Can Methylprednisolone Injections Affect Growth in Adolescents?
An adolescent boy, aged 13.5 years, received a series of Methylprednisolone injections aimed at treating a keloid scar on his knee, measuring 2 inches in length. The treatment consisted of three injections: the initial dose was 40 mg, followed by a second dosage of 12 mg, and a final injection at 8 mg, each spaced two months apart. Is it possible that these doses could lead to systemic effects that might hinder his growth? Thank you for your input.
Answers (1)
6/26/2025, 5:50:34 PM
OpenHealth AI
Methylprednisolone injections, particularly in adolescents, do raise concerns about potential effects on growth due to their steroid nature. In this case, the doses administered to the 13.5-year-old boy for treating a keloid scar were relatively moderate and given over several months, which generally reduces the risk of significant systemic side effects compared to higher doses or prolonged use.
Explanation: Methylprednisolone is a corticosteroid that can potentially influence growth and development in children. Steroids like this can interfere with the hypothalamic-pituitary-adrenal (HPA) axis, leading to reduced natural growth hormone release. However, the degree of impact typically depends on factors such as total duration of use, dosage, frequency, and the individual’s overall health.
For shorter-term treatments or lower doses, like those administered in this case (40 mg followed by 12 mg and 8 mg), the risk of significant growth suppression is usually low, particularly if the injections were intended for localized treatment (in this case, a keloid) rather than widespread systemic treatment.
Next Steps:
- Monitor Growth: Keep an eye on the boy’s growth patterns over the next few months. Regularly measure height and weight, and maintain records to see if there are any significant changes.
- Follow-Up Consultations: Consider discussing growth concerns during future check-ups with a pediatrician, who may recommend monitoring growth hormone levels if necessary.
- Maintain a Healthy Lifestyle: Encourage a balanced diet, regular exercise, and sufficient sleep; all are crucial for healthy growth during adolescence.
- Stay Informed: Be aware of any other symptoms or health changes that may arise after the injections, such as mood changes, weight gain, or heightened susceptibility to infections, and communicate these with a healthcare provider.
By ensuring ongoing monitoring and fostering a supportive health environment, you can help the adolescent boy navigate this treatment safely while addressing any potential growth concerns. Let me know if you need further clarification!
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