Could It Be My Liver, Pancreas, IBS, or GERD?
Greetings! I'm a 30-year-old female who has been managing Cushing's disease for the past six years, with successful treatment for the last couple of years. Fortunately, I have experienced minimal disruptions from IBS-M or GERD until recently. Out of the blue, I have gained 22 pounds, despite regularly hitting the gym and adjusting my diet to increase protein intake. A few weeks ago, I noticed my stools became loose, dusty, and bright yellow. Currently, I'm facing challenges with food retention. This isn’t typical for me, as I’ve never encountered such symptoms linked to GERD or IBS before, but given that I'm now 30, perhaps it's a new development? Interestingly, I don’t feel sluggish—on the contrary, I’ve been quite energetic lately, which adds to my confusion. Thank you for taking the time to read my post!
Answers (1)

7/5/2025, 3:30:42 PM
OpenHealth AI
It sounds like you are experiencing several symptoms that are causing concern, including significant weight gain, changes in stool appearance, and difficulties with food retention. Given your history with Cushing's disease, it’s important to monitor these symptoms closely.
Key Points:
- Weight Gain: This can relate to various factors, including hormonal changes or dietary adjustments.
- Stool Changes: Loose, bright yellow stools may suggest malabsorption or gastrointestinal issues.
- Food Retention Challenges: This may indicate underlying digestive problems that need addressing.
Explanation:
Cushing's disease can affect hormone levels that influence metabolism and digestion. The recent weight gain, despite an active lifestyle and dietary modifications, may need further exploration. The bright yellow stools could indicate that your body is not adequately absorbing fats, which can happen for various reasons—including issues with your pancreas or bile production.
Next Steps:
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Monitor Symptoms: Keep a detailed journal of your food intake, stool characteristics, and any additional symptoms (such as abdominal pain or nausea).
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Adjust Diet: Focus on keeping a balanced diet that includes healthy fats, lean proteins, and ample fiber while staying hydrated. This can help with digestion and absorption.
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Consider Stress and Hormonal Changes: Given your history with Cushing's, any stressors or changes in your health could impact your condition. If you notice a correlation with your symptoms and stress levels, consider incorporating stress-reduction techniques like mindfulness or gentle exercise.
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Seek Specialized Support: If your symptoms persist or worsen, especially if you develop new symptoms like abdominal pain or fatigue, it may be prudent to engage with a healthcare professional who specializes in endocrinology or gastroenterology for further evaluation of your digestive health.
These steps aim to help you self-manage your symptoms while ensuring that you capture pertinent information for healthcare providers if you decide to seek further insight. If you have any additional questions or specific area you'd like to delve into, feel free to ask!
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