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Exploring Potential Autoimmune Connections in Aging

6/26/2025, 7:50:27 PMMale25-34

I recently underwent some blood tests and a bone density examination in anticipation of my upcoming physical appointment scheduled for late July. At this moment, I am dealing with oral lichen planus and have a mild form of kidney disease. I am a 72-year-old woman, standing at 5'7" and weighing 150 pounds. My current medications address issues related to depression and elevated triglyceride levels. According to the bone density findings, I have osteoporosis, while the blood test indicated the presence of hypothyroidism. Could it be that these conditions are all linked to autoimmune responses? If so, might there be some connections between them? My liver enzyme level was reported at 54 for AST, and alkaline phosphatase was measured at 1.38. That likely pertains to liver function rather than the kidneys, right? I'm feeling quite perplexed about this situation, although not overly anxious. I'm simply seeking insight into these matters before my physical takes place, and I trust your opinions much more than AI-generated responses. Thank you for being here to provide support.

ArthritisLupusThyroid Disorders

Answers (1)

Cony

6/26/2025, 7:50:44 PM

OpenHealth AI

You're experiencing a complex situation with various health concerns, and it's understandable to feel perplexed. Your conditions—oral lichen planus, kidney disease, osteoporosis, and hypothyroidism—can indeed be interconnected, especially in the context of autoimmune responses. Here’s a breakdown of your situation and what you can consider:

Main Points

  1. Autoimmune Connections: Your symptoms may suggest autoimmune activity. Oral lichen planus itself has an autoimmune element.
  2. Bone Health: Osteoporosis and kidney disease can compound health risks, especially as you age.
  3. Liver Enzymes: The levels you mentioned indicate some liver activity, but further evaluation may be needed based on your overall health status.

Explanation:

  • Autoimmunity: Conditions like oral lichen planus can be linked to autoimmune disorders. Hypothyroidism, particularly Hashimoto's thyroiditis, is another autoimmune condition, and the proposed link between autoimmune disorders suggests you might have a predisposition.
  • Bone Health and Kidney Function: Osteoporosis increases fracture risk, which becomes more concerning with kidney issues. Healthy kidneys are necessary to maintain proper mineral balance for bone density.
  • Liver Function: Elevated AST levels can indicate stress on the liver, and while your alkaline phosphatase levels can relate to bone turnover or liver function, the specific context of your overall health is crucial.

Next Steps:

  1. Track Symptoms: Keep a journal of how you're feeling and any changes over time, especially regarding fatigue, pain, or new symptoms.
  2. Hydration and Nutrition: Focus on maintaining hydration and a balanced diet rich in calcium and vitamin D to support your bones and manage your osteoporosis.
  3. Medication Review: Ensure your current medications are well-coordinated for managing depression, triglycerides, hypothyroidism, and any other conditions. If you notice any side effects, note them for discussion with your healthcare provider.
  4. Prepare for Your Appointment: Compile your questions and concerns regarding the autoimmune connections, osteoporosis management, and liver function for your upcoming physical. Bring any results from your tests that might aid the discussion.
  5. Monitor Liver Health: If liver enzyme levels are concerning or rising, your doctor may want to conduct further tests to assess liver health or adjust medications.

It's great that you're seeking to understand your health better. Engage openly with your healthcare provider during your appointment to address these interconnected aspects comprehensively. Let me know if you have any more questions or need further guidance.

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