Experiencing Shivers from Compazine
Greetings, I'm a 25-year-old male currently hospitalized due to a liver injury. I've been administered Compazine to address my nausea, but I’ve noticed that it triggers uncontrollable shivering and makes me feel extremely cold for about an hour after each dose. Is this a typical reaction? I pieced together this connection last night and have been hesitant to take it since the shivering can be intense. I'm curious if pairing it with Tylenol might help reduce this side effect. Does anyone have insights or recommendations on how to manage this? Previously, I was on Zofran; however, it hasn't been as effective for me compared to Compazine, yet I’m really trying to avoid the shivering episode again.
Answers (1)
7/11/2025, 12:11:25 AM
OpenHealth AI
It sounds like you're experiencing an unusual reaction to Compazine (prochlorperazine), which is generally used to help with nausea and vomiting. Shivering or feeling cold after taking a medication isn't a common side effect, but it can happen in some individuals due to how the medication affects your nervous system.
Understanding Your Symptoms:
Compazine can have several side effects, including sedation, dizziness, and sometimes reactions that cause muscle rigidity or shivering. The intense shivering you experience may be related to how your body is responding to the drug. It's understandable to be hesitant about taking it, especially if it's causing discomfort.
Next Steps:
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Continue Monitoring: Keep track of when the shivering happens — note the time after taking Compazine and the duration. This helps in understanding the pattern of your reaction.
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Hydration and Warmth: Make sure you're adequately hydrated and that you have warm blankets available to help you feel comfortable during these episodes. This can help mitigate the sensation of being cold.
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Avoid Mixing with Tylenol: Pairing Compazine with Tylenol (acetaminophen) isn't recommended solely to manage shivering, as that combination hasn't been proven effective for side effects like shivering. Instead, focus on one medication at a time for nausea — if Zofran worked previously but isn't as effective, discuss this concern with your healthcare team. They might adjust your dosage or suggest different anti-nausea options.
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Communicate with Your Medical Team: Make sure to inform your doctors or nurses about your reaction. They can consider adjusting your medication protocol or exploring alternative medications that may not cause these side effects. Openly expressing your concerns can lead to a better-informed decision about your treatment plan.
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Explore Non-Pharmacological Approaches: In addition to medication, consider non-drug options to manage nausea, like ginger tea or acupressure, although discuss these with your healthcare team first.
Your safety and comfort are the priority. Please remain in communication with your healthcare providers, ensuring they are fully aware of your symptoms and how they affect your wellbeing.
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