Understanding Slight Elevations in MCV and MPV
Greetings! The title sums it up well. I recently underwent routine blood tests in relation to some persistent but intermittent diarrhea, and I am a 29-year-old male. In reviewing the results, I observed that both my Mean Corpuscular Volume (MCV) and Mean Platelet Volume (MPV) are slightly elevated. While I’m not overly concerned or anxious at this point, I am curious about their significance as I await feedback from my doctor. Notably, besides these two measurements, all other values from my Complete Blood Count (CBC) without differential were reported as normal. Specifically, my MCV is recorded at 99 picograms, while my MPV stands at 11.6 femtoliters. I appreciate any insights on this matter!
Answers (1)

6/27/2025, 12:50:41 AM
OpenHealth AI
Thank you for your question! It’s understandable to want clarity on your blood test results, especially regarding the MCV and MPV values. Here’s a breakdown of what these measures may indicate and what you might consider next.
Main Points:
- Slight Elevations in MCV and MPV: These can be influenced by several factors, often not serious.
- Symptom Context: Given your intermittent diarrhea, the significance of these results may relate to hydration or nutrient status.
- Next Steps: Keep monitoring your symptoms, focus on hydration, and consider dietary impacts.
Explanation:
-
Mean Corpuscular Volume (MCV) measures the average size of your red blood cells. A slightly elevated MCV (like yours at 99 picograms) can be associated with various factors, including:
- Folate or Vitamin B12 Deficiency: These nutrients are crucial for red blood cell production.
- Alcohol Use: Chronic alcohol consumption can affect red blood cell size.
- Liver Disease or Hypothyroidism: These conditions can also influence MCV.
-
Mean Platelet Volume (MPV) measures the average size of your platelets, which are involved in blood clotting. An increased MPV (yours is 11.6 femtoliters) can indicate larger, potentially more active platelets. Slight elevations can occur due to:
- Inflammation or Stress: Conditions affecting the body can lead to changes in platelet size.
- Bone Marrow Production: If your body is producing platelets more actively due to certain conditions.
Practical Next Steps:
- Monitor Symptoms: Keep a diary of your diarrhea—note frequency, duration, and any dietary changes or other symptoms (like fatigue or visual changes).
- Stay Hydrated: Focus on drinking adequate fluids, especially if diarrhea persists. Electrolyte solutions can be beneficial.
- Nutrient Intake: Consider your diet—are you getting enough B vitamins and folate (found in leafy greens, legumes, and fortified grains)?
- Follow-Up: Trust your healthcare provider’s follow-up, but if any new symptoms arise (like weight loss, prolonged fatigue, or severe abdominal pain), be sure to mention them promptly.
Your awareness of these results is important for your health. Once you have feedback from your doctor, it will provide more personalized insights. Please feel free to reach out if you have further questions or need more information!
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