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Questions Surrounding Urine Culture Findings

6/17/2025, 7:20:26 PMMale25-34

Hello everyone, I’m a 30-year-old female experiencing persistent bladder discomfort for approximately 15 years. Throughout this time, I’ve received treatment for numerous issues, including urinary tract infections, yeast infections, bacterial vaginosis, Ureaplasma, and pelvic pain. Currently, I’m undergoing pelvic floor physical therapy. Recently, my urine culture returned results indicating "Mixed urogenital flora Less than 10,000 colonies/mL." This is the second occurrence of similar findings. Despite this, I am experiencing symptoms typically associated with a urinary tract infection—such as foul-smelling urine, a burning sensation during urination, and a feeling of incomplete bladder emptying. I’ve read that mixed flora in urine cultures can suggest that a clean catch wasn't achieved. However, I made sure to cleanse myself, urinate a bit before filling the sample cup, and then proceed to collect the sample directly into the cup. What could this result imply? My healthcare provider suggests that there is no infection present. Should I be seeking a second opinion? Additionally, I have an upcoming appointment with a urologist in a few months to explore the possibility of interstitial cystitis, which I’ve been informed might often be regarded as a catch-all diagnosis.

Crohn's DiseaseInternal MedicineRheumatology

Answers (1)

Cony

6/17/2025, 7:20:43 PM

OpenHealth AI

It sounds like you're facing a challenging situation with longstanding bladder discomfort and recent urine culture findings. Your symptoms—such as burning during urination and a feeling of incomplete bladder emptying—can be quite distressing, especially given your history of persistent pelvic issues.

Main Points:

  1. Mixed Urogenital Flora Interpretation: The results showing "Mixed urogenital flora less than 10,000 colonies/mL" suggest that the sample might not reflect a significant urinary tract infection (UTI). Instead, it could indicate normal bacteria present, especially if the count is low.
  2. Symptoms & Next Steps: Despite the negative culture result, your symptoms warrant further investigation, particularly since they resemble those of a UTI and you've been experiencing discomfort long-term.
  3. Consultation & Follow-Up: Since you have a urologist appointment in a few months, continue preparations for that visit.

Explanation:

  • Mixed Flora in Urine: There are often normal bacteria that reside in the urinary tract and genitals. A culture showing mixed flora at this level typically suggests that it may not be caused by a singular infectious organism. It’s essential to consider other concerns, especially since you’re still having significant symptoms.
  • Possibility of Interstitial Cystitis (IC): Your upcoming appointment for possible IC is valuable. IC is often characterized by pelvic pain, urgency, and associated urinary issues but doesn’t always present with infection indicators.

Next Steps for You:

  1. Track Symptoms: Keep a detailed record of your symptoms—note their frequency, intensity, and any possible triggers. This information can help your healthcare provider in diagnosis.
  2. Explore Self-Care Practices: To alleviate discomfort in the meantime, consider:
    • Drinking plenty of water to dilute your urine.
    • Avoiding irritants (e.g., caffeine, alcohol, spicy foods).
    • Practicing pelvic floor exercises as guided in your physical therapy.
  3. Prepare for the Urology Appointment: Before your visit, compile your medical history, previous test results, and a list of all symptoms. Powerful communication will assist in better evaluation.
  4. Seek a Second Opinion if Needed: If you feel that your concerns aren’t being fully addressed by your current provider, seeking a second opinion particularly from a specialist can be beneficial. Ensure you communicate your pain points persistently during any consultations.

Your feelings about this condition are valid and you deserve clarity and relief from the discomfort. Let me know if you have any further specific questions!

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