OpenHealth Q&A

Seeking Answers About My Father's Untimely Passing at 64

To summarize the situation: My father battled ulcerative colitis for over two decades. For much of that time, he was reliant on prednisone, making him dependent on steroids. As the years progressed, his energy levels dwindled significantly, and by October 2023, he had lost interest in activities that once brought him joy. His mental awareness began to diminish, and he appeared unconcerned about his surroundings. Two years prior, he was prescribed Renvoq, which unfortunately led to nighttime episodes of hallucinations—something he kept to himself for a period. Eventually, he shared this experience with his gastrointestinal specialist, who promptly discontinued the medication. Subsequently, he began receiving infusions of Entyvio. Although there was a brief improvement afterward, by October 2023, he became increasingly withdrawn. His blood pressure began to fluctuate, a change we attributed to the process of tapering off prednisone, as he was also on medication for hypertension. Around this time, he complained of his hands being unusually cold and experienced shortness of breath when ascending the stairs. He reported a particular night where he struggled to breathe. Additionally, he noticed slight swelling in one knee, which he dismissed as fluid retention. On January 24, after a small dinner, he stood up to grab a drink from the refrigerator but collapsed back into his chair, drink still in hand, murmuring a distressed “oh god” before losing consciousness. We managed to rouse him briefly; when my mother inquired what had happened, he claimed he had vomited—but that was not the case. He struggled for air, so we immediately dialed 911. In attempts to assist him with his pants, he was unable to lift his body. His hand gestures seemed to indicate pain in his head, and he pleaded for help while we reassured him that the ambulance was on the way. Shortly thereafter, he appeared to have a seizure, and his breathing became increasingly erratic by the time emergency responders arrived. He experienced another seizure-like episode shortly after. Despite the medics' intensive efforts, including administering at least three epinephrine injections to restore a weak heartbeat, he remained extremely pale. The medics advised us not to rush, which led me to believe he was close to succumbing. Once we arrived at the hospital, a family member witnessed them performing chest compressions. Just moments later, we received the heartbreaking news that he had passed. The details on the death certificate listed respiratory failure alongside what appeared to be heart complications, but I am left wondering what could have led to this tragic event. He was only 64 years old. If any medical professionals have insights into possible causes, I would greatly appreciate your feedback.

Answers (1)

6/27/2025, 3:20:56 PM

OpenHealth AI

I'm truly sorry to hear about the loss of your father. This is an incredibly difficult time for you and your family, and it's natural to seek clarity about the events that unfolded.

Main Points

Your father had a complex medical history with ulcerative colitis and treatments that included prednisone and Renvoq, which may have impacted his overall health. His passing appears to be linked to respiratory failure and potential heart complications, likely resulting from a combination of his long-standing health issues, medications, and possibly acute events in his condition.

Explanation

Ulcerative colitis is a chronic inflammatory bowel disease that can lead to various complications, including weakened immunity due to long-term steroid use (like prednisone). This can make the body more susceptible to infections and other serious conditions.

His symptoms of fluctuating blood pressure, cold hands, shortness of breath, and mental changes could indicate several underlying issues, such as reduced oxygenation, heart strain, or even possible side effects from his medications. The hallucinations he experienced with Renvoq and the subsequent changes in his mental status could have indicated neurological effects. The acute respiratory failure leading to his seizure-like episode points to a critical event, possibly related to his heart or lungs.

Next Steps

1. Seek Support: Consider professional grief counseling or support groups for families dealing with loss. It's essential to process your feelings in a safe environment.

2. Medical Records Review: Obtain and review your father's medical records with a healthcare professional who can help interpret the details and provide clarity on the complexities of his medical history.

3. Discuss with Specialists: If you're seeking more insight, consider speaking privately with a gastroenterologist or cardiologist who can help connect the dots among his chronic conditions and the events leading up to his passing.

4. Family Health History: Reflect on your family's health history and discuss with your family any similar conditions, as this may provide context and help address any hereditary concerns for other family members.

5. Self-Care: This moment is heavy. Make sure you're taking care of your own health and well-being during this grieving process.

It’s completely understandable to have questions, and seeking answers is a critical part of healing. Take your time, and don’t hesitate to reach out for further support when you’re ready.