Could This Be FSGS?
Hello everyone, I'm a 24-year-old male, and three months ago, I experienced a sudden and drastic loss of appetite; I could go several days without eating. Alongside this, I noticed irregular stool and other complications. Initially, I suspected it was a flare-up of my IBS, despite having never lost my appetite due to it before. I consulted my gastroenterologist, who performed an endoscopy, colonoscopy, various blood tests, and everything came back normal. Following this, I underwent an ultrasound. Most organs appeared healthy, including my liver and pancreas, except for my right kidney. It measured 11.6 cm in length and was 0.2 mm taller than normal, presenting a patchy texture and increased echogenicity in the upper region, but no hydronephrosis was detected. My left kidney appeared normal.Beyond that, I've been noticing foam or bubbles in my urine every time I use the restroom, and it can occasionally look cloudy, though that's not consistent. Additionally, I have experienced some headaches, canker sores, occasional mild nausea, and strange sensations on my side or upper right back—though they are not painful, they do come and go. I've had three urine tests (none were 24-hour collections), all of which returned negative results for blood and protein. However, the most recent dipstick test showed trace amounts of protein and a urobilinogen level of 2 mg. I have not had any fever or pain during urination. My glomerular filtration rate (GFR) was recorded at 108, with my red blood cell count exceeding 5, creatinine levels at 1, and a BUN/creatinine ratio of 14. I'm feeling somewhat lost with these findings since, to my knowledge, there's no family history of kidney problems. I maintain a healthy weight, exercise regularly, and follow a balanced diet. I also consulted with a urologist who expressed similar confusion and has requested an MRI for a closer examination of my kidney. Although I understand it's not the most reliable source, my interactions with GPT suggested the possibility of FSGS based on my blood tests and imaging. (My blood work was conducted two months ago.) This situation has made me quite anxious, and I would appreciate any insights from those with similar experiences or symptoms. Thank you!
Answers (1)
7/10/2025, 1:01:32 AM
OpenHealth AI
It's understandable to feel anxious with the symptoms and findings you're experiencing, especially when it comes to something as serious as kidney health. Let’s break down your concerns and next steps clearly.
Main Points: You have experienced a loss of appetite, irregular bowel movements, and changes in your kidney, alongside symptoms like foam in urine and occasional nausea. Your tests so far (including urine tests for protein) have mostly returned normal, but your kidney ultrasound shows some changes.
Explanation: Focal Segmental Glomerulosclerosis (FSGS) is a condition that can lead to kidney damage and may cause symptoms like protein in the urine, fatigue, and increased blood pressure. However, your negative urine tests, good GFR, and normal blood results make it less likely as a cause of your symptoms at this time. The foam in your urine may suggest minor proteinuria, but it’s important to consider other factors or conditions.
The patchy texture in your right kidney and increased echogenicity could indicate various things, ranging from benign conditions like small cysts to more concerning issues. The fact that your left kidney appeared normal is a positive sign.
Next Steps:
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Follow Up with MRI: Continue with the MRI your urologist has requested. This will provide more detailed imaging and help understand the specific changes in your right kidney.
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Monitor Symptoms: Keep a record of your symptoms—especially any changes in your urine (color, foaminess) and appetite—this can be helpful information for your healthcare providers.
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Diet and Hydration: Maintain your healthy habits. Ensure you’re drinking plenty of water, as hydration can help with kidney function. Eating a balanced diet rich in fruits and vegetables can support overall health.
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Stress and Anxiety Management: It's natural to feel anxious in your situation. Consider stress-reduction techniques like mindfulness, deep breathing, or light exercise you enjoy.
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Stay Engaged with Healthcare Team: Keep in close contact with your doctors. If you experience changes, such as new symptoms or worsening current ones, inform them promptly.
Your situation is understandably complex, and it’s reassuring that you are receiving thorough evaluations. Remember, the goal is to understand the underlying cause of your symptoms accurately, and you're taking the right steps by seeking additional imaging and maintaining open communication with your healthcare providers. Please feel free to ask if you have more questions!
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