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Seeking Clarity on a Lymph Node Diagnosis

7/9/2025, 11:10:22 PMMale25-34

Hello, I’m reaching out regarding my twin sister, who has been experiencing swollen lymph nodes along with some minor weight loss for an extended period. Initially, a private ultrasound indicated that the lymph nodes were merely reactive. However, a week later, during an NHS scan conducted for a different issue, she requested a review of her neck. The results revealed that she has a grade 4 lymph node that lacks a hilum. Following this, her GP scheduled an appointment for her, and they were prepared for a biopsy, which is set to take place this Friday. I am seeking guidance on the probability of cancer in this situation. My sister is understandably distressed, and while I’ve tried to remain strong for her, I found myself feeling overwhelmed and anxious tonight. In your professional opinion, what is the likelihood she may have cancer? Thank you for your support.

LupusCOPDInternal Medicine

Answers (1)

Cony

7/9/2025, 11:10:39 PM

OpenHealth AI

It's completely understandable to feel overwhelmed and anxious in this situation, both for your sister and yourself. Swollen lymph nodes and weight loss can certainly be concerning, and awaiting test results can heighten those feelings. While I cannot provide a definitive prognosis or probability of cancer, I can offer information to help you and your sister navigate this difficult time.

Key Points:

  1. Swollen Lymph Nodes: Lymph nodes can swell for various reasons, including infections, inflammation, or malignancies (cancer).
  2. Ultrasound Findings: A grade 4 lymph node with no hilum can be a point of concern, but the context and accompanying symptoms (like weight loss) are vital for a thorough evaluation.
  3. Importance of the Biopsy: The biopsy will provide critical information to determine the nature of the lymph node swelling.

Explanation:

  • Reactive Lymphadenopathy: This is common and can occur due to infections (like a cold) or other benign conditions. Grade 4 lymph nodes might be observed cautiously, especially if they do not have a well-defined structure (the hilum).
  • Symptoms to Consider: Weight loss and persistent swollen nodes could indicate a need for further investigation, hence the biopsy scheduled by her GP.

Next Steps:

  1. Support Her Emotionally: Continue being there for her; your support is invaluable. Encourage open conversations about her feelings and concerns.
  2. Prepare for the Biopsy: Assist her in preparing questions for her healthcare team to clarify what to expect during and after the procedure.
  3. Stay Informed: Once the biopsy results come in, they will guide the next steps. It’s important to wait for the medical evaluation before drawing conclusions.

While waiting for results can feel daunting, reminding yourselves that many conditions are treatable and that her healthcare team is taking proactive steps can provide some reassurance. Make sure to focus on taking care of yourselves during this time. Let me know if you have more questions or need further support.

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