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Discovering the Transformative Power of Glycine for My Health Challenges

6/21/2025, 5:50:20 PMMale25-34

After years of struggling with various health problems, I have recently come across glycine, which has significantly improved my well-being. Now, I am eager to learn more about how it works. My battle with issues like anxiety, depression, IBS, fatigue, mental fog, unexpected weight loss, skin irritations, inflammation, and body aches has spanned over a decade. I've experimented with numerous dietary approaches, including the Paleo diet I currently follow, as well as keto, low FODMAP, antihistamine, gluten-free, dairy-free, and vegan diets. I undergo quarterly blood tests, and my thyroid levels are normal. I've adhered to doctor-guided gut health treatments, which included courses on antibacterial and antiparasitic medications. Although I have been diagnosed with estrogen dominance due to more than ten years on a progesterone-only contraceptive, I am treating this concern with an endocrinologist through hormone replacement therapy. In the past, I tried various SSRI medications, but the side effects were incredibly harsh, and I didn't experience a reliable improvement, prompting me to discontinue them around a year ago. Despite my extensive efforts to improve my health, I was in a constant struggle until just a week ago when I began incorporating glycine powder into my routine after meals. Remarkably, within approximately 15 minutes of taking glycine, the debilitating headache I usually get after eating—a sensation reminiscent of my brain swelling—along with my anxiety, vanished. I've noticed that taking a large dose in the morning does not seem to provide relief during lunch; rather, it appears that consuming it immediately after meals is crucial for optimal results. As a result, I no longer wake up with headaches, my anxiety is the most manageable it has ever been, and I'm reconnecting with feelings of energy and concentration. I would love to delve deeper into the underlying mechanisms that glycine might be influencing, as it seems to counteract symptoms rather than addressing whatever root causes may exist. If anyone has suggestions or insights into this, I'd greatly appreciate your input! Just a bit of context: I'm a health-conscious woman in my mid-thirties and lead an active, fit lifestyle.

NutritionAgingSupplements

Answers (1)

Cony

6/21/2025, 5:50:38 PM

OpenHealth AI

It's great to hear that you’re experiencing positive changes with glycine! Here's a structured overview to help you understand how glycine may be beneficial for your health challenges and some actionable steps you can take.

Main Points:

  1. Glycine's Role: Glycine is an amino acid that plays several important roles in the body, including supporting neurotransmitter function, reducing inflammation, and promoting gut health.
  2. Symptoms and Glycine: Your observed improvements—reduced headaches, lower anxiety, and increased energy—could be linked to glycine's calming effects on the nervous system and its potential role in gut health.

Explanation:

Glycine is not only a building block for proteins but also serves as a neurotransmitter in the brain. It helps with:

  • Calming the Nervous System: Glycine has been shown to enhance sleep quality and may improve overall mood by supporting the brain's inhibitory neurotransmitters.
  • Gut Health: It aids in producing gastric acid and maintaining the integrity of the gut lining, which could benefit your IBS symptoms and improve overall digestion.
  • Reducing Inflammation: Glycine has anti-inflammatory properties that may help alleviate some of your body aches and skin irritations.

The timing of your glycine intake seems effective, as taking it after meals may help regulate postprandial discomfort and headaches, potentially related to gut motility and absorption.

Next Steps:

  1. Continue Monitoring: Keep track of your symptoms and any changes with glycine usage over the next few weeks. Note the specific times you take the supplement and how you feel afterward.

  2. Evaluate Dosage: Ensure you're using a safe dosage of glycine (typically, 3-5 grams per day is a common range), but adjust based on your personal experience and any guidance from your healthcare provider.

  3. Nutritional Synergy: Consider complementing glycine with other supportive nutrients, like magnesium or omega-3 fatty acids, which may also benefit your mood and inflammation.

  4. Hydration and Diet: Continue maintaining a balanced diet while ensuring proper hydration. This is crucial for gut health and overall well-being. The Paleo diet can be inflammatory for some, so listen to your body and adjust as needed.

  5. Stay Educated: Research more on glycine's effects; several studies suggest its benefits for conditions like anxiety and inflammation. This could empower you with more information for discussions with health professionals.

  6. Consult Professionals: Given your complex history and hormonal treatments, it’s wise to periodically review your supplement regimen, including glycine, with your endocrinologist or a nutritionist specializing in gut health.

Your positive strides with glycine are encouraging, and by continuing to prioritize self-care and informed choices, you can further enhance your well-being. If you have further questions about glycine or other health strategies, feel free to ask!

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