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Post-Necrotizing Pneumonia Recovery Challenges

7/1/2025, 9:20:34 AMMale25-34

Hello everyone, I wanted to share an update regarding my brother, who is 17 years old and had a significant health crisis. Standing at 6'2" and weighing around 95 kg before his illness, he now weighs approximately 73 to 75 kg after spending 4.5 months in the Intensive Care Unit due to necrotizing pneumonia, which was accompanied by flu, S. aureus PVL+, and pneumococcus, ultimately leading to septic shock. While I am grateful that he survived, he has been left with serious consequences, including the loss of half of his left foot and several toes on his right foot. He recently attended a follow-up appointment in the pulmonology department, and unfortunately, the news was not very promising. I’m seeking insight on the results he received to understand if there’s potential for recovery or whether some conditions might be lasting. Here are the translated findings from his recent tests: 1. **Blood Gas Analysis (with reference ranges)** - pH: 7.47 (Norm: 7.36-7.44) - pCO2: 3.73 KPa (Norm: 5.00-5.60) - PO2: 12.88 KPa (Norm: 11.17-13.83) - Bicarbonate: 20 mmol/L (Norm: 22-24) - Total CO2: 21 mmol/L (Norm: 23-25) - Base Excess: -2.6 mmol/L (Norm: -2.00-2.00) - O2 Saturation: 98% I recognize that the elevated pH is a result of the diminished pCO2. However, is it typical to see such irregular results at this stage? Will these values likely normalize over time? The A-a gradient is measured at 18 mmHg, while the expected maximum is 6 mmHg, indicating that oxygen transfer from the lungs to the bloodstream isn't functioning optimally, despite his excellent O2 saturation. Can we anticipate any improvement through respiratory physiotherapy? 2. **Pulmonary Function Tests** - Total Lung Capacity (TLC): 5.73L (77% of normal) - Forced Vital Capacity: 3.74L (61% of predicted) - FEV1: 2.90L (56% of predicted) - DLCO: 16.32 mL/min*mmHg - KCO: 63% Given that his lungs were severely compromised with 75% infection and could only handle 10-30 mL of air at some points, I’m not too surprised by these results. Is it possible for him to achieve more typical lung function with respiratory therapy? What additional measures could assist in recovering lung capacity? 3. **Imaging Results** His pulmonary artery shows dilation; it was recorded as being 31 mm with PA:A > 1 and this condition has remained stable since his ICU admission. Additionally, he has been diagnosed with varicose bronchiectasis. While it seems the bronchiectasis may be permanent, I am keen to understand its long-term effects. Will this condition significantly hinder his quality of life, or are there effective ways to manage it and maintain control over the symptoms? I apologize for the lengthy message, but since I am overseas and was unable to join my brother at his appointment, I appreciate any insights or advice you can offer. Thank you for your assistance!

AsthmaCrohn's DiseaseCOPD

Answers (1)

Cony

7/1/2025, 9:20:58 AM

OpenHealth AI

Thank you for sharing your brother's situation. It’s clear that he has been through a significant health crisis, and your concern for his recovery is completely understandable. Here’s an overview to help you better understand his recent test results and the potential for recovery.

Key Points:

  1. Blood Gas Analysis: Your brother's results indicate some metabolic imbalances, notably a slightly elevated pH and decreased pCO2.
  2. Pulmonary Function Tests (PFTs): These show reduced lung function, but improvements are possible with appropriate therapy.
  3. Imaging Results: The presence of bronchiectasis and pulmonary artery dilation needs to be monitored, but management options are available.

Explanation of Test Results:

  1. Blood Gas Analysis:

    • The elevated pH and low pCO2 suggest metabolic alkalosis, which can occur due to several factors including hyperventilation or compensation for previous acidosis. It's not uncommon to see irregularities after such a severe illness, especially post-respiratory infections.
    • Next Steps: Regular follow-ups with his healthcare provider will be essential to monitor these results over time and determine if they stabilize.
  2. Pulmonary Function Tests:

    • The tests indicate a significant decrease in lung capacity and function compared to normal values. The results reflect the serious impact of necrotizing pneumonia but improvements may be feasible with targeted intervention.
    • Next Steps: Engaging in respiratory physiotherapy is highly encouraged. Techniques might include breathing exercises, incentive spirometry, and physical rehabilitation to gradually improve lung function. Consistency here is vital.
  3. Imaging Results:

    • Bronchiectasis indicates permanent changes in the airways, which may lead to chronic symptoms like coughing and increased mucus production. However, many individuals with bronchiectasis lead active lives with management strategies in place.
    • Next Steps: A dedicated treatment plan can help manage symptoms. This may include bronchodilator medications, regular chest physiotherapy, and possibly antibiotics during exacerbations. Regular monitoring via imaging can also help assess any progression.

Actionable Recommendations:

  1. Monitor Symptoms: Keep a symptom diary for changes in breathing, fatigue, or any new symptoms. This will be helpful for follow-up appointments.
  2. Engage in Rehabilitation: Start respiratory physiotherapy as soon as feasible. Discuss with his rehabilitation team to tailor a plan to fit his needs.
  3. Action on Bronchiectasis: Consult the medical team about a comprehensive management plan for bronchiectasis, including medication and lifestyle modifications to keep symptoms in check.
  4. Ongoing Support: Regular follow-ups with the pulmonology team are essential to assess his recovery progress and adapt treatment as necessary.

Your brother's recovery journey may take time, but with careful management and support, he can regain functional abilities and improve his quality of life. It's important to stay hopeful and proactive. If you have any further questions or need more specific advice on any point, feel free to ask.

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