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Ceasing Cyclizine: A Guide

6/26/2025, 6:30:29 PMMale25-34

29-year-old female here. I struggle with emetophobia and have recently begun therapy to address it. For some time, I've been relying on cyclizine—50mg daily in pill form—as a sort of safety net to manage my anxiety surrounding this phobia. However, I've come to the conclusion that this reliance is a behavior I want to change. The accompanying information for patients doesn’t clarify whether I should taper off the medication gradually or if I can discontinue it abruptly. Understanding that cyclizine is a mildly sedating antihistamine, I hope to gather some guidance on how best to approach this transition. I’m considering the option of splitting the tablet and gradually decreasing my intake, as the thought of stopping suddenly fills me with anxiety. However, I also have concerns about the potential for withdrawal symptoms like nausea if I were to stop taking it outright. If I choose to reduce my dosage slowly, should I expect similar withdrawal effects?

AgingLifestyle ChangesInternal Medicine

Answers (1)

Cony

6/26/2025, 6:30:53 PM

OpenHealth AI

It's great that you’re taking steps to address your emetophobia and questioning the reliance on cyclizine. Stopping any medication, including antihistamines like cyclizine, can be a challenge, especially when anxiety and withdrawal concerns come into play. Here's a breakdown of what you should consider.

Main Points:

  1. Tapering Off Gradually is Recommended: While cyclizine is not known for causing severe withdrawal symptoms like some medications, tapering off slowly can help manage anxiety related to stopping, as well as minimize any potential mild withdrawal effects.
  2. Withdrawal Symptoms Are Possible: Although withdrawal from cyclizine is not common, some people might experience discomfort, such as nausea or increased anxiety, when stopping suddenly or after long-term use.

Explanation:

Cyclizine is primarily used to prevent nausea and is a sedating antihistamine. It acts on your body to reduce feelings of nausea, which might have helped with your phobia. While it doesn’t usually lead to significant withdrawal symptoms, stopping it suddenly can increase anxiety and discomfort, particularly if you have been using it for emotional support. By reducing your dosage gradually, you can give your body time to adjust and mitigate any feelings of anxiety that may arise from discontinuation.

Next Steps:

  1. Tapering Plan: Consider cutting your dosage slowly. You might start by taking a slightly lower dose (for example, 40 mg for a week or two) and monitor how you feel. If you’re comfortable, continue to decrease the dose every week until you can stop entirely.

  2. Document Your Experience: Keep a diary of your symptoms and feelings as you taper off. This will help you track any withdrawal effects and reassure you that you’re progressing well.

  3. Support Alternatives: As you reduce your reliance on cyclizine, ensure you have strategies in place to cope with your anxiety. Continue your therapy and discuss with your therapist any techniques for managing episodes of anxiety that may arise during this transition.

  4. Self-Care Techniques: Employ relaxation techniques, such as deep breathing, mindfulness, or engaging in enjoyable activities, to help manage heightened anxiety during the tapering process.

  5. Monitor Symptoms: Pay attention to how you feel as you reduce your dosage, especially any feelings of nausea or increased anxiety, and adjust your tapering plan if needed.

Always listen to your body during this process, and do what feels right for you. Letting your therapist and support system know about your tapering plan can also provide additional reassurance and support through this transition.

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