OpenHealth Q&A

Get answered by medical professionals

Combining Alcohol with Azithromycin: Is It Safe?

6/28/2025, 10:40:22 PMMale25-34

I’m a 27-year-old male, weighing 380 pounds and standing 5’10” tall. Presently, I’m taking several medications including Omeprazole, Lisinopril/HCTZ, Sertraline, and Loratadine. Today, at 1:00 PM, I completed my treatment with a Z-pack (Azithromycin). I am curious about the potential consequences of consuming alcohol while on this antibiotic. Specifically, I’m contemplating drinking 5 or 6 cans of beer (12 fl oz each) with an alcohol by volume (ABV) of 5.9% while celebrating a fireworks display with my neighbors. Could this combination lead to any adverse effects? Is it advisable to avoid alcohol during my course of treatment? I appreciate any guidance on this matter.

WellnessLifestyle ChangesPreventive Medicine

Answers (1)

Cony

6/28/2025, 10:40:38 PM

OpenHealth AI

Combining alcohol with Azithromycin is generally considered safe for most people, but there are important factors to consider given your overall health and medication regimen.

Overview:

  • Azithromycin does not have a direct interaction with alcohol, meaning it’s not likely to diminish the effectiveness of the antibiotic. However, consuming alcohol, especially in larger amounts, can affect your body’s ability to heal and may amplify side effects from your other medications.

Explanation:

Azithromycin is a commonly prescribed antibiotic and usually does not cause significant interactions with alcohol. However, excessive alcohol consumption can lead to increased side effects like dizziness, drowsiness, or stomach upset, especially with your other medications (e.g., Sertraline, Omeprazole). Given your current medications and your body weight, drinking 5 or 6 cans of beer in one sitting is substantial and could lead to more pronounced effects, including dehydration or potential interactions with Lisinopril and HCTZ, which are blood pressure medications.

Next Steps:

  1. Moderate Alcohol Consumption: If you choose to drink, consider limiting your intake significantly. A small amount may be safer than the 5-6 cans you mentioned.

  2. Hydration: Ensure you are well-hydrated with water before, during, and after consuming alcohol. This can help mitigate some negative effects.

  3. Monitor for Side Effects: Pay attention to how you feel during and after drinking. If you experience increased dizziness, confusion, or any unusual symptoms, stop drinking and rest.

  4. Consult Medication Guidelines: Verify with the guidelines related to your current medications if there are specific recommendations about alcohol use.

  5. Post-Treatment Consideration: Since you completed your Azithromycin treatment today, consider waiting 24-48 hours before drinking significantly. This allows your body to clear the antibiotic effectively.

Enjoy your celebration responsibly; your health is the priority! If you have other concerns or need more specific guidance based on your health status, please reach out.

Related Questions

Interpretation Request for Recent Spinal NM Bone Scan

Hello, doctors. I'm reaching out for your insights regarding a recent NM bone scan of my spine. I've previously undergone a similar scan in 2022, and I'd like to compare the two. To provide context, I am a 29-year-old female weighing 100 kg, and I've been diagnosed with conditions including endplate sclerosis, spinal stenosis, cervical bone spurs, degenerative disc disease (DDD), and mild scoliosis. My medication regimen consists of several prescriptions. Unfortunately, my next appointment with my general practitioner is still a few weeks away, so I would appreciate your assessments on how the latest scan compares to the previous one. Thank you in advance for your help!

AgingWellnessFamily Medicine
Male25-34
1 hour ago

Unexpected Eye Issues: Headache and Double Vision Concerns

A 33-year-old female, measuring 1.67 meters in height and weighing 55 kilograms, residing in the Netherlands, experienced a sudden onset of symptoms. Last evening, shortly after dinner, my partner complained of a slight headache localized at the rear of her head. Along with this discomfort, she encountered double vision and noticed her right eye deviating outward. Interestingly, when she shut either eye, the double vision resolved, enabling her to see without distortion. We rushed her to the emergency room later that night. The medical team conducted a variety of assessments, including physical examinations, neurological evaluations, visual tests, and laboratory analyses. Fortunately, all results were normal. However, the doctors found it peculiar that her right eye exhibited normal movement and accurately tracked a pen in all directions when her left eye was closed. The medical opinion suggested that it may be a migraine-related episode, a condition she has experienced previously. Nonetheless, she insists that this feels unlike any migraine she has had in the past. A teleconsultation with a neurologist is scheduled for Monday to arrange an MRI should the symptoms continue. The doctors advised that if her symptoms worsen, we should return to the hospital immediately. Fortunately, after a night's rest, her vision had returned to normal by morning, the headache had subsided, and her right eye was aligned properly. I am understandably concerned, particularly due to her assertion that this does not resemble a typical migraine. Is it possible that this is indeed a migraine, or could it be indicative of another underlying issue? Thank you for your attention to this matter.

AgingWellnessPreventive Medicine
Male25-34
1 hour ago

Unusual Wave Patterns in ECG: Potential Artifacts in Lead V6

Upon examining the ECG readings, I've noticed peculiar double wave formations appearing between the QRS complex and the T wave in lead V6. This is new to me, as I have never encountered such patterns before. Could these be classified as artifacts?

Family MedicineInternal MedicinePreventive Medicine
Male25-34
2 hours ago

Unexplained Bruises on My Right Hand – Seeking Advice

I've noticed some unusual bruising on my right hand over the past month. Strangely enough, they don't hurt at all. Should I be concerned about this? It's quite puzzling to see these random marks without any apparent cause.

WellnessFamily MedicinePreventive Medicine
Male25-34
3 hours ago

Intense Pain in Left Thumb

Greetings, I’ve been experiencing a piercing pain at the tip of my left thumb intermittently. This discomfort is situated within the thumb rather than on the outer skin. It primarily affects the underside of the thumb and surrounds the base of the nail. The pain seems to extend only to the first skin fold, specifically around the distal phalanx. When applying pressure, I’ve noticed some red streaks appearing beneath the surface, alongside the white area. I trust this explanation is clear. This issue has persisted for over a year, occurring sporadically but intensifying as time has passed. Could this be a cause for concern? A bit about myself: I am a 25-year-old female with no significant medical issues in my background. I previously smoked cigarettes for three years, transitioned to vaping, and have been vaping for six years now. I maintain an active lifestyle, frequently going to the gym and participating in various sports such as indoor football and pickleball. I don’t have any known allergies.

AgingLifestyle ChangesPreventive Medicine
Male25-34
3 hours ago