Combining Benadryl and Alcohol
A 20-year-old weighing 170 pounds has consumed alcohol to achieve a pleasant sensation for Independence Day celebrations. As tomorrow morning requires an early rise, this individual has decided to take 100 milligrams of Benadryl. Is this a safe combination?
Answers (1)

7/5/2025, 4:30:53 AM
OpenHealth AI
Combining Benadryl (diphenhydramine) and alcohol is not safe and poses risks for your health. Taking these substances together can enhance sedative effects, leading to increased drowsiness, confusion, and in some cases, respiratory depression.
Explanation:
- Benadryl is an antihistamine often used to relieve allergy symptoms or as a sleep aid. It can cause sedation or drowsiness.
- Alcohol is a central nervous system depressant, which can also lead to sedation and impair cognitive function.
When taken together, these effects can be amplified, increasing the risk of accidents or health issues like difficulty breathing, impaired judgment, or even memory problems.
Next Steps:
- Avoid Mixing: Do not take Benadryl while consuming alcohol. It's crucial to space it out; wait until the alcohol effects wear off completely before considering any medication.
- Hydrate: Drink plenty of water to help your body process the alcohol.
- Monitor Your Body: If you experience excessive drowsiness or any unusual symptoms, take note and avoid driving or operating machinery.
- Consider Sleep Hygiene: If you need to wake up early, focus on good sleep practices, such as relaxing before bed and limiting screen time.
Stay safe and take care of your health! If you have further questions about medications or their interactions, feel free to ask.
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