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Concerns Regarding Bupropion and Increased Heart Rate

6/29/2025, 9:00:50 PMMale25-34

A 24-year-old female from New Zealand, currently studying at university and maintaining a sedentary lifestyle, has shared her health concerns following a recent medication adjustment. Standing at 167 cm and weighing 71.2 kg, she has transitioned from sertraline to bupropion over the last month, now taking a dosage of 150 mg daily. Since the change, she has observed a notable rise in her heart rate, estimating an increase from approximately 80 beats per minute to 114 BPM. Additionally, her diastolic blood pressure has escalated from a baseline of 70-80 mmHg to around 90 mmHg. In her current regimen, she also takes 500 mg of valaciclovir once daily to manage cold sores, along with occasional fish oil and vitamin D supplements. For contraception, she receives the depo-provera injection every twelve weeks. She has a long history of SSRI usage, having been on these antidepressants since the age of 14, with sertraline being her primary medication for the last three years. Her concerns regarding the safety of her current dose are valid, especially since her healthcare provider mentioned the option to increase her bupropion dosage after two weeks. She is contemplating whether to maintain her current prescription or double the intake while securing a follow-up appointment with her doctor, potentially one to two weeks into the new dosage. Given these developments, it is important to assess whether this elevated heart rate warrants immediate attention or if adjusting the medication would be advisable. Engaging with a healthcare professional for guidance is strongly recommended in navigating these changes safely.

AgingSupplementsPreventive Medicine

Answers (1)

Cony

6/29/2025, 9:01:18 PM

OpenHealth AI

It's understandable to feel concerned about the changes you're experiencing, particularly with your heart rate and blood pressure after switching medications. Here's a breakdown of what you're experiencing and some actionable steps to take:

Main Points:

  1. Increased Heart Rate: An elevation in heart rate can be associated with bupropion, but it should be monitored, especially with a noticeable change.
  2. Blood Pressure Changes: Slight increases in blood pressure can occur as well, and monitoring these changes is essential.
  3. Medication Adjustments: It’s crucial to make informed decisions about adjusting your medication, and this should be discussed with your healthcare provider.

Explanation:

Bupropion is known to potentially increase heart rate in some individuals, especially at the start of treatment or with dosage adjustments. Your increase from 80 BPM to 114 BPM is notable and deserves attention. Although it's common for some medications to have these side effects, they should not be ignored—especially when they are significant.

The increase in diastolic blood pressure from 70-80 mmHg to around 90 mmHg may also need monitoring, as consistency in these measurements is important for assessing your cardiovascular health.

Next Steps:

  1. Monitor Your Heart Rate and Blood Pressure: Keep a daily log of your heart rate and blood pressure for the next week. This will help track any changes and provide useful information for your healthcare provider.
  2. Assess Your Symptoms: Pay attention to any other symptoms you may experience, such as dizziness, palpitations, or chest discomfort. Note whether these occur during certain activities or at rest.
  3. Engage with Your Healthcare Provider: Plan to contact your healthcare provider soon to discuss your observations. If you feel that your heart rate is exceedingly uncomfortable or if you have any concerning symptoms, don’t hesitate to reach out sooner rather than later.
  4. Consider Lifestyle Adjustments: While you mentioned a sedentary lifestyle, incorporating light physical activity (like walking or stretching) can sometimes help with heart rate and overall well-being. Even small changes can make a difference.

In conclusion, while the medication switch can bring about side effects, careful monitoring and communication with your healthcare provider about these changes are key. You're doing the right thing by being attentive to your body's signals. Let me know if you need further assistance or information!

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