Analysis of Synovial Fluid Test Results
I am a 24-year-old female who has been dealing with discomfort in my left hip for the last two years. In November 2023, I visited urgent care due to the persistent pain, underwent an X-ray, and received a diagnosis of osteoarthritis. Approximately six months later, after physical therapy failed to alleviate my symptoms, I consulted a sports medicine specialist. He assessed my limited range of motion in the affected leg, suspected osteonecrosis of the left hip, and referred me for an MRI. The MRI results indicated a significant hip effusion coupled with synovitis. Following this, I have consulted both an orthopedic surgeon and a rheumatologist regarding my hip issue; however, they have yet to determine the cause of my condition. Another MRI was performed to eliminate the possibility of ankylosing spondylitis. Recently, I underwent an aspiration procedure to extract fluid from my hip for analysis. The findings indicated no presence of crystals, and I have included the results of my cellular analysis in this post. If anyone could spare a moment to help interpret these cell count results, it would be incredibly helpful! Unfortunately, I am not scheduled for a follow-up appointment with my physician until September, and I am eager to understand what might be happening based on these findings and whether any further actions are necessary. Thank you so much for your assistance! CELL COUNT RESULTS: Color - Yellow Turbidity - Cloudy Nucleated Cells - 4219/µL Red Cells - 3000/µL MANUAL DIFFERENTIAL RESULTS: % Neutrophils - 1 % Lymphocytes - 72 % Macrophages - 27 % All other cell types - 0 Total Cells Counted - 200
Answers (1)

7/4/2025, 2:31:10 AM
OpenHealth AI
Thank you for sharing your detailed history and test results. It sounds like you've been through quite a journey with your hip discomfort and have taken many steps to find answers. Based on your synovial fluid analysis, I can provide some insights to help you understand the results while waiting for your follow-up.
Summary of Your Test Results:
- Color: Yellow
- Turbidity: Cloudy
- Nucleated Cells: 4219/µL
- Red Cells: 3000/µL
- Manual Differential:
- Neutrophils: 1%
- Lymphocytes: 72%
- Macrophages: 27%
Explanation:
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Color and Turbidity: The yellow and cloudy appearance of your synovial fluid typically suggests inflammation, which aligns with the synovitis noted in your MRI.
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Cell Counts:
- Nucleated Cells: The elevated nucleated cell count (4219/µL) indicates significant inflammation. Normal levels are usually under 200 cells/µL.
- Red Cells: The presence of red blood cells (3000/µL) may indicate bleeding in the joint, which can occur with inflammation or injury.
-
Differential Cell Count:
- The high percentage of lymphocytes (72%) suggests that your body's immune response is involved. Inflammation can signal various issues, including autoimmune conditions or chronic arthritis.
- The low percentage of neutrophils (1%) typically indicates that this is not an acute infection, which would normally present with higher neutrophil counts.
Next Steps:
While you are waiting for your follow-up appointment in September, here are prioritized actions you can consider:
-
Monitor Symptoms: Keep a detailed record of any changes in symptoms. Note if you experience increased pain, swelling, or any new symptoms. This will be valuable for your next appointment.
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Manage Discomfort: Continue with any prescribed physical therapy and pain management strategies. Ice the area as needed and consider non-steroidal anti-inflammatory drugs (NSAIDs) if they're appropriate for you—check with your healthcare provider first.
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Maintain Activity: Gentle range-of-motion exercises and non-impact activities (like swimming or cycling) can help maintain movement and reduce stiffness.
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Seek Clarification: If you have specific concerns or experience new symptoms before your September appointment, consider reaching out to your doctor for an interim discussion.
Support and Reassurance:
Understanding medical conditions can be challenging, especially when outcomes aren't immediately clear. Keep engaging with your healthcare providers, and don’t hesitate to ask questions or express concerns. Each step of this process is important in pinpointing the cause of your hip pain and developing a plan that works for you. Please let me know if you have further questions or need clarification on any point.
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