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Seeking Guidance on Rheumatic Fever Treatment

7/7/2025, 4:50:31 PMMale25-34

Summary: My physician suspects I might have Rheumatic fever and recommends that I receive Penicillin injections every three weeks for the next five years. Is this an appropriate approach for treating Rheumatic fever? Additionally, what potential side effects might arise from consistent Penicillin use over this duration? I am a 28-year-old male who experienced a throat infection accompanied by a fever in May 2025. Initially, I was prescribed antibiotics; however, after completing the treatment, I experienced a recurrence of the sore throat and fever, which occurred three times in total. Following the third episode, I noticed swelling in my knees and experienced migratory joint pain. Consequently, I underwent several blood tests, which revealed elevated levels of CRP and ESR, and an ASO titer of 242. My doctor prescribed a different antibiotic, and after ten days of treatment, my CRP and ESR levels improved. Unfortunately, the joint pain persists. Based on the JONES criteria, my doctor now believes I may have Rheumatic fever. My ECG and 2D Echo results, however, returned normal. As a precaution to prevent future strep infections that could potentially harm my heart valves, the doctor is advising a regimen of Penicillin injections every 21 days for five years. Is this the correct course of action for managing Rheumatic fever? If so, what are the potential implications of receiving Penicillin regularly over the span of five years?

LupusInternal MedicineRheumatology

Answers (1)

Cony

7/7/2025, 4:50:49 PM

OpenHealth AI

It is indeed appropriate to recommend regular Penicillin injections for the prevention of rheumatic fever, especially given your history of multiple throat infections, joint pain, and elevated markers of inflammation. This approach aims to prevent the recurrence of strep throat infections, which can lead to further complications, including damage to heart valves.

Explanation:

Rheumatic fever can develop after an untreated or poorly treated strep throat infection. Penicillin, as a preventive measure, helps to significantly reduce the risk of further episodes of rheumatic fever and its potential long-term effects on the heart. Your doctor is following established guidelines that suggest high-risk patients receive Penicillin injections every three weeks for five years.

Next Steps:

  1. Start the Penicillin Injections: Adhere to the prescribed regimen to effectively prevent future infections. If you experience difficulties or discomfort with receiving the injections, discuss this with your healthcare team.

  2. Monitor Side Effects: Common side effects of Penicillin can include allergic reactions (rash, itching) and gastrointestinal issues (nausea, diarrhea). Rarely, some individuals may experience more severe reactions, so it's essential to report any unusual symptoms to your doctor.

  3. Stay Alert for Symptoms: Keep an eye on any recurrence of throat infections, joint pain, or other new symptoms. Document these in a diary to discuss with your healthcare provider during check-ups.

  4. Regular Follow-Ups: Schedule regular appointments with your doctor to monitor your condition, assess the effectiveness of treatment, and manage any side effects or complications.

  5. Promote Overall Health: Maintain a healthy lifestyle, including a balanced diet, regular exercise, and adequate hydration. Staying healthy can bolster your immune system and potentially reduce the frequency of infections.

It's completely normal to have concerns about ongoing treatment, but this preventive strategy is established based on evidence and aims to protect your long-term health. If you have further questions or concerns, don’t hesitate to reach out for more personalized guidance.

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