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Uneven Swelling in Ankles and Calves

6/30/2025, 6:10:25 PMMale25-34

Female, age 33, standing at 5 feet 4 inches and weighing approximately 390 pounds. Medical history includes ADHD and high triglyceride levels. Currently prescribed medications include Sertraline, Bupropion, Vyvanse, and a cholesterol treatment whose name escapes me—something beginning with F. I started this cholesterol medication roughly three months ago. About a week prior, I noticed that upon waking, my right ankle and foot were noticeably swollen, accompanied by a dull ache in the arch and heel region. I applied ice until my appointment with the chiropractor on Friday. He diagnosed me with plantar fasciitis but indicated that the swelling was unrelated, advising me to inform my primary care physician about it. This morning, I awoke to find the swelling persisted in my ankle, but the pain had subsided. After heading into work, a colleague pointed out that my calf appeared swollen as well. She used my phone to capture images, revealing that both ankles and legs showed signs of swelling, particularly pronounced on the right side. I have no prior incidents of leg or ankle swelling, except during my pregnancy around five and a half years ago.

NutritionAgingFamily Medicine

Answers (1)

Cony

6/30/2025, 6:10:45 PM

OpenHealth AI

It’s understandable to be concerned about uneven swelling in your ankles and calves, especially when combined with pain in your foot. Swelling can stem from various causes, including fluid retention, injury, or underlying health issues. Given your medical history and current medications, let's focus on actionable steps to assess and address this situation.

Main Points:

  1. The swelling could be due to fluid retention or side effects of medications, particularly the cholesterol medication starting with "F," which may be fenofibrate.
  2. Although plantar fasciitis has been diagnosed, the persistent swelling is a separate issue that needs further attention.
  3. Follow specific self-care measures and monitor your symptoms closely.

Explanation:

Swelling in one leg or ankle (edema) can result from multiple factors such as:

  • Venous insufficiency: When veins are unable to pump blood effectively back to the heart.
  • Lymphedema: Accumulation of lymph fluid due to issues with the lymphatic system.
  • Medication side effects: Some drugs contribute to swelling, and fenofibrate is known to affect fluid retention.
  • Injury or inflammation: Previous trauma or conditions like arthritis can also cause localized swelling.

Next Steps:

  1. Track Symptoms:

    • Keep a daily log of your swelling, noting any changes in size, other symptoms like pain, or any activities that may worsen it.
  2. Elevation:

    • Whenever possible, elevate your legs above heart level to help reduce swelling. Use pillows at night to support this.
  3. Reduce Sodium Intake:

    • Decrease your sodium (salt) consumption to minimize fluid retention. Focus on whole foods and avoid processed foods.
  4. Stay Hydrated:

    • Ensure you're drinking enough water to help manage fluid balance.
  5. Gentle Exercises:

    • Engage in low-impact exercises, like walking or swimming, which can promote circulation without excessive strain.
  6. Medication Review:

    • Keep track of all your medications and consider discussing them, especially fenofibrate, with a healthcare professional.
  7. Consult Your Physician:

    • Since the swelling is persistent and has become more pronounced, it is essential to report this to your primary care physician. They may want to perform tests to rule out any serious underlying conditions, such as heart or kidney issues.

Monitoring and addressing the swelling and its causes can lead to better management. If you experience additional concerns, such as shortness of breath, increasing pain, or sudden changes in your symptoms, consider seeking immediate medical attention. Your well-being is important, and these steps can help guide you towards relief.

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