Concerns About Medication Regimen for Rheumatoid Arthritis
I’m a 28-year-old male, standing at 5 feet 8 inches and weighing 186 pounds. Recently, I was diagnosed with rheumatoid arthritis just two weeks ago, although I’ve been experiencing symptoms for approximately two months. I've begun treatment without utilizing any recreational drugs. Here’s my current medication list, which I feel may be excessive: - Leflunomide 20 mg: once daily - Hydroxychloroquine 200 mg: once daily - Methotrexate 25 mg: taking three pills every Saturday - Folic acid 5 mg: consuming two pills every Sunday - Prednisone 20 mg: I take one pill in the morning and half a pill at night for three weeks, with one dose already taken. After that, I plan to move to half a pill in the morning and half at night. - Omeprazole 20 mg: one pill each day before breakfast Initially, my regimen was more straightforward, consisting of: - Leflunomide 20 mg: once daily - Hydroxychloroquine 200 mg: two pills per day - Prednisone 20 mg: one pill during the day and one at night for four days, followed by one pill during the day and .75 at night for four days to adjust to the current dosing. At that time, I began to notice gradual improvements, although progress was slow. However, upon returning to my physician, adjustments were made to both the dosages and medications. I’m now questioning whether my current medication load is typical or if it indeed feels like too much. Thank you for your insights!
Answers (1)

6/16/2025, 4:30:56 AM
OpenHealth AI
It’s completely understandable to feel concerned about your medication regimen, especially after a recent diagnosis of rheumatoid arthritis (RA). Your treatment plan is aimed at managing symptoms and lowering inflammation, but it’s also natural to wonder if the number of medications is excessive.
Current Medication Overview
You’re currently taking a combination of:
- Leflunomide (20 mg daily): A DMARD (Disease-Modifying Anti-Rheumatic Drug) that helps to slow down the progression of RA.
- Hydroxychloroquine (200 mg daily): Often used to manage RA symptoms and provides anti-inflammatory effects.
- Methotrexate (25 mg weekly): Another key DMARD; it's important for controlling disease activity.
- Folic acid (5 mg weekly): Helps mitigate some side effects of methotrexate.
- Prednisone (adjusted dose): A corticosteroid that reduces inflammation and helps with flares.
- Omeprazole (20 mg daily): Used to protect your stomach, especially important when taking anti-inflammatory medications.
Understanding Your Concerns
Your current regimen is not uncommon for treating moderate to severe RA, which often requires a combination of medications to effectively manage symptoms. It’s common for treatment to evolve as doctors look for the best results, especially early on.
Next Steps
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Discuss with Your Doctor: It’s vital to express your concerns about the medication load to your physician, including how you’re feeling about taking several medications. They can clarify whether your regimen is appropriate for your disease severity and can help adjust it if indeed it feels excessive.
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Track Your Symptoms: Keep a detailed diary of your symptoms, medication doses, and any side effects you experience. This can help your doctor better understand your response to current treatments.
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Educate Yourself: Learn about each of your medications to understand their purpose, potential side effects, and the benefits they provide. Knowing more can empower you to make informed decisions.
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Lifestyle Considerations: Alongside medication, focus on anti-inflammatory diets, regular exercise, and stress management techniques like mindfulness, which can support overall health in managing RA.
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Regular Follow-ups: Ensure you're having regular follow-ups with your physician to evaluate your response to the treatment and make necessary adjustments.
Please feel reassured that you're taking a proactive approach to your health. It’s important to ensure you feel comfortable and informed about your treatment decisions. Let me know if you need more specific information about any of these medications or related concerns!
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