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Are Sugar-Free Energy Drinks Linked to Low eGFR and Elevated Creatinine Levels?

6/20/2025, 3:20:29 PMMale25-34

My husband, who is 31 years old, weighs 240 pounds and stands at 5'11", has struggled with anxiety and depression in the past. Aside from that, he has no notable health complications and does not take any medications or supplements. He works night shifts and regularly consumes sugar-free energy drinks, particularly Monster. Recently, he noticed some unusual changes in his urine—namely, a strange odor and a darker, frothy appearance. Given that his father passed away due to liver failure, my husband is understandably concerned. His father had a history of Hepatitis C, which I believe was treated, yet he was also an alcoholic, a heavy smoker, and had untreated hypertension. I've attempted to reassure my husband that his health issues are not inherited. During a recent checkup, it was found that his urine contained a small amount of bilirubin and protein levels were at 30. Here are his results from yesterday: - **eGFR:** 66 mL/min/1.73 m² (Low; normal reference is 90) - **Creatinine:** 1.45 mg/dL (High; normal range is 0.6-1.1) - **AST:** 47 unit/L (High; normal range is 15-37) Last month, his eGFR was within the normal range, but his alkaline phosphate was slightly elevated at 129, and his ALT was borderline high as well. The rest of his results were acceptable. Next month, he plans to switch to daytime work, which I hope will reduce his reliance on energy drinks. Nonetheless, I'm anxious that potential damage might have already occurred. As far as I know, he typically consumes just one drink per night, although it’s possible it could be two. Thank you for your input.

LupusCrohn's DiseaseThyroid Disorders

Answers (1)

Cony

6/20/2025, 3:20:48 PM

OpenHealth AI

It’s understandable that you and your husband are feeling worried about his recent lab results and changes in his health. Based on the information provided, we can address his elevated creatinine levels, eGFR, and overall health implications related to energy drink consumption.

Main Points:

  • Current Findings: Your husband has elevated creatinine and AST levels, low eGFR, and changes in urine appearance, which could indicate kidney stress or potential liver issues.
  • Energy Drink Impact: Sugar-free energy drinks, particularly those high in caffeine and artificial additives, can sometimes contribute to kidney and liver stress, especially with excessive consumption.

Explanation:

The eGFR (estimated Glomerular Filtration Rate) gives insight into kidney function, with normal values typically above 90 mL/min. His current reading of 66 is concerning and suggests reduced kidney function. High creatinine levels further support potential kidney stress. Additionally, the presence of bilirubin and protein in the urine can indicate problems either with the kidneys or the liver.

Given your husband’s family history and the recent changes in his health, it’s essential to take these findings seriously. The fact that he plans to reduce his energy drink consumption as he transitions to daytime work is a positive step.

Next Steps:

  1. Limit Energy Drinks: Encourage your husband to significantly reduce or eliminate the consumption of sugar-free energy drinks. This could help alleviate any additional stress on his kidneys and liver.

  2. Hydrate Fluently: Ensure he drinks plenty of water throughout the day. Proper hydration can support kidney function and help dilute urine, potentially improving its appearance.

  3. Monitor Symptoms: Keep a close eye on any further changes in urine color, odor, or clarity. Note any other symptoms like fatigue, swelling, or changes in appetite.

  4. Maintain a Balanced Diet: Focus on a nutrient-rich diet that includes plenty of fruits, vegetables, lean proteins, and whole grains while reducing processed foods and high-sugar items.

  5. Follow-Up Testing: Plan to have follow-up lab tests to monitor kidney function (eGFR, creatinine) and liver enzymes (AST, ALT) as recommended by a healthcare provider.

  6. Health Routine: Encourage him to adopt a healthier lifestyle that includes regular exercise and stress-management techniques to support his overall well-being, especially considering his past struggles with anxiety and depression.

If any concerning symptoms arise, such as severe fatigue, nausea, vomiting, or significant changes in urine output, it would be important to seek medical attention sooner rather than later.

Remember, while family history can be alarming, many lifestyle adjustments can make a significant difference in health outcomes. Your support in following these steps can greatly help him feel better and manage his health more effectively.

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