Persistent Knee Swelling: Seeking Guidance
I’m a 25-year-old female dealing with significant discomfort behind my knee, primarily when I try to extend it or twist my knee into certain positions. This started three weeks ago, and initially, I didn't think much of it. About a week later, I consulted an orthopedic specialist, underwent an MRI and X-ray, and the results indicated a bone marrow edema, minor bone contusion, and some swelling within the knee joint. Unfortunately, the swelling has worsened gradually, and I now struggle to bear weight on it. Approximately two weeks ago, I received a cortisone injection, but it hasn't brought any relief. The swelling seems to flare up unpredictably; some days it's manageable, while others—like today—it’s intensely painful. One of my doctors suggested the possibility of rheumatoid arthritis or gout, but I'm feeling lost about the next steps. I’d prefer to avoid visiting the emergency room, yet the relentless pain and uncertainty about the underlying cause are extremely frustrating.
Answers (1)

7/9/2025, 3:50:40 PM
OpenHealth AI
It sounds like you're going through a challenging time with persistent knee swelling and discomfort, and it's completely understandable to feel overwhelmed by this situation. Based on what you've shared, there are several factors to consider and some actionable steps you can take to manage your symptoms and improve your situation.
Key Points:
- Underlying Causes: The worsening swelling and pain following your MRI and X-ray suggest that the issues may not yet be fully addressed. Potential causes include inflammation from conditions like rheumatoid arthritis or irritation related to bone edema or contusions.
- Symptom Management: Since you are experiencing significant discomfort, it is crucial to focus on relieving pain and reducing swelling while you further explore the underlying causes.
Explanation:
Bone marrow edema and contusions indicate that there has been some injury or inflammation to the bone and surrounding tissues. The cortisone injection is intended to reduce inflammation, but it doesn’t always bring immediate relief, especially if there are deeper or more complex underlying issues. If you’re experiencing severe pain and swelling inconsistently, it’s important to find effective ways to manage the symptoms while also considering further evaluation of potential underlying conditions such as arthritis.
Next Steps:
- Activity Modification: Avoid high-impact activities that could worsen your knee's condition. Opt for low-impact exercises (like swimming or cycling) that minimize knee stress.
- Rest and Ice: Make sure to give your knee ample rest. Use ice packs on the swollen area for 15-20 minutes at a time, several times a day, particularly after any activity.
- Compression and Elevation: Consider using a knee brace for support and compression, and elevate your leg when resting to help reduce swelling.
- Pain Management: If not contraindicated, over-the-counter pain relief like ibuprofen can help reduce inflammation and manage pain. Always follow dosage instructions and consult a pharmacist or physician if unsure.
- Tracking Symptoms: Maintain a symptom diary to track your pain levels, swelling, and any triggering activities or foods. This information can be helpful in discussions with your healthcare providers.
- Follow-up: It's essential to revisit your healthcare provider for a thorough assessment of your condition, especially if symptoms persist or worsen. If the possibility of rheumatoid arthritis or gout is raised, further blood tests and evaluations may be necessary to confirm a diagnosis.
If your pain becomes unbearable or if you notice any new symptoms such as severe swelling, discoloration, or a fever, it would be prudent to seek medical attention sooner. Remember, you are not alone in this process, and there are steps you can take to help your knee feel better. Let me know if you have any specific questions or need further assistance!
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