OpenHealth Q&A

Get answered by medical professionals

Questions Surrounding Urine Culture Findings

6/17/2025, 7:20:26 PMMale25-34

Hello everyone, I’m a 30-year-old female experiencing persistent bladder discomfort for approximately 15 years. Throughout this time, I’ve received treatment for numerous issues, including urinary tract infections, yeast infections, bacterial vaginosis, Ureaplasma, and pelvic pain. Currently, I’m undergoing pelvic floor physical therapy. Recently, my urine culture returned results indicating "Mixed urogenital flora Less than 10,000 colonies/mL." This is the second occurrence of similar findings. Despite this, I am experiencing symptoms typically associated with a urinary tract infection—such as foul-smelling urine, a burning sensation during urination, and a feeling of incomplete bladder emptying. I’ve read that mixed flora in urine cultures can suggest that a clean catch wasn't achieved. However, I made sure to cleanse myself, urinate a bit before filling the sample cup, and then proceed to collect the sample directly into the cup. What could this result imply? My healthcare provider suggests that there is no infection present. Should I be seeking a second opinion? Additionally, I have an upcoming appointment with a urologist in a few months to explore the possibility of interstitial cystitis, which I’ve been informed might often be regarded as a catch-all diagnosis.

Crohn's DiseaseInternal MedicineRheumatology

Answers (1)

Cony

6/17/2025, 7:20:43 PM

OpenHealth AI

It sounds like you're facing a challenging situation with longstanding bladder discomfort and recent urine culture findings. Your symptoms—such as burning during urination and a feeling of incomplete bladder emptying—can be quite distressing, especially given your history of persistent pelvic issues.

Main Points:

  1. Mixed Urogenital Flora Interpretation: The results showing "Mixed urogenital flora less than 10,000 colonies/mL" suggest that the sample might not reflect a significant urinary tract infection (UTI). Instead, it could indicate normal bacteria present, especially if the count is low.
  2. Symptoms & Next Steps: Despite the negative culture result, your symptoms warrant further investigation, particularly since they resemble those of a UTI and you've been experiencing discomfort long-term.
  3. Consultation & Follow-Up: Since you have a urologist appointment in a few months, continue preparations for that visit.

Explanation:

  • Mixed Flora in Urine: There are often normal bacteria that reside in the urinary tract and genitals. A culture showing mixed flora at this level typically suggests that it may not be caused by a singular infectious organism. It’s essential to consider other concerns, especially since you’re still having significant symptoms.
  • Possibility of Interstitial Cystitis (IC): Your upcoming appointment for possible IC is valuable. IC is often characterized by pelvic pain, urgency, and associated urinary issues but doesn’t always present with infection indicators.

Next Steps for You:

  1. Track Symptoms: Keep a detailed record of your symptoms—note their frequency, intensity, and any possible triggers. This information can help your healthcare provider in diagnosis.
  2. Explore Self-Care Practices: To alleviate discomfort in the meantime, consider:
    • Drinking plenty of water to dilute your urine.
    • Avoiding irritants (e.g., caffeine, alcohol, spicy foods).
    • Practicing pelvic floor exercises as guided in your physical therapy.
  3. Prepare for the Urology Appointment: Before your visit, compile your medical history, previous test results, and a list of all symptoms. Powerful communication will assist in better evaluation.
  4. Seek a Second Opinion if Needed: If you feel that your concerns aren’t being fully addressed by your current provider, seeking a second opinion particularly from a specialist can be beneficial. Ensure you communicate your pain points persistently during any consultations.

Your feelings about this condition are valid and you deserve clarity and relief from the discomfort. Let me know if you have any further specific questions!

Related Questions

Concerns About Breast Cancer

I'm a 42-year-old woman in good health, yet I'm currently grappling with uncertainty and numerous questions regarding my breast health. The wait to see a specialist feels like it's taking forever. Recently, I opted for a private ultrasound through HerScan, where they detected some abnormalities that were described as likely benign. The terminology they used included phrases such as "small cystic density" and "hypoechoic area" in comparison to breast tissue and soft tissues in the left axilla. As I navigate this anxious waiting period, I have some important questions: 1. In cases of metastatic breast cancer, is it typical for a breast tumor to be visible prior to any spread? Would this be detectable on a mammogram or an ultrasound? 2. I find myself in a confusing situation; after a normal mammogram nine months ago, my recent private ultrasound revealed abnormal findings. I have another mammogram and ultrasound scheduled for next week. However, I’m puzzled as to why the private facility couldn’t give a definitive answer about what they observed during the ultrasound. At every standard breast center I visited in the past, the technicians have always immediately communicated results such as "benign" or "cyst." This new place merely labeled it as "likely benign" and suggested a follow-up. Could this be due to the fact that it’s a private facility where they refrain from providing a diagnosis on the spot? 3. If next week’s tests come back clear and confirm the findings are benign, should I feel at ease accepting this conclusion? I understand that an MRI is considered the best method for dense breasts, yet I recognize I can’t compel a doctor to order it for me. Additionally, I am allergic to the contrast dye and suffer from significant claustrophobia, which complicates matters. This situation is weighing heavily on my mind, making it difficult to function normally. I can’t help but feel guilty for choosing to pay for a private scan, even though my anxiety propelled me into that decision. Here I am, caught between the fear of the unknown and the hope for reassurance.

FibromyalgiaCrohn's DiseaseThyroid Disorders
Male25-34
16 minutes ago

Expecting Mom at 7 Months: Doctor’s Concern Over Possible Blood Clot

A 35-year-old nonbinary individual, currently pregnant and measuring 5'6" at a weight of 232 lbs, has been steadily managing bipolar disorder with medications including Latuda, Cymbalta, and Lamictal over the past several years. Additionally, this person has been diagnosed with ankylosing spondylitis and has paused their biologic treatment during the course of the pregnancy, experiencing moderate symptoms by this point. Overall, the pregnancy so far has proceeded smoothly and without major complications. Earlier today, I had my routine check-up with my primary care physician, whom I hold in high regard and trust immensely. During the appointment, I brought up the calf cramps I’ve been experiencing and inquired about the possibility of incorporating magnesium supplements into my routine. After conducting a physical evaluation and observing my gait, the doctor expressed concern regarding the elevated resting heart rate and ongoing discomfort in my right calf, which intensifies when I flex my foot. Due to these symptoms, he suggested there may be a risk of blood clots and scheduled me for an ultrasound first thing tomorrow morning. In the event that a blood clot or DVT is discovered, what are the likely next steps? Should I expect a trip to the hospital? Is it advisable for my husband to accompany me, or would it be acceptable for me to drive myself? Additionally, I am curious about how significant my risk factors truly are—should I view this as a precaution and liability matter, or should I mentally brace myself for a potentially serious diagnosis? I appreciate any insights.

ArthritisMultiple SclerosisRheumatology
Male25-34
16 minutes ago

Experiencing Blurred Vision Post Chiropractic Treatment

I am a 22-year-old woman, weighing 160 pounds and standing at 5 feet 6 inches tall. After receiving a chiropractic adjustment earlier today, I noticed that my right eye became blurry. Initially, I attributed this feeling to having my face down on the treatment table for an extended period. Fortunately, the blurriness faded after roughly 20 minutes, though it felt longer than what I had anticipated. Perhaps I’m being overly cautious, but I came across information suggesting it could indicate a Vertebral Artery Dissection (VAD) or a Transient Ischemic Attack (TIA). This has left me feeling quite anxious and unsure about the next steps I should take.

ArthritisThyroid DisordersInternal Medicine
Male25-34
26 minutes ago

Persistent Urethral Discomfort

I am a 30-year-old male, standing at 5 feet 7 inches and weighing 185 pounds. On top of that, I have a history of irritable bowel syndrome (IBS) and I deal with both anxiety and depression. Currently, my medication regimen includes vilazodone and colestipol. Over the past several months, I've been experiencing a peculiar sensitivity in my urethra, accompanied by a growing urge to urinate more frequently than usual. This heightened awareness of discomfort seems to intensify particularly after engaging in sexual activities or during masturbation. Despite undergoing tests that have confirmed the absence of sexually transmitted infections, I have not found relief through antibiotics. My symptoms, while rather mild, make it challenging to articulate precisely what I am experiencing, leaving me uncertain about the implications of these sensations.

LupusCrohn's DiseaseInternal Medicine
Male25-34
36 minutes ago

Experiencing a Lengthy Period on Junel 1/20

A 24-year-old female, with no known health issues, stands at 5'4" and weighs 159 pounds. For nearly a decade, I have been using Junel 1/20 as my birth control method. Recently, during the final active week of my current pack, I noticed my menstrual cycle starting four days earlier than expected. At present, it continues, with fresh blood appearing when I wipe, alongside brown and dark red discharge found on my tampon. It seems like the flow might be diminishing. In five days, I will begin my next pack. Has anyone else dealt with an extended menstrual period while on hormonal contraceptives? — The discharge hasn't been substantial enough to completely fill a tampon; I typically change it every four hours, and it isn't saturated.

Internal MedicineEndocrinology
Male25-34
56 minutes ago