Concerns About Lack of Sweating on Talvey Treatment
I’m seeking some advice regarding a health issue I’m facing. I’ve been receiving treatment for multiple myeloma with Talvey for seven weeks now, and I’m experiencing a complete absence of sweating, which has persisted for several weeks. In the past, I would sweat easily, often changing shirts multiple times during my workday just from the heat. When I mentioned this lack of perspiration to my nurse practitioner, she suggested it might be a positive sign, but I find that hard to accept. Additionally, I’ve been noticing irregular heart rhythms accompanied by spikes, which were also present before initiating treatment. My cardiologist had previously assured me that my heart conditions were stable enough for treatment. However, I’ve been struggling with increased shortness of breath as well, which I realize is a documented side effect of this medication. Despite my engagement with my healthcare team, I feel unsettled about my symptoms. My appetite has significantly declined; I hardly eat anything anymore, yet paradoxically, I’ve gained three pounds in the past week. My wife and I suspect that my inability to sweat might be influencing this weight change. On the positive side, my blood work shows improvement—my M-Spike has dropped from 2.5 to 0.24, indicating that the Talvey treatment is effective. Still, the transition from feeling unwell due to high numbers to experiencing some relief with treatment, only to feel worse from the side effects, is quite challenging. I appreciate any insights or experiences that anyone might share. Thank you!
Answers (1)
6/24/2025, 8:40:46 AM
OpenHealth AI
It sounds like you’re facing some significant challenges with your Talvey treatment for multiple myeloma. While it’s encouraging to hear that your blood work shows improvement, the side effects you’re experiencing, like the absence of sweating, irregular heart rhythms, shortness of breath, and appetite changes, can understandably be concerning.
Explanation
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Lack of Sweating: The absence of sweating (anhidrosis) can occur due to various factors, including medications or even underlying conditions. While your nurse practitioner suggested this might be a positive sign, you understandably fear it could indicate something else. It's essential to track how you feel with this change, especially considering your body’s prior tendency to sweat easily.
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Heart Arrhythmias and Shortness of Breath: Irregular heart rhythms and shortness of breath are important symptoms to monitor, especially if they worsen. While your cardiologist stated that your heart conditions are stable, any increase in these symptoms should be taken seriously.
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Appetite Changes and Weight Gain: A decline in appetite with weight gain can be linked to changes in metabolism, fluid retention (especially if you're not sweating), or possibly other factors related to your condition or treatments.
Actionable Next Steps
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Monitor Symptoms Closely: Keep a daily log of your symptoms, focusing on the absence of sweating, heart rhythm changes, shortness of breath, and any fluctuations in weight or appetite. Detail when these symptoms occur and their intensity.
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Hydrate: Since you're experiencing a lack of sweating, make sure to stay well-hydrated. Drinking sufficient fluids can help your body manage temperature and support overall health, particularly while undergoing cancer treatment.
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Nutritional Support: Aim to eat small, nutritious meals even if your appetite is low. Consider consulting a nutritionist or dietitian who can provide strategies tailored to your current condition and needs.
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Address Heart and Breath Concerns: If you notice worsening symptoms (increased shortness of breath or heart rhythm irregularities), promptly reach out to either your cardiologist or your oncologist. They might need to reassess your treatment plan or investigate the symptoms further.
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Seek Support: Discuss these ongoing concerns with your healthcare team during your next appointment. Express your feelings about how these side effects are impacting you. They may have additional insights or adjustments to treatment that could help.
If you discover these symptoms are causing significant distress, don’t hesitate to reach out for immediate support from your healthcare team. Your health and comfort should always be the priority.
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