OpenHealth Q&A

Get answered by medical professionals

Seeking Answers for Unexplained Foot Discoloration and Pain

6/21/2025, 4:01:06 AMMale25-34

Greetings, I’m a 25-year-old male, measuring 5 feet 8 inches tall and weighing 95 kilograms. I recognize that my weight is above the recommended range, but managing exercise has been challenging due to my symptoms. These issues began in early 2020 and have progressively worsened since. **Medical Background and Treatment**: - I have been prescribed sertraline at a dosage of 150mg for depression, starting in April 2020. - I take pregabalin daily, at 75mg. - I receive Reandron injections every three months for gender transition, beginning in October 2020. - Historically, I experienced insulin resistance between 2013 and 2016, but my blood sugar levels have remained normal since then. After merely a few minutes of standing, my feet develop a purple hue, accompanied by significant pain when I attempt to stand or walk for any length of time. This situation has left me feeling quite desperate, as I struggle to both work and venture outside my home; after just a few hours, I am overwhelmed with pain throughout my body, particularly in my feet and legs, and I experience profound fatigue. The only relief I find is through rest. I have consulted a variety of healthcare professionals, including general practitioners, a vascular expert, a cardiologist, and a neurologist. Their consensus seems to indicate a mix of vascular pooling and a potential case of small fiber neuropathy (SFN), possibly due to a lack of abnormalities in the large fibers. Despite extensive testing, the results have mainly been unremarkable. **Tests Conducted**: - Comprehensive blood tests - Tilt table test for POTS - Sweat test - MRI of the thyroid - Blood pressure assessments - 24-hour urine collection - 24-hour electrocardiogram (EKG) - Blood testing for Fabry’s disease - Large fiber nerve conduction studies I do not have postural orthostatic tachycardia syndrome (POTS), as my heart rate remains stable. The only anomaly noted was during a blood pressure examination involving my arms and legs, where the findings were deemed unusual. Beyond that, there haven’t been any significant discoveries. Although I’m aware of my youth, my pain hinders my ability to engage in many activities, and the lack of a firm diagnosis complicates my path to recovery. **What I’m Seeking**: While I am not anticipating any miraculous solutions, I find myself at an impasse. Medical professionals have not provided substantial insights beyond identifying my symptoms. I am reaching out for guidance—have I overlooked any avenues? Are there additional specialists I should consider consulting, or should I continue seeking opinions from different physicians? I truly appreciate any help or recommendations you might have, and I am willing to provide further details if required. Thank you for your time and consideration!

ArthritisLupusCrohn's Disease

Answers (1)

Cony

6/21/2025, 4:01:38 AM

OpenHealth AI

It sounds like you're dealing with a complex set of symptoms that is understandably frustrating and limiting your daily activities. Your experiences with unexplained foot discoloration, pain, and fatigue, combined with the extensive evaluations you've undergone, indeed point towards a diagnostic challenge. Let's discuss your situation, how to approach this moving forward, and supportive measures you can take.

Summary of Key Points:

  1. Symptoms: You experience foot discoloration, pain, and fatigue, exacerbated by standing, which correlates with potential vascular pooling and small fiber neuropathy.
  2. Medical Evaluations: Extensive tests have returned mostly normal results, with mention of unusual blood pressure responses.
  3. Your Goal: Finding clarity on next steps, potential specialists to consult, and ways to alleviate symptoms.

Explanation:

Foot discoloration and pain, especially during standing, can be related to issues such as poor circulation or nerve function, and the combination of small fiber neuropathy and vascular pooling could explain some of your symptoms. These conditions can lead to discomfort and fatigue when standing or exerting yourself. The lack of a clear diagnosis can be extremely frustrating, particularly when you feel your quality of life is impacted.

Next Steps:

While you continue to seek further assistance, here are some actionable steps you can take:

  1. Symptom Management Strategies:

    • Elevate Your Feet: When resting, elevating your feet on a flat surface can help reduce swelling and improve circulation.
    • Compression Socks: Consider wearing compression stockings to improve blood flow in your legs and potentially alleviate some symptoms of vascular pooling.
    • Gradual Standing: Build tolerance by gradually increasing the time you spend standing. Start with short intervals, and rest frequently to minimize discomfort.
  2. Continued Medical Exploration:

    • Rheumatological Evaluation: Given your symptoms’ complexity and potential overlap with autoimmune disorders, seeing a rheumatologist might help rule out conditions like lupus or other connective tissue diseases that can lead to similar symptoms.
    • Pain Management Specialist: Engaging with a pain management doctor could provide access to therapies specifically tailored to chronic pain, which may include medications, physical therapy, or alternative treatments.
    • Nutritional and Functional Medicine: A consultation with a functional medicine practitioner or a dietitian can explore dietary influences on inflammation and neuropathy, potentially uncovering triggers or supportive approaches regarding your overall health.
  3. Mental Health Support:

    • Continue to prioritize mental well-being during this challenging time. Oftentimes, the impact of chronic symptoms stretches beyond the physical. Engaging with a therapist or support group can be beneficial.
  4. Networking with Support Groups:

    • Consider joining online communities or local support groups for individuals with similar symptoms. Sharing experiences with others can lead to new insights and coping strategies.

Final Consideration:

Be patient with yourself as you explore these avenues. It’s essential to seek expert opinions while also focusing on your immediate comfort and well-being. Keep a detailed symptom diary to track any changes or patterns in your symptoms, which can provide helpful information to any specialists you may consult in the future.

Whenever you need support or have more questions, feel free to reach out. You are not alone, and each step you take brings you closer to finding solutions that work for you.

Related Questions

Jaw Pain on One Side: What Could It Be?

Subject: F23. I recently woke up to an unbearable pain localized on one side of my jaw. The muscles appear to be tense, making it quite difficult to fully open my mouth. That’s the extent of my symptoms for now. This is an entirely new sensation for me. After researching, I encountered suggestions pointing towards TMJ, though I've never experienced any issues like that before, nor can I pinpoint a possible cause. About a week ago, I stepped on a thumbtack, and I do have a tendency to walk around without shoes. However, I don’t have any fever at this moment. Should I seek immediate medical attention, or is it probably just TMJ and I’m overreacting? I can’t recall when I last received a tetanus booster. I’m 4'10'' and typically maintain a good level of fitness. If by chance this develops into tetanus, what are my chances of recovery?

ArthritisInternal MedicineRheumatology
Male25-34
7 minutes ago

Indicators of Cocaine Dependency

I've been on Lexapro and Abilify for my depression for 18 months now. Just to clarify, I’m not looking for the classic "drugs are bad" lecture—I completed D.A.R.E. like everyone else and I know the risks involved. I have a history of addiction related to painkillers. This stemmed from a couple of weeks on fentanyl while in the ICU, but I've managed to stay clean from pain medications for about a year now. Addiction has a strong presence in my family, particularly with alcohol issues. Personally, I have shown addictive tendencies in areas like gambling and shopping, having spent around $4,000 in a month on those activities before I sought help from a counselor. Additionally, I've displayed risky sexual behaviors and have been informally labeled as hypersexual by my counselor, which has contributed to my anxiety. About two weeks ago, I began using cocaine. Initially, it was just a small amount shared with friends, before it escalated to doing lines in social settings, then to using it alone. Now I find myself purchasing full grams to consume by myself. Once I start, it’s difficult for me to stop, and I’ve experienced several nosebleeds as a consequence. Just tonight, I ended up snorting an entire gram within a few hours, despite promising myself it would last a week. My self-restraint has pretty much vanished. When I’m under the influence, I feel more confident socially and much more capable. Cocaine makes me feel alive. It's nearly 5 a.m., and I've been using all night. I worry that this could escalate and ultimately destroy my life. My goal was to enjoy it casually within social settings, but it feels like it's consuming me. Am I on the path to addiction? How can I manage my consumption more effectively?

ArthritisInternal MedicineEndocrinology
Male25-34
7 minutes ago

Concerns About My Lip Condition

I’m a 15-year-old girl, and at the beginning of this week, I noticed that my lips began to swell unexpectedly. They also felt tingly and were painful when touched. After four days of persistent swelling and tingling, blisters developed, along with increased discomfort. The only over-the-counter medication I've occasionally taken is Benadryl, both in pill and liquid form, but I'm not sure that it could be the source of the issue. After researching online, I found information suggesting it could be herpes, which has left me quite puzzled about how that could apply to my situation. My mom doesn’t seem to be taking this seriously and hasn't taken me to see a doctor. I'm really unsure about what steps to take next. 😭

LupusFibromyalgiaThyroid Disorders
Male25-34
17 minutes ago

Seeking Medical Insights on Hemorrhoids

Hello everyone, I hope this message finds you well. I am reaching out to seek your expert opinions regarding my ongoing issues with hemorrhoids. Here are the details of my situation: - There is a noticeable external swelling around the anal area that is hard to reposition after a bowel movement. - While I do not experience pain or bleeding, I do feel discomfort due to the prolapsed condition. - I believe the severity is between **Stage 3 and Stage 4** for internal hemorrhoids. - I have not undergone any surgical procedures in the past. Your advice would be greatly appreciated on the following: 1. What type of surgery might be appropriate for my case (options like HALO, PPH, or more traditional excision methods)? 2. What can I expect in terms of recovery time and potential risks associated with these surgeries? 3. Is the surgical procedure something that should be addressed promptly, or can it wait? Thank you in advance for your assistance. Sincerely, Hasan Emad, 71 years old

ArthritisMultiple SclerosisInternal Medicine
Male25-34
47 minutes ago

Request for Expert Evaluation: Possible K-Wire Migration in Fifth Metacarpal?

Hello everyone, I am a 34-year-old male standing 6 feet 1 inch tall and weighing 75 kilograms. I am reaching out to seek additional opinions from any healthcare professionals, radiologists, or individuals with orthopedic insights. Recently, I suffered a fracture in my fifth metacarpal, commonly referred to as a boxer’s fracture, and underwent surgical intervention that involved the placement of a single K-wire. I have access to three X-ray images: one taken before the surgery, one immediately after the operation, and another from a follow-up appointment a couple of weeks later. A friend, who is employed at a different medical facility, consulted a radiologist regarding my follow-up X-ray and suggested that the K-wire might have shifted. In contrast, during my follow-up at the hospital where the initial procedure was conducted, there was no mention of this observation. Unfortunately, I wasn’t able to view my X-ray at that time, as I had a brief discussion with the surgeon while the nurse was removing my stitches, and I later requested a copy of the X-ray about a week after my visit. From my non-expert perspective, it does seem like there might be truth to my friend's assessment since the wire appears to be protruding more prominently from the bone in the follow-up image compared to the one taken right after the surgery. Additionally, the alignment of the bone looks less straight, although the positioning of my hand might have varied, as they had asked me to remove the support during the follow-up imaging. Currently, I have some concerns: - Has the K-wire shifted to an extent that could hinder the healing process? I’m anxious about the potential loss of mobility and functionality, as well as any visible deformities. - Does this situation indicate the need for another surgery, possibly replacing the K-wire with a plate and screws? I understand that the latter is a more invasive approach, yet it could provide superior outcomes with a reduced risk of complications. - How frequently do such occurrences happen, and what are the typical approaches taken in these cases? I am still receiving follow-up care, but I would greatly appreciate any professional perspectives and advice before my next appointment, as I have additional queries I intend to raise.

ArthritisCrohn's DiseaseInternal Medicine
Male25-34
1 hour ago