Managing Type 1 Diabetes: Can Metformin and Glipizide Play a Role?
Hello everyone, I’m a 24-year-old female, weighing 110 lbs and standing at 5'5”. I lead a healthy lifestyle, avoiding smoking and alcohol. Recently, I experienced some common symptoms associated with diabetes and had access to a glucose meter. After indulging in a meal of fruit, I decided to check my blood sugar about an hour later and was shocked to see a reading of 260. This was particularly concerning since I’m currently abroad and diligently managing my diet, trying to eliminate carbohydrates until my return. Pursuing a career that requires me to be in good health is crucial, as living with Type 1 or Type 2 Diabetes could potentially limit my options. I share this not to contest standard medical practices, but to recount my father’s experience. He was diagnosed with Type 1 Diabetes at the age of 30 and is now in his sixties. During his diagnosis, his blood sugar was also in the upper 200s. He had numerous disagreements with various doctors due to his aversion to needles. Eventually, he found a doctor open to prescribing an oral treatment plan that included glipizide and metformin, along with an experimental medication that escapes my memory. Remarkably, he has managed his condition successfully for about 30 years. How is this even feasible? Though he still experiences symptoms of Type 1 Diabetes, his latest consultations have once again suggested insulin therapy, which he is reluctant to begin. Instead, he adeptly maintains his health through diet management and an increased dosage of medications. Currently, I haven't received any formal diagnosis, but I’m proactively exploring potential avenues for treatment prior to seeking medical advice.
Answers (1)

6/30/2025, 3:40:41 AM
OpenHealth AI
It’s great that you are being proactive about your health and seeking information regarding diabetes management. Your experience with elevated blood sugar levels and your family history of Type 1 Diabetes raises valid concerns that should be addressed with care.
Key Points:
- Elevated blood sugar readings, especially above 200 mg/dL, can signal diabetes or impaired glucose tolerance.
- Type 1 Diabetes typically requires insulin therapy, while oral medications like metformin and glipizide are primarily used for Type 2 Diabetes.
- Your father’s experience, though unusual, emphasizes the need for a tailored approach to diabetes treatment.
Explanation:
Your blood sugar reading of 260 mg/dL after consuming a meal is concerning, especially if you are managing your diet carefully. It’s important to understand that Type 1 Diabetes usually requires insulin for blood sugar control because the body doesn’t produce insulin at all. Type 2 Diabetes, on the other hand, may initially be managed with medications like metformin and glipizide, which improve insulin sensitivity and stimulate insulin release from the pancreas.
Your father’s management of his Type 1 Diabetes might reflect a unique approach and possibly the use of older treatments that accommodated his lifestyle. However, relying solely on oral medications for Type 1 diabetes is not standard in current medical guidelines.
Next Steps:
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Immediate Monitoring: Keep monitoring your blood sugar closely. Consider logging your readings and any corresponding meals to identify patterns and triggers for high blood sugar levels.
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Diet Review: Since you mentioned trying to limit carbohydrates, focus on a balanced diet consisting of whole foods, emphasizing non-starchy vegetables, lean proteins, and healthy fats. Consulting a dietitian can help you create a plan that balances carbohydrates with your medication or insulin needs.
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Hydration: Drink plenty of water to help your body manage sugar levels and stay hydrated.
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Seek Professional Help: While you are gathering information, it’s crucial to receive a formal diagnosis and appropriate medical advice. Given your symptoms and high glucose levels, consulting an endocrinologist for a thorough evaluation would be beneficial.
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Education on Diabetes Management: Learn about diabetes management from reputable sources. Knowing how to manage blood sugar levels effectively is critical, whether you are diagnosed with Type 1 or Type 2 Diabetes.
Please know you’re not alone in navigating these challenges, and you’re taking important steps toward understanding your health. If you have any further questions or need clarification, feel free to ask!
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