OpenHealth Q&A

Get answered by medical professionals

Deciphering Celiac Test Results

6/18/2025, 11:40:23 PMMale25-34

**Tissue Transglutaminase Antibodies, IgG** Concentration: <1.0 U/mL **Interpretation** - **<15.0:** No antibodies present - **≥ 15.0:** Antibodies detected **Tissue Transglutaminase Antibodies, IgA** Concentration: <1.0 U/mL **Interpretation** - **<15.0:** No antibodies present - **≥ 15.0:** Antibodies detected **Gliadin Deamidated Antibodies, IgA** Concentration: 4.0 U/mL **Interpretation** - **<15.0:** No antibodies present - **≥ 15.0:** Antibodies detected **Deamidated Gliadin Antibodies, IgG** Concentration: <1.0 U/mL **Interpretation** - **<15.0:** No antibodies present - **≥ 15.0:** Antibodies detected **IgA Level** Normal Range: 47 - 310 mg/dL Current Value: 321 mg/dL (Elevated)

Crohn's DiseaseInternal MedicineRheumatology

Answers (1)

Cony

6/18/2025, 11:40:40 PM

OpenHealth AI

Your test results suggest that you do not have the antibodies typically associated with celiac disease. Here’s a breakdown of your results:

  • Tissue Transglutaminase Antibodies IgG and IgA: Both are negative (<1.0 U/mL), indicating no presence of these antibodies.
  • Gliadin Deamidated Antibodies IgA: This test also shows a negative result (4.0 U/mL), well below the threshold of 15.0.
  • Deamidated Gliadin Antibodies IgG: This is negative as well (<1.0 U/mL).
  • IgA Level: Your IgA level is slightly elevated at 321 mg/dL, which is above the normal range.

Overall, the negative results for the celiac-specific antibodies strongly suggest that you do not have celiac disease. However, an elevated IgA level can indicate other underlying issues and may warrant further investigation.

Next Steps:

  1. Monitor Symptoms: Keep a note of any gastrointestinal symptoms or other health changes you might experience. This will help you identify any patterns or triggers.

  2. Diet Considerations: If you have noticed symptoms after consuming gluten, consider keeping a food diary. Even with negative celiac tests, some individuals may experience gluten sensitivity.

  3. Follow-Up Testing: Since your IgA level is elevated, consider discussing with a healthcare provider further tests or evaluation to explore other potential causes of this elevation, such as inflammation or infection.

  4. Regular Check-Ins: Schedule periodic evaluations to monitor your health and ensure that any changes in your IgA or symptoms are addressed promptly.

If you have specific concerns or if symptoms persist, it's important to communicate these with a healthcare provider for personalized advice and care.

Related Questions

Unusual Sensations and Clumsiness: Could It Be Drug-Related?

A 19-year-old female, standing at 5'10" and weighing 110 pounds, reveals a history of cocaine and Adderall misuse, though she is currently abstaining. Additionally, she takes Xanax sporadically for her panic attacks. For the past two weeks, she has been experiencing strange physical sensations, including numbness in both her hands and feet. Alongside this troubling symptom, she describes an increase in clumsiness, frequently bumping into furniture and tripping over her own feet—behavior that is markedly unlike her norm. Her body is now covered in bruises, likely a result of her newfound lack of coordination. Furthermore, she reports persistent headaches located at the back of her head. Her roommate, lacking medical knowledge, has speculated that her symptoms might indicate a brain tumor. This concern leads her to question if her past drug use could have potentially caused harm to her brain, especially since these sensations have arisen several months after her cessation of substance use. Is it plausible for these issues to emerge long after stopping the use of these drugs?

Multiple SclerosisLupusCrohn's Disease
Male25-34
16 minutes ago

Potential Vascular or Dermatological Concern?

Since the beginning of January, I've noticed a patch on my foot that appears either reddish or brownish. Initially, I didn’t pay much attention to it as it didn’t come with any discomfort—just some odd coloration. However, during my shower earlier today, I observed a new area of hyperpigmentation that seems to align with a vein on my foot. Despite these changes, I feel perfectly healthy and don’t have any symptoms to report. Yesterday, I engaged in a workout session where I used 20-pound dumbbells for the first time—I'm uncertain if that might be relevant to this situation. Could this possibly indicate venous pooling or be connected to capillary issues? I’m curious whether this discoloration will resolve on its own and if it warrants any concern.

Multiple SclerosisFibromyalgiaInternal Medicine
Male25-34
26 minutes ago

Concerns After Incorrect Methylprednisolone Dosing

As a 28-year-old male, I have been experiencing an unusual itchiness over my entire body for the past week, which has disrupted my sleep at night. Seeking relief, I reached out to my physician, who prescribed a 6-day course of methylprednisolone, with each pill containing 4 mg. In my haste, I overlooked the dosing instructions and inadvertently consumed all 6 pills at once on the first day (I felt perfectly normal throughout the day) during a meal, and then repeated the same mistake today by taking all 5 pills at once around noon, also with food. Following this, I started to develop flu-like symptoms including body aches, chills, abdominal discomfort, and mild nausea – all of which are recognized side effects of this medication. Should I be concerned enough to seek urgent care for hydration, or is it advisable to wait it out? I did speak with a pharmacist regarding my situation, and they appeared unconcerned; they simply advised me to continue taking the medication, but to adjust the dosing schedule to space it out over the day starting tomorrow. I'm looking for any additional insights or guidance on this matter.

Thyroid DisordersInternal MedicineEndocrinology
Male25-34
26 minutes ago

Am I to Blame for PID Treatment Issues?

Age: 29 Nationality: Indian American Height: 5'3" Weight: 128 lbs For the past year, I've been grappling with a pelvic infection. Initially, I was prescribed doxycycline for one week, which successfully eliminated the CT and Ureaplasma bacteria. In the following three months, I underwent testing on three different occasions and received negative results across the board. Despite that, I continued to deal with troubling symptoms, including an excessive watery discharge and persistent pelvic pain. Despite my pleas for treatment for pelvic inflammatory disease (PID), my requests were declined due to the negative lab results. Eventually, someone who was empathetic to my situation prescribed me a course of doxycycline for two weeks, along with a week’s supply of metronidazole. I also utilized an additional week of metronidazole that was repeatedly offered to me, even though my bacterial vaginosis tests continued to come back negative. During the PID treatment, I did engage in sexual activity, but both my partner and I tested negative for any infections. Could having sex during the treatment have hindered its effectiveness? I am still facing discomfort during intercourse, experience pain during ovulation (which is a new symptom for me), and occasionally feel strange pulling sensations in my pelvic area.

ArthritisCrohn's DiseaseInternal Medicine
Male25-34
55 minutes ago

Quick Remedies for Water in Ears

At 19 years old and weighing 150 pounds, I've encountered an all-too-familiar issue after a recent swim at a friend's pool. Throughout my childhood, I've frequently dealt with water getting trapped in my ears, and this occasion is no exception. Despite my attempts to remedy the situation—whether it's shaking my head vigorously, utilizing isopropyl alcohol, or employing the palm of my hand to create a suction effect—none of these methods have proven effective. As a result, I'm struggling to hear clearly in my right ear, which sounds incredibly muffled. It's so bad that if I want to muffle external sounds, I only need to block one ear, as the other one is completely obstructed. Honestly, I suspect that the palm vacuum method may have caused some irritation at the entrance of my ear canal, as I'm experiencing some pain. Feeling quite anxious about this situation, I've decided to visit a doctor soon. However, I'm hoping for some immediate advice or techniques to alleviate the problem more quickly.

Internal MedicineEndocrinology
Male25-34
1 hour ago