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Strange Blisters After Cellulitis Treatment

7/11/2025, 1:30:27 PMMale25-34

I’m a 22-year-old female, standing at 5'3", and I recently completed a course of antibiotics for cellulitis just yesterday. A couple of days into the treatment, I discovered unusual blisters filled with clear fluid on the leg that was infected. Surprisingly, these blisters have also started to manifest on the opposite leg. They’re not painful, just a bit itchy. Additionally, I experienced a significant sunburn three days before my cellulitis diagnosis. Could this be a lingering effect of the sunburn, or might it indicate a more serious issue? Further details are available in the comments section.

Multiple SclerosisFibromyalgiaInternal Medicine

Answers (1)

Cony

7/11/2025, 1:30:49 PM

OpenHealth AI

It's understandable to be concerned about new symptoms after a recent treatment for cellulitis. The blisters you're experiencing on both legs could be related to a few possible factors, including a reaction to the antibiotics, irritation from the sunburn, or even a dermatological issue that developed during your illness.

Explanation:

  1. Antibiotic Reaction: Sometimes, medications can cause skin reactions. While this happens infrequently, blisters could potentially arise as a response to the antibiotic you've been taking.

  2. Sunburn Effect: If you had a significant sunburn prior to your cellulitis, that skin may have been compromised and could be more prone to developing blisters or irritation.

  3. Infection: Though it is less likely because you’re completing treatment for cellulitis, if the blisters show signs of swelling, increased redness, or warmth, it's important to monitor that closely.

Next Steps:

  1. Monitor Symptoms: Keep an eye on the blisters for changes. Note if they become painful, red, or if you notice any signs of infection like swelling, heat, or fever.

  2. Keep the Skin Clean and Protected: Gently wash the area with mild soap and water, and keep it dry. Applying a gentle, fragrance-free moisturizer might help with the itchiness.

  3. Avoid Irritation: Try to refrain from scratching the blisters, as this can lead to infection. Wear loose, breathable clothing to minimize irritation.

  4. Consider Anti-Itch Solutions: Over-the-counter antihistamines, like diphenhydramine (Benadryl), can help with itchiness. Additionally, topical hydrocortisone cream may reduce inflammation but should be used sparingly.

  5. Seek Further Evaluation: If the blisters persist beyond a few days, worsen, or show signs of infection, it's advisable to seek medical advice. You may need to have them examined to rule out any serious conditions.

Take care of yourself, and remember that many skin reactions can be managed at home, but it’s always best to listen to your body and seek help if needed.

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