Unequal Pupil Size Concerns
I’m an 18-year-old female and I attempted to overdose on antidepressants yesterday, specifically escitalopram (Lexapro), taking nearly 140 mg, which is not considered a lethal amount. However, I’ve noticed that my pupils are extremely dilated. When I shine a flashlight from my phone on them, my right pupil appears to be larger than the left one. Is this something that will resolve soon?
Answers (1)

7/8/2025, 8:50:38 PM
OpenHealth AI
It’s important to address your concerns about the unequal pupil size and your recent overdose attempt with care and urgency. Unequal pupil size, known as anisocoria, can be a side effect of certain medications, including antidepressants like escitalopram, but it can also indicate other underlying issues, especially in the context of an overdose.
Explanation:
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Dilated Pupils: Antidepressants and other substances can affect the nervous system, leading to changes in pupil size. A single high dose of escitalopram may cause temporary changes like dilated or unequal pupils.
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Anisocoria: This can occur for various reasons, including reactions to medications or potential harm from overdose. It’s essential to monitor this closely as it might signal a need for further medical evaluation.
Next Steps:
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Monitor Symptoms: Keep a close eye on your pupil size and any other symptoms. Make note of any additional changes such as blurred vision, headache, confusion, or unusual physical sensations.
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Stay Hydrated: Ensure you are drinking enough water, as hydration can support your overall well-being, especially after taking high doses of medications.
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Avoid Stimulants: Stay away from caffeine and other stimulants that might affect your nervous system or exacerbate any symptoms.
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Seek Immediate Help: If you notice that your pupil sizes do not return to normal within a few hours or if you experience worsening symptoms like significant dizziness, distressing thoughts, or any change in consciousness, it’s crucial to seek medical help promptly to ensure your safety.
Supportive Measures:
- If you’re struggling, it’s important to talk to someone you trust about your feelings or your situation. Support from friends, family, or mental health professionals can be incredibly beneficial.
Your well-being is essential, and while the physical effects may resolve, getting support for your emotional health after this experience is equally vital. Please take care of yourself and don’t hesitate to reach out for the help you deserve.
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