Could This Indicate a Blood Clot?
I’m a 28-year-old female, taking 75mg Synthroid for Hashimoto's hypothyroidism. Recently, about two months ago, I began using a hormonal contraceptive (Lo Loestrin Fe). I’m 5’7” and weigh 180 pounds. As a non-smoker and non-drinker, my health history has been relatively straightforward. Last week on Monday, I began experiencing mild chest discomfort predominantly on my left side and noticed I’ve been short of breath for some time now; I initially attributed this to my inexperience with breathing issues, possible anemia, or an inclination towards POTS. At first, I speculated that the chest pain might be linked to my recent increase in Synthroid dosage from 50 to 75mg, potentially causing my body to approach a hyperthyroid state. Being somewhat anxious about my health, I decided to visit urgent care, where I underwent an EKG and a chest X-ray. Fortunately, both tests showed normal results, which reassured me momentarily. However, last night I experienced a brief episode of coughing that transitioned into hiccups before fading away. This morning, I woke up to a troubling, deep ache in my left leg. I took some aspirin and an Aleve, but I'm still apprehensive about the potential for a blood clot. There’s no noticeable swelling, bruising, or redness, yet I feel generally unwell. The pain does lessen when I lie down with my legs crossed. I would greatly appreciate any insights or advice on this matter. Thank you!
Answers (1)

6/29/2025, 5:50:35 PM
OpenHealth AI
It's understandable to feel concerned given your symptoms and health history. While your EKG and chest X-ray are reassuring, your leg pain combined with shortness of breath does warrant attention. These symptoms can sometimes relate to conditions like blood clots, although they can also stem from less serious issues.
Explanation:
Your symptoms, including:
- Mild chest discomfort
- Shortness of breath
- Deep leg ache
could indeed raise concerns about a blood clot (deep vein thrombosis or pulmonary embolism), especially considering your recent use of hormonal contraceptives, which can increase clotting risk. The absence of noticeable swelling, bruising, or redness in your leg is also a positive sign, although it does not definitively rule out a clot.
Next Steps:
-
Monitor Symptoms:
- Pay close attention to your symptoms. If they worsen or if you develop new symptoms such as severe leg pain, sudden swelling, warmth, or changes in skin color, those could indicate a more urgent situation.
-
Hydrate:
- Ensure you are drinking plenty of water. Dehydration can contribute to clot formation.
-
Gentle Movement:
- Try to avoid staying still for prolonged periods. Gentle movement can improve circulation to help prevent clot risk.
-
Evaluate Pain:
- Since your leg pain lessens when lying down with legs crossed, consider alternating positions to assess if this alleviates discomfort.
-
Schedule Follow-up:
- It would be wise to schedule a follow-up visit with your healthcare provider to discuss your symptoms, particularly the leg ache and how it correlates with your other symptoms. They may consider further evaluation, including ultrasound if a clot is suspected.
-
Continue Monitoring Thyroid Levels:
- Ensure your thyroid levels are monitored regularly, especially after dosage changes, as both hypothyroidism and the medications can impact your overall health.
It’s essential to remain vigilant but also take care of your mental well-being during this time. If you feel your symptoms escalate, don't hesitate to seek additional medical attention. Take care!
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