Unexplained Blisters on Infant's Back Since Birth
A male newborn, now 3 months old, was born with distinctive blisters located between his shoulder blades. This unusual condition was noted immediately after birth by two pediatricians, who both remarked on the oddity, as such blisters typically occur on the hands or arms from the infant sucking them in the womb—a scenario that isn't applicable here. Initially, the doctors proposed a tentative diagnosis of "erythema toxicum," which was also confirmed by his official pediatrician during a one-month check-up. However, the information I’ve encountered indicates that this condition typically resolves within a week. Now, at three months, although the blisters have diminished, a significant red area persists and occasionally forms a sizeable blister. Remarkably, there has been no spread of the condition, and the infant appears unbothered by it. We refrain from intentionally popping these blisters, though they tend to rupture on their own within one or two days after they appear. Additionally, all maternal labs have returned negative results on two separate occasions. Swabbing was also performed on the affected area (not on the fluid inside the blisters), but those tests yielded negative results as well. We are currently contemplating the nature of this condition and whether to consult a dermatologist. The pediatrician remains optimistic, suggesting that in time, it may heal spontaneously, yet it seems to have reached a stable stage.
Answers (1)

7/10/2025, 3:20:58 AM
OpenHealth AI
It sounds like you're understandably concerned about your newborn's condition involving the blisters on his back. The information you’ve provided indicates that while the blisters have persisted longer than typical for erythema toxicum, the fact that they are not causing discomfort and haven't spread is reassuring.
Overview
The blisters you described are unusual, especially since erythema toxicum is expected to resolve within a week. Given that the condition has stabilized and is not causing distress, it may not be an immediate cause for concern. However, exploring options to understand this condition better is reasonable.
Explanation
Erythema toxicum is a common and usually harmless skin condition in newborns, characterized by small red spots and blisters that can appear in different areas. Though it commonly resolves quickly, some infants experience longer-term variations. It's also worth noting that infant skin can be sensitive and may react in ways that are less common than in older children or adults.
Since your infant is not experiencing additional symptoms such as fever, fussiness, or signs of infection, and the area is stable, this is a positive sign.
Next Steps
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Monitor Symptoms: Keep an eye on the blisters and surrounding skin. Look for any signs of infection (increased redness, warmth, swelling, or discharge). If these develop, it's crucial to seek medical advice.
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Skin Care: Continue to gently cleanse the area with mild soap and water, ensuring not to irritate the skin. Maintain a regular moisturizing routine with a gentle, fragrance-free moisturizer to keep the skin hydrated.
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Consult a Dermatologist: Since the blisters have persisted and remain an area of concern, consulting a dermatologist could provide specialized insight. They may suggest different management strategies or confirm the diagnosis without immediate urgency.
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Documentation: Keep a record of the blisters and any changes that occur. Photograph the area weekly and note any variations in size, color, or texture. This visual documentation can help the dermatologist make a more informed assessment.
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Patience: Given your pediatrician's optimism for possible spontaneous resolution, remain reassured that many infant skin conditions improve with time. However, pursuing a dermatological evaluation can bring peace of mind.
Remember, it’s perfectly normal to have concerns about your child's health, and being proactive about their well-being is a good approach. If more symptoms arise or if you have continuing worries, don’t hesitate to seek help.
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