Vein Discoloration on the Underside of the Penis: Seeking Advice
Greetings, I’m a 24-year-old assigned male at birth. For the last six months, I have been on a regimen consisting of 50mg of Spironolactone as well as 2mg of Lupin-Estradiol. Approximately two weeks ago, after engaging in masturbation, I observed that a prominent vein located on the underside of my penis appeared darker and discolored. Although there is no associated pain or discomfort, I have noticed a significant reduction in the amount of semen produced during ejaculation, often resulting in little to no ejaculate at all. The discoloration of the vein persists, but I continue to experience no discomfort. Currently, I am unable to consult with my primary healthcare provider as I am working in a different province for the summer, and I have not yet visited a walk-in clinic for evaluation or advice.
Answers (1)

6/21/2025, 3:30:58 AM
OpenHealth AI
It's understandable to be concerned about changes in your body, especially when it comes to something as sensitive as a noticeable discoloration on the underside of the penis. Here are the main points:
- Vein discoloration and changes in ejaculation can be linked to various factors, including hormonal therapy, physical activity, or vascular changes.
- Since you're not experiencing pain or discomfort, this may suggest a lower risk of a serious issue, but monitoring your symptoms is important.
Explanation:
The discoloration you're noticing could be due to increased blood flow or structural changes in blood vessels, especially in the context of your use of Spironolactone and Estradiol. These medications can influence hormonal balances and potentially affect sexual function and semen production. Reduced semen volume may occur for several reasons, including hormonal changes affecting your prostate or seminal vesicles.
While the vein discoloration is not typically an immediate cause for alarm, it is important to keep an eye on any changes or additional symptoms that may develop.
Next Steps:
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Monitor Symptoms: Keep track of any changes in discoloration, the appearance of any new symptoms, or additional changes in ejaculation. Documenting this can be helpful.
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Hydration and Nutrition: Ensure you stay well-hydrated, as dehydration can impact semen production. A balanced diet rich in zinc (found in nuts, seeds, and legumes) can also support reproductive health.
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Physical Activity: Engage in moderate exercise, as this may help improve blood circulation. However, avoid activities that put pressure on the pelvis if you notice any discomfort.
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Plan for Evaluation: As soon as possible, try to schedule a visit to a healthcare provider or a local clinic to discuss your symptoms in detail. It's advisable to consult someone familiar with your medications and health history.
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Self-Care Practices: If you feel any tenderness or discomfort in the area during activities, take a break and allow time for recovery. Consider wearing supportive underwear to reduce any strain.
If you experience severe symptoms such as significant changes in pain, swelling, or any other concerning signs, prioritize seeking medical attention promptly. Let me know if you have any additional questions or need more specific advice!
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