the ultrasound failed to detect something significant? I am unsure about the capabilities of an ultrasound, but I distinctly recall pointing out the lump to the technician a year ago, and she made sure to examine that area thoroughly.
Experiencing Dizziness with Phone Use and Motion Sickness
At 22 years old, I stand at 5'8" and weigh 148 pounds. I’m currently prescribed venlafaxine and Paxil, which I have been taking together for several years to help manage my PTSD symptoms. My nutrition is well-rounded, and I typically engage in about an hour of walking daily. Stress levels are currently low due to a slow work pace, and I maintain a high water intake, seldom consuming alcohol or marijuana. Yesterday, I embarked on a brief car journey and unexpectedly started feeling nauseous, which is quite out of the ordinary for me. I attempted to check my navigation on my phone, and suddenly, my queasiness intensified. Once I returned home, I studied on my laptop without any issues, prepared meals, tidied up, and felt like everything had returned to normal. However, during my commute to work today, I again began to experience motion sickness. Since this morning, whenever I briefly use my phone, I’ve been hit with dizziness and a sensation of disconnection from reality. My phone interactions have been minimal—just opening Spotify to switch playlists and replying to a quick message from my boss. This whole situation has me puzzled, as I've never encountered such symptoms before.
Concerning Fluctuations in Health Measurements
Age: 37, Weight: 45 kg, Height: 171 cm Former smoker; currently uses vaping devices. **Existing health issues:** - Osteoporosis - Hiatus hernia - Chronic neutropenia - Lymphopenia - Peripheral neuropathy **Current medications:** - Concerta 36 mg, taken twice daily - Lorazepam 1 mg, as needed (up to twice daily) Over the last two weeks, I've experienced a decline in my overall well-being, but I’ve been feeling unwell for about two years without any clear diagnosis. I haven't undergone any medical evaluations or routine check-ups in the last year. Recently, my Apple Watch has been recording abnormal data that I find concerning. I believe the condition I may be experiencing is referred to as tachy-brady syndrome, although I am not entirely sure. My respiratory rates have shown unusual fluctuations, something I have not encountered before. Notably, I've recorded three significant spikes in my readings: - June 28th, from 15:00 to 17:00: a shift from 25.5 bpm to 7.5 bpm - July 6th, from 05:00 to 12:00: a drop from 22.5 bpm to 8 bpm - July 9th, from 03:00 to 05:00: a change from 28 bpm to 8.5 bpm Additionally, my heart rate has followed a similar pattern, varying significantly and frequently throughout the day, often fluctuating from 40 or 50 bpm up to 110 or 130 bpm within the same hour. I have also noticed that my heart rate variability (HRV) sometimes dips into single digits, occasionally as low as 5 ms. For the past two years, I have battled with symptoms, including sudden jolts of breath followed by moments of hearing loss accompanied by ringing. There are stabbing pains in my legs, and my body often feels heavy. Fatigue has rendered me nearly bedbound over the past year, making it difficult to stand or move without feeling excessively tired. I also experience sharp, stitch-like chest pains that seem to come and go. In the last week, my appetite has diminished significantly, and I sometimes feel dizzy, whether I'm standing or lying down. I’m questioning the seriousness of these symptoms and whether they warrant concern, as my previous medical exams have not indicated any issues. It’s perplexing to consider whether I might be overreacting, or how reliable the data from my Apple Watch is. However, these readings are new for me, and they correlate with my worsening condition. I understand that anyone online can't provide medical advice and that consulting a healthcare professional is the best course of action. Yet, I’m left wondering just how troubling this situation is. After feeling unwell for such an extended time without a clear diagnosis, I feel lost on how to assess my health status effectively.
Eye Discomfort and Swelling Concerns
Greetings! I’m a 32-year-old male, and I've been experiencing noticeable swelling and discomfort around my eyes for several weeks. Initially, this issue started with pronounced dark circles under my right eye, which later progressed to swelling of the eyelid. Currently, I find myself dealing with painful bags beneath both eyes, which have become red, swollen, and consistently painful - almost like a stinging sensation that doesn’t let up. Interestingly, these episodes typically occur 2 to 3 times a year, but they usually affect just my right eye, presenting mainly as dark circles beneath it. It’s unusual for me to have eyelid swelling like this; normally, it lasts only a few days. For context, I haven’t consumed any alcohol or tobacco since New Year’s Eve, which was seven months ago. I had been a moderate user of both since I was 19. I also used to take allergy medication for many years but stopped that around six months ago, and I've been fine ever since. The same goes for my acid reflux medication; I ceased taking it without any noticeable issues afterward. Currently, I only have a prescription for 20mg Adderall XR, which I take daily. I visited urgent care, where the doctor suspected dermatitis or eczema. I was given hydrocortisone cream to apply cautiously to the affected areas. While it provided temporary relief, the problem persists and remains quite severe. To add to my situation, my sleep is lacking – I typically manage only 4 to 5 hours each night, and I feel overwhelmed with my numerous responsibilities. I would greatly appreciate any advice or insights regarding my condition. Thank you in advance for your assistance! I have shared some images in the comments for reference.
Concerning Symptoms in a 37-Year-Old Male: Potential Health Issues
My partner, a 37-year-old male standing at 5'10" and weighing 185 pounds, identifies as Metis. He leads a lifestyle free from smoking and alcohol, and he isn’t currently prescribed any medications that I am aware of. As a former professional kickboxer, he has sustained numerous head injuries, including a childhood concussion that temporarily erased his memory, leaving him unaware of his own name until he gradually regained it. This background could be pertinent to his current health issues. Over the last couple of months, he has exhibited a range of troubling symptoms. These include episodes of losing his balance, experiencing a persistent metallic taste in his mouth, and displaying cognitive lapses, such as frequently making errors at work and not remembering which street we live on when passing by. He also reports waking up in tears from severe headaches and has resorted to submerging his head in ice water, claiming that it feels like his brain is overheating. Additionally, he has been experiencing sporadic nosebleeds and blurred vision in one eye. His behavior has become increasingly unstable and aggressive. He has developed paranoid thoughts, believing that I am unfaithful to him with his brother. This paranoia escalated to dangerous levels; he discharged a firearm into the air while threatening his brother and even brandished a knife against himself while attempting to compel me to harm him, charging at me but allowing me to evade him in time. Now he plans to travel to Turkey next week for cosmetic surgery, which adds to the odd nature of his actions. Recently, he underwent an MRI of his brain, and only three days ago, a doctor requested that he return for a follow-up MRI. However, he neglected this appointment to once again confront his brother as previously mentioned. He is adamant about avoiding the doctor and the results of his tests. Physically, I feel incapable of persuading him to return to the clinic for further examination. Moreover, he has lost an alarming 40 pounds in just one month due to refusing to eat. I find myself wondering if these symptoms point towards the possibility of a brain tumor or if they suggest chronic traumatic encephalopathy (CTE). My concern for my safety amplifies with his erratic behavior; I genuinely fear for my life due to his condition.