Understanding Raised Red and Purple Bumps on the Lower Legs
A 39-year-old female with Ehlers-Danlos syndrome (EDS) and small fiber neuropathy is experiencing the presence of raised red and purple bumps on her legs. Two of these bumps have been noted for a duration of 12 to 18 months, while a smaller bump has emerged in the past 6 to 12 months. What could these bumps signify? Pressing on them causes them to lose color momentarily, which I believe is referred to as blanching. The texture feels rough upon contact. It strikes me as peculiar that these bumps are localized solely on my lower legs. I appreciate any insights or advice regarding this situation!
Answers (1)

6/25/2025, 10:10:36 PM
OpenHealth AI
It sounds like you're experiencing raised red and purple bumps on your lower legs, which can be concerning. Given your background of Ehlers-Danlos syndrome (EDS) and small fiber neuropathy, these symptoms could have several potential explanations. Let's break this down into manageable components.
Main Points:
- Possible Causes: The bumps could be related to vascular issues (due to EDS), inflammatory conditions, or dermatitis.
- Blanching Effect: The fact that the bumps lose color temporarily when pressed (blanching) may indicate they are vascular in nature.
- Location and Duration: The localization and duration of these bumps are important for understanding their significance.
Explanation:
- Ehlers-Danlos Syndrome (EDS) can lead to vascular and skin issues, including bruising and the potential for abnormal blood vessels under the skin, which may appear as red or purple bumps.
- Small Fiber Neuropathy might contribute to unusual skin reactions or sensations in the affected areas.
- The texture and color changes when pressed suggest that these bumps are likely related to blood vessels and may not be fully inflammatory or infectious in nature.
Next Steps:
- Monitor Changes: Keep a close eye on these bumps for any changes in size, color, or new symptoms such as pain or swelling. Note if they change with weather or activity.
- Skin Care: Ensure your skin is well-moisturized and avoid any potential irritants. Gentle skin care can help minimize any further irritation.
- Protect your skin: Given your EDS, be cautious about anything that may lead to injury or further fragility of the skin.
- Document Symptoms: Consider keeping a log of your symptoms, including the appearance, duration, and any associated sensations (like itching or pain) to share with a healthcare provider for better insight.
If you notice any alarming symptoms such as significant swelling, pain, fever, or new widespread rashes, consider seeking medical advice for further evaluation. Let me know if you need any more specific information or tips!
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