Concern Over Elevated Platelet Levels at Age 55
At 55 years old, I have a concerning platelet count of 665. Despite this elevated number, I have not experienced any symptoms that could be connected to it. I consulted with a doctor who advised a Complete Blood Count (CBC), but did not consider the high levels to be a significant concern. All my other tests came back normal. I do deal with knee discomfort that sometimes extends throughout my leg, and my doctor has recommended a minor surgical procedure for my knee. However, I'm anxious about the implications of my high platelet count. Even after raising my worries multiple times, my physician has not deemed it serious. Should I seek another opinion? I am particularly apprehensive about the possibility of cancer, even though I have not undergone any biopsies. I would greatly appreciate your guidance!
Answers (1)

6/29/2025, 3:01:42 PM
OpenHealth AI
It's understandable to feel anxious about elevated platelet levels, especially when you're also experiencing discomfort. However, elevated platelet counts, known as thrombocytosis, can occur for various reasons, and many of these are not serious. Let's break this down:
Main Points
- Platelet Count Overview: A count of 665 is considered elevated but may not indicate a serious underlying issue, especially without symptoms.
- Common Causes: Elevated platelets can result from inflammation, stress, infection, or even physical trauma. They can also be reactive rather than indicative of a primary blood disorder.
- Surgical Decision: Your knee discomfort could also tie into inflammation, which could explain both your knee issue and the high platelet count.
Explanation
Platelets are cells that help your blood clot. While a high count can raise concerns about blood clotting issues or other serious conditions, it’s essential to understand that many people with high platelet counts do not have any serious underlying disease, especially if they feel well and have normal results on other tests.
Your doctor did the right thing by suggesting a Complete Blood Count (CBC), as it provides comprehensive insights into your blood health. If all other parameters are normal, this is reassuring. Common causes for elevated counts include:
- Infection or Inflammation: Conditions that induce inflammation (like arthritis or even a recent injury).
- Stress or Exercise: Intensive physical activity can temporarily raise platelet counts.
- Reactivity: Sometimes the body reacts to various stimuli with a temporary increase in platelets.
Next Steps
- Monitor Symptoms: Keep track of any changes in your health, focusing on knee discomfort and any other unusual symptoms.
- Hydrate and Manage Inflammation: Stay well-hydrated and consider using anti-inflammatory measures (like ice therapy to your knee) to help with discomfort.
- Discuss Your Concerns: If anxiety about your platelet count persists or if you develop symptoms (like unusual bleeding, headaches, or vision changes), calmly share these concerns with your doctor at your next appointment.
- Consider a Second Opinion: If you remain worried about your health and potential implications of the platelet count, seeking a second opinion can provide additional reassurance or clarity.
You are not alone in feeling anxious about this; many people have similar concerns regarding blood test results. Address your worries, clarify your treatment options, and take proactive steps toward managing both your knee discomfort and your overall health.
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