OpenHealth Q&A

Get answered by medical professionals

Seeking Guidance on Rheumatic Fever Treatment

7/7/2025, 4:50:31 PMMale25-34

Summary: My physician suspects I might have Rheumatic fever and recommends that I receive Penicillin injections every three weeks for the next five years. Is this an appropriate approach for treating Rheumatic fever? Additionally, what potential side effects might arise from consistent Penicillin use over this duration? I am a 28-year-old male who experienced a throat infection accompanied by a fever in May 2025. Initially, I was prescribed antibiotics; however, after completing the treatment, I experienced a recurrence of the sore throat and fever, which occurred three times in total. Following the third episode, I noticed swelling in my knees and experienced migratory joint pain. Consequently, I underwent several blood tests, which revealed elevated levels of CRP and ESR, and an ASO titer of 242. My doctor prescribed a different antibiotic, and after ten days of treatment, my CRP and ESR levels improved. Unfortunately, the joint pain persists. Based on the JONES criteria, my doctor now believes I may have Rheumatic fever. My ECG and 2D Echo results, however, returned normal. As a precaution to prevent future strep infections that could potentially harm my heart valves, the doctor is advising a regimen of Penicillin injections every 21 days for five years. Is this the correct course of action for managing Rheumatic fever? If so, what are the potential implications of receiving Penicillin regularly over the span of five years?

LupusInternal MedicineRheumatology

Answers (1)

Cony

7/7/2025, 4:50:49 PM

OpenHealth AI

It is indeed appropriate to recommend regular Penicillin injections for the prevention of rheumatic fever, especially given your history of multiple throat infections, joint pain, and elevated markers of inflammation. This approach aims to prevent the recurrence of strep throat infections, which can lead to further complications, including damage to heart valves.

Explanation:

Rheumatic fever can develop after an untreated or poorly treated strep throat infection. Penicillin, as a preventive measure, helps to significantly reduce the risk of further episodes of rheumatic fever and its potential long-term effects on the heart. Your doctor is following established guidelines that suggest high-risk patients receive Penicillin injections every three weeks for five years.

Next Steps:

  1. Start the Penicillin Injections: Adhere to the prescribed regimen to effectively prevent future infections. If you experience difficulties or discomfort with receiving the injections, discuss this with your healthcare team.

  2. Monitor Side Effects: Common side effects of Penicillin can include allergic reactions (rash, itching) and gastrointestinal issues (nausea, diarrhea). Rarely, some individuals may experience more severe reactions, so it's essential to report any unusual symptoms to your doctor.

  3. Stay Alert for Symptoms: Keep an eye on any recurrence of throat infections, joint pain, or other new symptoms. Document these in a diary to discuss with your healthcare provider during check-ups.

  4. Regular Follow-Ups: Schedule regular appointments with your doctor to monitor your condition, assess the effectiveness of treatment, and manage any side effects or complications.

  5. Promote Overall Health: Maintain a healthy lifestyle, including a balanced diet, regular exercise, and adequate hydration. Staying healthy can bolster your immune system and potentially reduce the frequency of infections.

It's completely normal to have concerns about ongoing treatment, but this preventive strategy is established based on evidence and aims to protect your long-term health. If you have further questions or concerns, don’t hesitate to reach out for more personalized guidance.

Related Questions

Seeking Answers for My Brother's Untimely Passing

- A newborn boy was delivered on March 16, 2024, but tragically succumbed to life just 1-2 days later, likely around March 17 or 18. - The pregnancy was categorized as high-risk. The mother received insulin therapy due to a prior pregnancy loss caused by glucose management failures. This history arose from negligent medical care, where she was prescribed glucose without proper monitoring of her blood sugar levels, putting her at risk for diabetes and previously resulting in a pregnancy loss. Over the years, she has given birth to around four children; however, one passed away in utero while the others survived only a brief time post-birth. She currently has one living daughter. - The baby exhibited signs of weakness and had an alarmingly low white blood cell (WBC) count, necessitating his admission to the intensive care unit for approximately one to two days. Despite extensive investigation, the medical team was perplexed by his condition and the reasons for his unfortunate fate. - After his passing, the family noticed numerous bruises and a fractured arm, along with multiple injection sites on his body. - An expensive test was proposed, which would involve extracting blood from his brain, but we were unable to afford this procedure. - I am reaching out for medical expertise: What might correlate low WBC counts, sudden demise, and bruising? Could this be indicative of an immune deficiency, infection, or other health issues? My goals are to: - Identify potential medical conditions related to these symptoms, - Determine whether the observed bruising points to either medical neglect or a health condition, - Understand what preventive measures families can take to avoid experiencing similar heartaches in the future.

DiabetesEndocrinologyRheumatology
Male25-34
2 minutes ago

Seeking Help for a Severe Hair Splinter in My Toe

I am a 27-year-old woman experiencing unbearable pain from a hair splinter lodged in my pinky toe. It became embedded overnight, and upon waking, the agony was intense. Every attempt I made to extract it using tweezers resulted in excruciating discomfort that is difficult to articulate given the size of the splinter. The splinter is so tiny that it doesn’t photograph well, yet the pain it inflicts is anything but minor. I’ve endured various levels of pain throughout my life, but this particular incident ranks among the most severe, especially when I accidentally bump it. My partner is currently picking up Epsom salts so I can soak my foot, but apart from that, I feel lost on how to proceed with removing the splinter. Using tape or a needle seems impractical due to the extreme sensitivity of the area. I would greatly appreciate any suggestions or remedies to help alleviate this situation.

Internal MedicineRheumatology
Male25-34
2 minutes ago

Severe Sprain? A Month of Discomfort

I'm a 26-year-old experiencing persistent pain in my right wrist. There’s a noticeable clicking sound when I move my thumb, and my range of motion is quite restricted. Actions that involve twisting, like opening jars or lids, trigger sharp pain, especially during any abrupt movements. Additionally, I’m dealing with swelling and tightness, particularly when I try to make a fist. This stemmed from a fall where I landed on my outstretched hand about a month ago, after which the discomfort escalated. A CT scan revealed a positive ulnar variance, but my primary care physician downplayed this, claiming it's merely a severe sprain and prescribed steroids. I’m puzzled, particularly because the bone structure seems noticeably misaligned. While ice helps reduce the swelling and pain to an extent, I'm left wondering if seeking a second opinion would be prudent. I appreciate any guidance you can provide on this matter.

ArthritisInternal MedicineRheumatology
Male25-34
2 minutes ago

21-Year-Old Woman with Seronegative RA and Gastroparesis Experiencing Unusual Symptoms

A 21-year-old female has been diagnosed with seronegative rheumatoid arthritis and is undergoing treatment with Humiroz, a biosimilar to Humira, administered bi-weekly. Currently, there is an investigation into possible connective tissue disorders, yet no definitive diagnosis has been established as of now. For pain and fatigue management, she is prescribed Duloxetine at 30 mg, while Prazosin at 3 mg is utilized to address sleep disturbances and nightmares. To manage acid reflux, she has been given Omeprazole at 30 mg. Recently, she underwent a gastric emptying study (GES), which was terminated after four hours due to inadequate stomach movement, leading to a diagnosis of moderate gastroparesis. Despite a slight weight loss of 9 pounds — which is not significant given her already slender frame — she is coping with unexpected health challenges. One peculiar symptom she experiences is a combination of sneezing and vomiting, which she humorously refers to as "snomiting." This troubling occurrence arises approximately twice a week and is often preceded by a mild fever, usually around 100.8°F to 100.9°F, culminating in episodes over the toilet. So far, feedback from healthcare professionals regarding her sneezing and vomiting has been minimal, often reduced to comments noting the oddity of such symptoms. She is eager to understand the underlying cause of this unusual connection between her sneezing fits and vomiting, as it poses a significant inconvenience in her daily life.

ArthritisLupusRheumatology
Male25-34
12 minutes ago

Concerns About Possible Leukemia Symptoms

M31 - Height: 5'10" - Weight: 150 lbs For months, I’ve been grappling with extreme fatigue, which recently escalated into a serious skin infection that arose unexpectedly – specifically, I developed a case of bacterial cellulitis in my armpit. Alongside this, multiple lymph nodes in my arm became noticeably swollen; even after five weeks, they remain enlarged. Additionally, I have been experiencing recurring skin infections. Simple actions like scratching or bumping my skin result in red, inflamed marks that stubbornly refuse to heal. It seems I’m struggling to recover from even minor everyday activities. Moreover, my platelet counts have plummeted by 50% compared to last year. I have also recently been diagnosed with Hypogammaglobulinemia, which adds to my health concerns.

Multiple SclerosisLupusInternal Medicine
Male25-34
12 minutes ago