OpenHealth Q&A

Get answered by medical professionals

Understanding Swollen Lymph Nodes

6/19/2025, 10:20:25 AMMale25-34

Greetings, I’m a 28-year-old male. In February, I received a diagnosis of mononucleosis, which turned out to be quite severe. This led to a hospitalization and resulted in me developing sensitivities to certain medications, specifically NSAIDs. After my immunologist identified that these allergens were exacerbating my symptoms and once the virus had run its course, I initially began to feel better. However, recently, following a reduction in my medication as per my doctor’s advice, I have noticed that my lymph nodes have become swollen, causing persistent discomfort. Over the last 70 days or so, the lymph nodes in my neck, armpits, groin, and lower back have remained swollen. The situation has become so pronounced that my mother recently saw a noticeable lump on my neck. Additionally, my knees and other joints feel inflamed, making it difficult to walk comfortably. I am experiencing varying levels of post-exertional malaise (PEM) after even minor activities. I often feel an overwhelming itchiness and suffer from significant brain fog to the extent that I frequently forget what I intended to say. My sleep has been disrupted, often accompanied by night sweats, and despite maintaining my calorie intake, I'm unexpectedly losing weight due to having minimal physical activity. After consultation with my gastroenterologist, I have also begun to face symptoms of gastroesophageal reflux disease (GERD) and dyspepsia. Moreover, I've noticed numbness in my face, and this is just an overview of my daily experiences; there are additional sporadic symptoms, such as an unusual increase in my resting heart rate. Should I consider requesting referrals or tests from my doctor? I am feeling quite overwhelmed trying to understand the situation, especially since I had noticed some improvement before, yet my quality of life has significantly declined again even though the infection has resolved.

Multiple SclerosisLupusEndocrinology

Answers (1)

Cony

6/19/2025, 10:20:48 AM

OpenHealth AI

It sounds like you’re navigating a challenging combination of symptoms following your diagnosis of mononucleosis, and it's completely understandable to feel overwhelmed. Your swollen lymph nodes, joint inflammation, fatigue, sleep disturbances, and other symptoms suggest a complex situation that may benefit from further evaluation.

Explanation

Swollen lymph nodes can be a sign of various underlying conditions, especially after a viral infection like mononucleosis, which can sometimes lead to post-viral syndromes. Your reports of joint discomfort, PEM, brain fog, night sweats, and unintended weight loss, as well as your gastrointestinal issues, may point to an autoimmune condition or other underlying health issues that require thorough investigation.

Next Steps

  1. Document Symptoms: Keep a detailed journal of your symptoms, noting when they occur and their intensity. This can help in conversations with your healthcare team.

  2. Request Referrals and Tests:

    • Rheumatologist or Immunologist: Given your joint pain, fatigue, and potential autoimmune concerns, a referral to a specialist can provide insights into conditions like lupus or other rheumatological diseases.
    • Neurologist: If the numbness in your face continues, consider a referral to evaluate neurological conditions such as multiple sclerosis.
    • Gastroenterologist: Since you are experiencing GERD and dyspepsia, further tests may help rule out underlying causes.
  3. Communicate Your Concerns: When you meet with your healthcare providers, clearly express the full range of your symptoms, emotional impacts, and how they affect your daily life. This is crucial for comprehensive care.

  4. Focus on Self-Care:

    • Hydration: Stay well-hydrated, especially if you're dealing with fluctuating body weight and gastrointestinal discomfort.
    • Rest: Prioritize good sleep hygiene to help mitigate fatigue and brain fog. Consider creating a relaxing bedtime routine.
    • Nutrition: Work with a dietitian if losing weight remains a significant issue; they can help ensure you’re getting the nutrients you need even with reduced activity levels.
  5. Manage Stress: Techniques such as mindfulness, gentle yoga, or breathing exercises can be helpful in managing stress and improving your overall well-being amidst this challenging time.

Please remember that understanding your health is a journey, and it’s okay to seek clarity and support as you move forward. If your symptoms exacerbate or you experience any new concerning signs like severe pain or neurological issues, consider prompt medical attention. Take care, and ensure to advocate for yourself in your healthcare journey.

Related Questions

Navigating Health Concerns: A Young Woman's Plight with Chronic Migraines and Stress

To summarize a very complex situation, last spring in 2025 was exceptionally challenging for me. I faced overwhelming stressors, including family deaths, eviction, and my parents splitting up. This turmoil led to chest pains so severe that I had to visit the emergency room because I couldn’t breathe deeply without experiencing intense pain. The doctors attributed the issue to psychological causes, but I continued to suffer from pain and instances of fainting due to the stress, which worsened as yet another family member was diagnosed with cancer. My psychiatrist suggested medication, and I started on Lexapro and Concerta, which improved my condition somewhat, even though I remained fatigued and felt like I was merely surviving. By the end of August, I contracted a severe case of bronchitis that caused me to experience fevers even while doing laundry. It seemed I was verging on pneumonia, prompting the prescription of prednisone and other steroid medications. Thankfully, I began to recover quickly, but soon after, I was plagued by persistent headaches and an overwhelming sense of paranoia that someone was out to get me. After another emergency room visit, the physicians informed me that, although my symptoms—such as fever, intense pain, night sweats, sensitivity to light, ear pressure, and a stiff neck—were alarming, they were likely just severe migraines that should eventually fade. Unfortunately, they didn’t. I returned to urgent care for further treatment, received antibiotics, and was advised to consult a neurologist. While the antibiotics provided some relief, my symptoms intensified. My primary care physician eventually prescribed sumatriptan, a medication intended to alleviate migraine pain, but instead, it exacerbated the headache. For the next two to four weeks, I endured an exceptionally difficult time, facing numerous strange symptoms that felt worthy of immediate attention, yet each visit concluded with a migraine diagnosis and a waiting period for my neurology appointment. My frustrations pushed me to contemplate risky alternatives for relief, but I resisted, feeling utterly hopeless and unable to cope. I sought an ear, nose, and throat specialist to rule out sinus issues, which turned out to be fine. A painful spot under my jaw led me to suspect nerve involvement, and I visited the emergency room again due to experiencing stroke-like symptoms (including mild left arm weakness, extreme headache, and minor speech issues). Sadly, I was again told it was merely a headache, and the IV medications were ineffective. During my annual check-up, my primary care provider was unfamiliar with my ongoing issues but discovered an enlarged lymph node in the lower left side of my neck and a cyst on my thymus after conducting a soft tissue scan. She reassured me that there was no need for concern and suggested waiting for my neurology visit or getting my eyesight checked. Despite my yellower complexion, increasing stiffness, and joint pain, I accepted her recommendation. While I mentally adapted to the chronic pain, which was always present, it affected my ability to concentrate and engage in daily life. I tried consuming plenty of lemon juice and engaging in lymphatic drainage massages, which provided transient relief and halted my yellowing skin. Now, in the present, I've noticed a peculiar, raised red bump on the side of my foot. It’s hard, tender, and smaller than a dime, without any accompanying rash. It has persisted for a couple of weeks without causing pain while walking. Additionally, more lymph nodes in my neck have become swollen, I have experienced difficulty swallowing, and I occasionally choke on air. My lungs feel heavier with a diminished sense of smell, though I don't have the thick mucus typical of a cold. The headaches, however, are reemerging, sharper than before, which is a concerning development. Throughout all of this, my blood pressure has remained within a low yet stable range, and my blood tests and CT scans have shown no significant issues. I haven’t consumed anything excessively that might raise concern, including food or drugs. Am I truly facing a serious health crisis? Should I prioritize getting another appointment, or do I need to rush to urgent care? I'm scheduled to see the neurologist in about a month, and I'm wondering if I should ask my primary care provider for some preliminary tests like blood work or an MRI beforehand. If so, what specific questions should I prepare for my neurology visit? I believe the pain has a genuine physical basis, although my anxiety definitely amplifies the experience.

AsthmaMultiple SclerosisLupus
Male25-34
2 minutes ago

Inquiry Regarding Metronidazole Use for Recurrent Bacterial Vaginosis

I am a 32-year-old female, measuring 5 feet 5 inches tall and weighing 248 pounds. My current medications include Vyvanse at a dosage of 40mg, a medication for asthma, vitamin D, a 325mg iron supplement, and as of now, I am also taking amoxicillin to treat strep throat. I am about to begin using Metronidazole 0.75% Vaginal Gel, with a total of 70 grams available. The instructions indicate that I should administer 5 grams vaginally twice a day for seven days, followed by twice a week for a period of two months. During the initial treatment phase when I will apply the gel twice daily, I anticipate abstaining from sexual activity. However, once I transition to the twice-weekly application, is it permissible to engage in sexual intercourse? I would normally consult my physician about this matter, but she is currently unavailable, and the nurse is also out of the office, which is quite frustrating.

AsthmaArthritisMultiple Sclerosis
Male25-34
2 minutes ago

Concern Regarding Persistent Tongue Bump with White Coating

I am a 24-year-old male, standing at 190 cm tall and weighing 109 kg. For the past five weeks, I've experienced a peculiar issue on my tongue. Specifically, there's a noticeable bump on the right side near the tip, which I believe may have been developing over time, although I'm not entirely sure about that timeline. Recently, I've been troubled by an unusual sensation, including dryness, an odd taste, and a slight decrease in my sense of taste. Additionally, I've observed a white coating that is more pronounced on the aforementioned side of my tongue. The bump in question: - Does not cause any pain. - May have increased slightly in size over the weeks, though I'm uncertain. - Appears smooth with a pink surface, free of bleeding or ulceration. Given that this issue has persisted for over a month, I am feeling quite anxious and am concerned that it may indicate a serious problem. I have no significant medical history, but I confess that my dental hygiene has not been up to par, as I haven’t been brushing regularly. At this moment, I’m also under medication for H. pylori, known as Pylera, but this tongue concern predates my treatment. I am a non-smoker and am reaching out for any insights on this condition. Has anyone experienced something similar? Could this be a sign of irritation, infection, or something benign? I really appreciate any guidance you could provide. Thank you!

Thyroid DisordersInternal MedicineEndocrinology
Male25-34
12 minutes ago

Experiencing Clear Fluid from Ear with No Discomfort: Should I Wait for My Appointment?

I am a healthy 57-year-old female, weighing 120 pounds and standing 5 feet 5 inches tall. My daily medications include 100 mg of Losartan for effectively managed high blood pressure, 200 mg of Lyrica taken twice daily for post-herpetic neuralgia, 100 mg of Synthroid following treatment for thyroid cancer, and a combination hormone replacement therapy patch. Additionally, I take Zyrtec and Flonase every day to combat allergies. Since October, I have been dealing with persistent tinnitus in my right ear, accompanied by some pressure and a muffled sensation. Recently, I've noticed that when I speak, it feels akin to the sensation I experience when my ears clear during a flight after chewing gum—my voice sounds amplified in my head. I've scheduled an appointment with a physician's assistant in an ear, nose, and throat (ENT) office for the end of March due to my worries about the tinnitus and any potential hearing impairment. Yesterday, I noticed that my ear emitted a clear fluid. Thankfully, there was no associated pain. The fluid was somewhat thicker than water, completely odorless—unlike the unpleasant discharge I recall from my daughter's ear infections—and there was no sign of blood. Could this indicate a perforated eardrum? I suspect this might be the case, but can this occur without an underlying infection? Should I seek attention sooner than my appointment in March? I would prefer to avoid urgent care during flu season; however, if this situation is serious, I am prepared to take precautions and visit.

Thyroid DisordersInternal MedicineEndocrinology
Male25-34
52 minutes ago

Understanding the Increased Pain in My Foot While Reclining

At 30 years old, I am nearing the five-week mark since undergoing surgery on my metatarsals. I've encountered a troubling issue: I can’t seem to find comfort when lying down, whether it’s with my foot raised or lying flat. My pain level escalates to a severe 10 out of 10, unless my foot is making contact with the floor or I dangle my leg off the side of the bed so that my toes touch the ground. Is this situation typical for someone in my circumstances? Are there any suggestions that might assist me in getting a better night's sleep?

ArthritisMultiple SclerosisInternal Medicine
Male25-34
52 minutes ago