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Is It Safe to Drink Alcohol After Taking Tylenol?

6/27/2025, 8:10:16 PMMale25-34

I took two 500mg Tylenol tablets around 28 hours ago due to a headache, and now my friends want to go to a new bar. I’m trying to determine if it’s alright for me to have a drink. Given that it’s been over a day since I took the medication, I believe it's probably safe. Just seeking some confirmation on this. Also, I’m a 31-year-old male who is on a daily dose of 50 mg Metoprolol ER for mild high blood pressure, and I don’t have any other health conditions to consider.

Lifestyle ChangesFamily MedicineInternal Medicine

Answers (1)

Cony

6/27/2025, 8:10:34 PM

OpenHealth AI

It's understandable to want clarity regarding alcohol consumption after taking Tylenol (acetaminophen), especially when social plans are on the horizon. Generally, if you've taken a standard dose of Tylenol and it's been more than 24 hours, moderate drinking might be acceptable for many individuals. However, there are some important considerations to keep in mind.

Explanation:

  1. Time Since Last Dose: Since you've taken Tylenol 28 hours ago, it is mostly cleared from your system, as this medication typically metabolizes within a few hours.

  2. Dosage and Frequency: You mention taking two 500mg tablets, which is within the recommended dosage for adults. However, it’s always important to avoid exceeding the maximum dose of 3,000 to 4,000 mg per day to prevent potential liver damage, especially if you plan to drink alcohol.

  3. Metoprolol Interaction: You are also on a daily dose of Metoprolol for high blood pressure. Alcohol can affect blood pressure and may amplify the side effects of this medication, such as dizziness or lightheadedness. It’s wise to be cautious as combining alcohol with blood pressure medications can lead to reduced effectiveness or increased side effects.

Next Steps:

  1. Consider Drinking in Moderation: If you choose to drink, limit it to one standard drink (like a beer, glass of wine, or shot of spirits) to assess how you feel.

  2. Stay Hydrated: Drink plenty of water alongside any alcoholic beverages to stay hydrated and prevent potential adverse effects.

  3. Monitor Your Response: Pay attention to how you feel after drinking. If you experience unusual symptoms or dizziness, it may be best to avoid further drinking and notify a friend to help if needed.

  4. Avoid Heavy Drinking: Try to avoid heavy drinking or binge drinking, as this could increase risks associated with both Tylenol and Metoprolol.

If you have any specific concerns or experience unusual symptoms after drinking, it would be best to consult a healthcare provider directly. Enjoy your time with friends!

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