Navigating Unexplained Health Concerns: Next Steps to Consider
I am a 33-year-old female with a long-standing history of hypothyroidism, which I've been managing effectively with Armour thyroid for eight years. Recently, I've encountered several troubling symptoms that have left me feeling perplexed. About two months ago, I noticed mild swelling in my right armpit that has remained consistent, neither worsening nor improving. In addition, I am suffering from moderate to severe pain in my right shoulder. A year ago, I also began experiencing intense sensitivity of the skin, making it impossible for me to tolerate lotions, deodorants, perfumes, or any scented washes; exposure to these products results in severe itching and a bright red rash. Throughout this past year, I have dealt with several unexpected episodes of full-body rashes that necessitated treatment with steroids and antihistamines. Furthermore, I have been grappling with intense lower back pain and an unusual degree of fatigue over the last two months. This fatigue has led me to take naps, which is not typical for me. I have struggled with rosacea on my face for several years, but my doctor expressed concern about lupus as a potential underlying issue. Blood tests showed elevated levels of hemoglobin, RBC, hematocrit, and albumin, alongside increased blood pressure; however, retesting four weeks later revealed normal results. Investigations such as an ultrasound of my breasts and armpits, a mammogram, and an MRI of my right shoulder have all been completed, with the only irregularity being mild enlargement of lymph nodes bilaterally. The medical professionals have suggested that this doesn’t clarify the swelling in my right armpit and indicated that I might simply have larger lymph nodes. As a precaution, I've been referred to an oncology specialist, where flow tests were conducted to investigate the possibility of lymphoma or leukemia. Comprehensive autoimmune panels were also run, all of which returned normal results. In terms of my lifestyle, I maintain an active routine consisting of weight lifting and martial arts, adhere to a vegetarian diet, and avoid alcohol, smoking, or drug use. My meals are high in protein yet balanced, and I stay well-hydrated by following a structured meal plan. At this point, I feel uncertain about what additional tests to consider or what other specialists may be helpful. Despite the normal findings, I can't shake the worry that there’s something amiss, and my primary care physician seems unsure of the next steps to take in this ongoing medical mystery.
Answers (1)

6/25/2025, 4:01:43 PM
OpenHealth AI
It sounds like you’re navigating a complex set of health concerns, especially with your ongoing symptoms and the uncertainty surrounding them. Your proactive approach to managing your health is commendable, but I understand how distressing it can be to experience unexplained issues. Here’s a summary of your situation followed by actionable steps.
Summary:
You have a complicated medical history, including hypothyroidism and various troubling symptoms such as swelling in your armpit, shoulder pain, skin sensitivity, fatigue, and skin rashes. While you’ve had numerous tests that came back mostly normal, you’re still experiencing discomfort and uncertainty.
Explanation:
- Swelling and Pain: The mild swelling in your armpit and shoulder pain could be benign, but they deserve careful observation, especially since the lymph nodes are slightly enlarged.
- Skin Sensitivity and Rashes: This might reflect an atypical allergic response or an autoimmune issue, particularly given your doctor's concern about lupus, despite negative autoimmune panels.
- Fatigue and Back Pain: These could be related to various factors, including stress, lifestyle, or underlying conditions.
Actionable Next Steps:
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Symptom Diary: Start a detailed symptom diary. Note the occurrence, duration, and severity of your symptoms, as well as any potential triggers (food, stress, weather changes). This can help identify patterns or correlations.
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Follow-Up on Lymph Nodes: Since the lymph node enlargement was noted, it’s essential to continue monitoring them. Keep records of any changes and discuss them with your oncology specialist.
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Consider Allergy Testing: Given your sensitivity to skin products, it may be beneficial to undergo comprehensive allergy testing (like patch testing) to identify specific allergens contributing to your skin reactions.
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Physical Therapy: For your shoulder and back pain, exploring physical therapy might be useful. A specialist can provide exercises tailored to alleviate pain and improve mobility.
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Consult a Rheumatologist: If not already done, seeing a rheumatologist would be beneficial, especially due to the suspicion of an autoimmune disorder. They may order additional tests or imaging that can provide further insights.
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Lifestyle Factors: Maintain your balanced diet and hydration, and ensure you’re not overexerting yourself in your workouts. Check that you're getting enough rest to combat fatigue.
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Mental Health Support: Consider speaking with a mental health professional. Chronic unexplained health issues can lead to anxiety and stress, and it could be helpful to have support as you navigate this situation.
Final Thoughts:
You are taking a proactive approach in seeking answers, which is crucial. Documenting your experiences will provide valuable insights for you and your healthcare team. If your symptoms worsen or new issues arise, it's crucial to inform your physician immediately. Keep advocating for yourself, and don’t hesitate to ask for referrals to specialists who might offer more tailored insights into your symptoms.
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