OpenHealth Q&A

Get answered by medical professionals

Reduction of Hard Lymph Node After Biopsy: Seeking Insights

6/19/2025, 3:20:29 PMMale25-34

Greetings, I’m a 43-year-old man weighing 185 pounds, and generally I maintain good health. I indulge in alcoholic beverages only during special celebrations, and I smoke a cigar a couple of times each year. Additionally, I am quite active, engaging in exercise five days every week. For the past month, I have been dealing with a hard, immobile lymph node measuring 3 centimeters. Aside from this issue, I haven’t experienced any other noticeable symptoms, apart from a severe cough that I believe stemmed from a bout of COVID I contracted in May after exposure from my two-year-old daughter. I underwent an ultrasound and a comprehensive CT scan with contrast, which revealed no other lumps apart from the one located in my neck. Four days ago, I had a fine needle biopsy performed, and I observed that the lump appeared considerably smaller later that same day. According to the biopsy report, they removed 6 milliliters of serosanguineous fluid. This seems likely to explain the reduction in size of the lymph node. Is it common practice for such a volume of fluid to be extracted during this kind of biopsy? My understanding was that fine needle biopsies typically collect just small samples of tissue. What does the presence of this fluid within the lymph node signify—good news or cause for concern? I’m feeling quite anxious as I await the results and just need to focus on relaxing. I hope to receive that anticipated phone call within the next week. Any insights would be greatly appreciated!

Multiple SclerosisThyroid DisordersRheumatology

Answers (1)

Cony

6/19/2025, 3:20:47 PM

OpenHealth AI

It's understandable to feel anxious while waiting for biopsy results, especially given your experience with the hard lymph node and your current health status. Let's break down your situation and what it might mean.

Main Points:

  1. Volume of Fluid Extracted: It's not uncommon for a fine needle aspiration (FNA) to extract a significant amount of fluid if the lymph node is filled with it.
  2. Significance of the Fluid: The presence of serosanguineous fluid can indicate various conditions ranging from benign (like inflammation or infection) to more serious issues. The reduction in size of the lymph node after biopsy can be a positive sign, as it suggests that there may have been a lot of fluid within it.

Explanation:

  • Fine Needle Biopsy (FNA): This procedure is designed to extract either cells or fluid from lesions or lymph nodes. In your case, it sounds like the lymph node was likely reactive or inflamed due to an underlying issue (like a previous infection), which can sometimes lead to fluid accumulation. The amount removed (6 milliliters) is certainly substantial for FNA, indicating that there was a notable amount of fluid.

  • Potential Indications of the Fluid: The fluid could be a sign of a benign process, such as a reactive lymph node due to infection (like your prior COVID-19), or something else. The fact that you did not notice other symptoms is promising, but it’s important to await the results for a complete picture.

Next Steps:

  1. Stay Calm and Grounded: Try engaging in relaxing activities that you enjoy, such as light exercise or mindfulness practices. Managing your stress can help during this waiting period.

  2. Monitor Symptoms: Keep an eye on any changes in your body, such as new swelling, redness, fever, or an increase in cough. While it sounds like everything is stable, being aware can help you if circumstances change.

  3. Prepare for Your Results: Once you receive your results, jot down any questions or concerns you may have. This can help you clarify your understanding of the next steps in your care.

Remember that waiting for biopsy results can be an anxious time, but it’s also a step toward finding out what’s going on. Focus on maintaining your health and wellbeing during this time, and know that the information gathered will guide the next steps for your care. If you have further concerns or immediate symptoms arise, consider discussing them when you receive your results.

Related Questions

Understanding My Experience with Overdose-Related Symptoms and Behavior

25 years old, 165 cm tall, and weighing 70 kg. Summary: After sharing a complaint about my interactions with paramedics, I've taken a moment to reflect on their feedback and review the situation through the footage. I recognize that my conduct during those moments was inappropriate, and I am filled with remorse. Subsequently, I have retracted my complaint and am now seeking mental health support. I desire to clarify certain aspects since my medical records do not completely align with what I went through. Below, I detail my symptoms. Yesterday, I made a post on the AskDoctors forum, hoping for insights regarding my condition. The advice I received prompted a self-realization that had evaded me until now. Initially, I was outlining a grievance against paramedics who doubted the legitimacy of my seizures and accused me of feigning the experience. My response was not only disproportionate but also hostile—I yelled, wept, and labeled them as heartless. Such reactions were completely unwarranted and unjustifiable. Ultimately, I was physically stable, with vital signs indicating no critical issues; there were only temporary fluctuations in my blood work, which shouldn’t have raised alarms. I feel profound regret over my conduct during that encounter. Watching the footage incites feelings of self-disgust. I’ve decided to withdraw my complaints and am committed to mental health resources. I opted to delete my previous post since it contained sensitive information about my professional and educational background; I was worried it might provoke disciplinary action from my university, which I cherish as my career gives my life meaning. I admit to feeling cowardly in this respect. The initial reason for my inquiry was a desperate need for clarity about the symptoms I experienced, as my discharge documentation omits much of what transpired in the hospital and the subsequent three days. I greatly value the input I’ve received and hope to gather more perspectives. I fully acknowledge my wrongdoings and find my previous behavior abhorrent. I understand how challenging it is for emergency personnel to fulfill their duties when faced with such a situation. I’ve discussed with family and friends the importance of exercising discretion when contacting emergency services and ensuring it’s truly necessary. I regret taking up valuable resources that could have been reserved for individuals in genuine need of urgent care. My actions were shameful, not just for me but also for my colleagues who work in emergency services; I genuinely believe the clinicians should have distanced themselves from my case entirely. I've canceled my appointment with the neurologist, but I would genuinely appreciate insights from others on this subject. Could excessive doses of sertraline, propranolol, promethazine, and alcohol induce psychological seizures? Is it possible for these seizures to recur? Were my hallucinations indicative of some kind of psychosis? During the episodes, I saw hair-like formations everywhere and everything seemed to emit a blue glow. In the hospital, I consistently perceived doctors passing by. At home, the LED lights appeared to move, and I often caught glimpses of faces in my peripheral vision. There were also auditory experiences, such as hearing things that weren’t present, as confirmed by my friend. Initially at home, I was unaware I was having seizures, although I did hear police officers numbering them and acknowledging them as such. I had three episodes where I was placed in the recovery position. In my medical notes, I mentioned experiencing ten seizures throughout the night, though I can’t verify this. I was seemingly in a continuous cycle of them. I recall at least once drooling uncontrollably and my hands looked peculiar; on one occasion, I screamed when I regained consciousness due to an awkward hand position. I also experienced significant neck pain and discomfort in my feet. I know I fell twice while hospitalized; fortunately, my mother was there to catch me each time, so I avoided serious injury. I was never alone in the facility. Everything seemed to settle down after approximately three days, right around my third visit. I recall a persistent ache at the nape of my neck that left me feeling drowsy, often drifting in and out of consciousness and repeatedly asking for the time. It was a never-ending ordeal, and although I had little appetite, I did not vomit at all. Reflecting on this whole episode leaves me feeling as if it were entirely fabricated. I struggle to articulate it. Conversations about care options unfolded around me, yet I grasped little of what was being discussed. I often replied with “yes” or sought validation from my mother. I remember thinking it was remarkable that my mum had glasses with water in them; I even imagined one of my cats perched on my aunt’s shoulder. Overall, it felt akin to a terrifying drug experience. I do have videos capturing my behavior at home, though I cannot recall anything from the hospital. I often awakened with either my mother, aunt, or medical staff restraining me. Could it all stem from psychological causes? Is it possible that the medications led to a psychotic episode where I convinced myself I was experiencing seizures and on the brink of death? After they subsided, I felt like an automaton for weeks, plagued by involuntary muscle jerks—primarily in my legs and neck. I sincerely hope these symptoms do not return. I intend to avoid emergency care unless it’s absolutely necessary. I seek nothing more than to comprehend what transpired. Thank you for your thoughts.

Multiple SclerosisLupusThyroid Disorders
Male25-34
22 minutes ago

Understanding Recurrent Symptoms: Are They Histamine-Related?

Hello, health professionals, I am seeking your expertise regarding a variety of symptoms I have been experiencing intermittently over the years. While they appear linked, I'm having difficulty pinpointing their root cause. **Personal Summary:** - 27 years old, Female - Non-smoker (formerly vaped for about eight years, cessation initiated two years ago) - No diagnosed autoimmune conditions - Background of anxiety (which might exacerbate some symptoms, though it doesn't account for all) - Currently taking Flonase and a multivitamin **Skin Reactions:** - I've dealt with recurring itchy rashes and hive-like bumps since childhood. They manifest suddenly and usually resolve without intervention. - These rashes are often itchy, can be raised, and tend to appear sporadically without identifiable triggers. - Antihistamines provide consistent relief, leading me to suspect a role of histamines in these eruptions. - These episodes do not align with typical contact allergies or classic food allergies. - They can happen multiple times daily, and I've often dismissed them as merely anxiety-related rashes. - Sometimes the itching precedes the visible rash, while other instances present with a red, inflamed area that stirs inquiries about my well-being from others. **Foot Discomfort:** - Over the last few years, I’ve encountered severe itching on the soles of my feet. - These episodes typically include small pale or white spots with redness surrounding them, occasionally featuring a red center. - Itching intensity can be overwhelming, yet these lesions usually arise suddenly, - They frequently improve upon avoiding scratching and may resolve within a range of 30 minutes to two days. - The first episode was triggered after swimming in a freshwater lake, though I’ve also experienced it while wearing specific footwear like Crocs or boots, but not consistently. - Certain events coincide with my typical skin rash, hinting at a potential systemic condition rather than merely a localized issue. - The symptoms do not mirror those of warts, ringworm, or fungal infections. **Ear and Sinus Issues:** - Itchy ears have been a recurring issue for the past few years; I initially attributed it to overly aggressive cleaning with cotton swabs, which I realize is harmful. - I have a history of chronic sinus problems, including post-nasal drip and regular ear infections. - The inflammation appears to flare up sporadically rather than constantly. - Recently, I experienced a painful ear issue that began with what I thought was a pimple. The next day, my ear was swollen. After visiting a clinic, I was diagnosed with a double ear and sinus infection, treated with antibiotics. My pain persisted, leading to a follow-up with my primary care physician, who prescribed Flonase and noted ongoing nasal inflammation. Missing doses led to increased ear discomfort, prompting me to take Flonase more regularly. Unfortunately, a recent flare of swelling and discomfort in my ear led me to consider consulting an ENT specialist. **Gastrointestinal Symptoms:** - I was diagnosed with gastritis through an upper endoscopy procedure. - Testing for H. pylori returned negative. - I've since developed food sensitivities and gastrointestinal discomfort not previously experienced. - I saw significant improvement after removing gluten and dairy from my diet, with tests for celiac disease yielding negative results. - Symptoms tend to flare up in response to stress or specific food intake rather than being a constant presence. **Additional Context:** - A history of childhood asthma (now occurs infrequently) - Sensitivity to heat - Past instances of feeling lightheaded, resembling vasovagal symptoms, alongside vertigo - Symptoms across various systems often flare together, but not in every instance - While my anxiety can intensify symptoms, both antihistamines and diet modifications have had notable positive effects **My Inquiry:** While I don’t wish to self-diagnose, I'm curious if my range of symptoms might suggest: - Histamine intolerance - Mast-cell overactivity (not necessarily MCAS, but an increased reaction) - Physical or contact urticaria I'm primarily seeking: - Recommendations for a suitable specialist - Insight on whether this symptom pattern fits a recognized mechanism - A clearer understanding of what warning signs to be concerned about **Summary:** I contend with a long-standing pattern of episodic itchy rashes and hives, significant but transient foot itching along with bumps, persistent ear irritation coupled with sinus problems, and gastritis accompanied by food sensitivities that improved on an elimination diet. Antihistamines aid multiple symptoms. Could this suggest underlying histamine-related issues manifesting across multiple systems rather than in isolation?

FibromyalgiaCrohn's DiseaseThyroid Disorders
Male25-34
42 minutes ago

Seeking Guidance on Persistent Chest Discomfort After Extensive Testing

I'm a 43-year-old male, standing at 5'11" and weighing 180 pounds. My journey began around March to April of 2025 when, despite regularly hitting the gym four times a week, I was struck by severe chest pain along with frequent belching and a tight feeling in my diaphragm. At times, the pain became so intense that I feared it might be a heart attack. **Medical History:** In May 2019, I received a diagnosis of **PVS** and have since been under the care of a cardiac electrophysiologist. Upon experiencing these new symptoms, I consulted my EP, who conducted an EKG right then and set me up with a 7-day heart monitor. The results showed no irregularities. Subsequently, I was directed to a cardiologist, who carried out both a **stress test** and an **echocardiogram**, both of which yielded normal findings. Afterward, I returned to my primary care physician, who speculated that my gallbladder might be involved. An **ultrasound** was performed but revealed no issues. I then requested a **chest X-ray**, which also came back normal. My PCP then considered the possibility of a **hiatal hernia** and referred me to a gastroenterologist; unfortunately, that appointment took almost **five months** to materialize. In the meantime, my symptoms persisted, prompting me to cease weightlifting and switch my focus to **cardio and running**. Surprisingly, these activities didn’t exacerbate my symptoms, though the chest pain remained constant. When I finally saw the gastroenterologist, they suggested an **upper endoscopy**, which took another roughly three months to arrange. During this procedure, I was diagnosed with **Eosinophilic Esophagitis (EOE)**, a condition I had not previously experienced. The doctors also placed a pH monitoring device for acid reflux assessment, which indicated **no unusual acid exposure**. Following this, I began a treatment plan that included a swallowed steroid inhaler and an increased dosage of **omeprazole**. Sixty days later, I underwent another endoscopy, which showed that the EOE had largely resolved, with minimal residual symptoms. Unfortunately, my chest discomfort persisted without any improvement. It has now been about **a year** since these issues emerged, and I still have not found substantial relief. A recent chest MRI completed at a dedicated imaging center revealed no abnormalities. I entertained the idea of **costochondritis**, but again, the MRI did not support that hypothesis. The only minor relief I find comes from consciously pulling my shoulders back and expanding my chest. I continue to experience discomfort around my **diaphragm** and tenderness in the area of the **xiphoid process**. My PCP prescribed a steroid pack, which was somewhat beneficial for the pain but failed to alleviate the pressure or constant discomfort. At this juncture, I feel quite lost and uncertain about my next steps. I would greatly appreciate any insights or experiences from others who have faced similar issues. Additionally, if there are any physicians here willing to offer advice, I am open to traveling to find the answers or relief I'm desperately seeking.

FibromyalgiaThyroid DisordersInternal Medicine
Male25-34
1 hour ago

Prolonged Miscarriage: Over Four Weeks In

A 35-year-old woman managing Type 1 diabetes with an insulin pump has been experiencing a challenging period marked by a recent miscarriage. This occurred just shy of ten weeks into the pregnancy, following an extremely positive pregnancy test, although medical confirmation had not yet been obtained. The physical symptoms were quite severe, with substantial bleeding that included large tissue clumps and blood clots observed during a shower. The size of these clots was rather alarming, comparable to a fist, causing blockage in the drain. Initially, for the first three to four days, there was heavy bleeding, requiring three pads daily. After that, the situation gradually improved, and around a week ago, she reached a point where only a pantyliner might suffice. Despite the reduction, bleeding persisted intermittently, mainly noticeable upon wiping, with instances of no blood at all, leading to inconsistencies in her experience. Recently, she has been feeling bloated and has noticed a resurgence in bleeding, necessitating the use of pads twice daily. Additionally, she has been experiencing light cramps and has developed acne. A subsequent pregnancy test revealed continued positive results. Now, with over four weeks of bleeding, she reached out to her physician’s office. However, the response was not one of concern, suggesting that she could schedule a visit at her convenience if she felt the need. The cost of visiting a doctor or urgent care deters her from seeking immediate professional help unless absolutely warranted. Overall, she reports feeling generally well, but is seeking advice from others. Is there cause for alarm, or is it feasible to let things unfold naturally? Could this miscarriage have evolved into her menstrual cycle instead? Additionally, it's worth noting that she occasionally finds small blood clots on the toilet paper after wiping. Since the onset of this situation, she has abstained from sexual intercourse.

DiabetesEndocrinologyRheumatology
Male25-34
2 hours ago

Concerns After Gallbladder Surgery (Three Weeks Post-Op) - Is It an Infection?

Profile: - Age: 35 - Gender: Female - Height: 5 feet 4 inches - Weight: 160 pounds - Ethnicity: Asian Duration of Symptoms: Last Three Weeks Location: United States Recent Medical History: Nearly three weeks have passed since my gallbladder removal surgery. Over the last few days, I've noticed a small amount of unclear fluid coming from the incision. I just observed what seems to be pus oozing from the surgical site. Although there is slight tenderness when I move or touch the area, it isn't painful. Thankfully, I haven’t experienced any fever or chills, and there’s no unpleasant odor emanating from the wound. Should I continue to clean it with soap and water, or is it necessary for me to visit the emergency room for further evaluation?

Multiple SclerosisLupusInternal Medicine
Male25-34
2 hours ago