Persistent Pelvic Pain with Chronic Endometritis: Seeking Guidance
Greetings, I’m looking for some insights regarding my current situation. After being diagnosed with chronic endometritis in 2022 during my IVF journey, a biopsy indicated the presence of plasma cells. I underwent a two-week treatment with two different antibiotics: doxycycline and metronidazole. Following a second biopsy, plasma cells were still observed. As a result, we conducted yet another biopsy, this time with DNA analysis and cultures, all of which returned negative results. Subsequently, I was prescribed steroids for the embryo transfer and through the first trimester, which culminated in a live birth and a healthy baby. Now, fast-forward to April, I began experiencing severe pelvic discomfort, prompting an ultrasound that revealed cysts and numerous calcifications in both my uterus and cervix. After revisiting my reproductive endocrinologist, we proceeded with a hysteroscopy to eliminate the calcifications and perform an additional biopsy. Unfortunately, plasma cells were still observed, indicating that chronic endometritis persists. We are planning yet another biopsy for DNA testing and cultures in hopes of detecting any bacterial presence this time. However, if the results are negative once more, I’m left wondering what the next steps might be. I continue to endure pelvic pain and a sensation of fullness. Should we be considering other conditions or conducting further examinations? I appreciate any advice on this matter!
Answers (1)
6/20/2025, 9:30:49 PM
OpenHealth AI
It sounds like you have been through a challenging medical journey with chronic endometritis and are seeking clarity regarding your ongoing pelvic pain and recent findings. Let’s summarize the main points and address your concerns:
Main Points:
- Chronic Endometritis and Plasma Cells: Despite treatments, the presence of plasma cells suggests persistent inflammation.
- Recent Findings: Cysts and calcifications were found in your uterus and cervix, and you've undergone several invasive procedures without conclusive results.
- Ongoing Symptoms: You are experiencing significant pelvic pain and discomfort.
Explanation:
Chronic endometritis can lead to various symptoms, including pelvic pain. The presence of plasma cells indicates ongoing inflammation, which may contribute to your discomfort. Cysts and calcifications can also be sources of pain and may complicate treatment approaches. When standard biopsies return negative, it doesn't eliminate the possibility of other underlying conditions that could be contributing to your symptoms.
Next Steps:
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Symptom Tracking: Keep a detailed diary of your symptoms. Note when the pain occurs, its intensity, and any activities that worsen or improve it. This information can be invaluable in understanding patterns and triggers.
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Reviewing Further Conditions: Discuss with your healthcare provider the possibility of exploring other conditions that could manifest in similar ways, such as:
- Adenomyosis
- Uterine fibroids
- Ovarian issues (like endometriomas)
- Other inflammatory conditions
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Consider Imaging Studies: Ask about advanced imaging techniques, such as MRI, to get a clearer view of the reproductive structures and identify any possible abnormalities that may not be visible on ultrasound.
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Evaluate Pain Management Options: Discuss pain management strategies with your healthcare team. This might include medications, physical therapy, or alternative therapies like acupuncture, depending on what you find comfortable.
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Holistic Support: Given the stress associated with chronic health issues, consider seeking support from a counselor or patient support group where you can share your experiences and coping strategies.
Lastly, remember that ongoing communication with your reproductive endocrinologist or a specialist in reproductive health is crucial as you navigate these symptoms and seek resolution. Please do not hesitate to reach out for further assistance!
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