Concerns About Worsening Lyme Disease Symptoms After Tick Removal
My mother, aged 54, stands at 5’1” and weighs roughly 170 pounds. She doesn’t smoke and recently discovered a tick lodged in the back of her leg near her knee following a camping trip in Ontario, Canada. After removing the tick, she noticed that its head was still intact and alive. Initially, there was no noticeable redness for about a week, but soon after, the area began to turn significantly red. Concerned about this development, she consulted with a physician who prescribed a 10-day regimen of Doxycycline at 100mg twice daily. However, several days into the treatment, the rash appears to be worsening, becoming even redder. Additionally, she is experiencing severe flu-like symptoms along with persistent dizziness. It is particularly alarming as she has a history of epilepsy, though she has been seizure-free for approximately four months. Illness often triggers her seizures, which raises concerns about the fever and dizziness she’s now contending with. Is this worsening condition typical following the initiation of treatment? In the past, I’ve known family members who dealt with tick bites and received longer courses of antibiotics, up to 18 days. It's also worth noting that at this time, she is not taking any other medications, including those for her epilepsy. To summarize, I’m seeking insight into whether it’s common for her symptoms to escalate after starting Doxycycline and whether the prescribed duration of the antibiotic is standard in such cases. Thank you for any assistance you can provide!
Answers (1)

6/24/2025, 11:10:47 PM
OpenHealth AI
It’s understandable to be worried about your mother’s worsening symptoms following her recent tick bite and subsequent antibiotic treatment. Here’s a structured response addressing your concerns:
Main Points
- Worsening symptoms post-Doxycycline initiation can occur but need close monitoring.
- The typical duration for Lyme disease treatment varies; if symptoms worsen, further evaluation is essential.
Explanation
Doxycycline is commonly prescribed for Lyme disease after a tick bite, especially if the tick is identified as potentially carrying the bacteria (like the black-legged tick in Ontario). Initial symptoms can sometimes become more pronounced as the body reacts to the antibiotic and the underlying infection is addressed.
However, worsening symptoms, particularly severe flu-like symptoms, increased redness at the bite site, and persistent dizziness, may indicate that her condition is not improving. These could be signs of complications or a more severe reaction to the Lyme disease itself.
Given your mother’s history of epilepsy, the added symptoms of fever and dizziness could indeed heighten her risk for a seizure, which makes evaluating her situation more urgent.
Next Steps
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Monitor Symptoms: Keep a close eye on the new or worsening symptoms. If she develops a high fever, increasing redness at the site, or if dizziness becomes severe, act quickly.
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Hydration & Rest: Ensure she stays well-hydrated and gets plenty of rest to support her recovery.
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Consult a Healthcare Professional: Given the escalation of her symptoms, it would be prudent to follow up with her physician or an infectious disease specialist. They might consider extending her antibiotic therapy beyond the initial 10 days or running additional tests to evaluate her condition.
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Document Changes: Keep a record of her symptoms, including dates, temperature, and any other notable changes, as this information can help the healthcare provider assess her situation more effectively.
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Emergency Plan: Have a plan in place to seek immediate medical attention if her condition worsens, especially with her epilepsy history.
It’s crucial to address these concerns promptly to ensure she receives the best care possible. Please stay vigilant and support her through this time. Let me know if you need further assistance or clarification!
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