OpenHealth Q&A

Get answered by medical professionals

Upcoming Visit to Mayo Clinic

6/15/2025, 12:40:21 AMMale25-34

Next week, I will be heading to the Mayo Clinic for a consultation. I’m seeking some insights regarding the potential diagnoses I might be facing. As a 37-year-old woman, standing 5 feet 5 inches tall and weighing 130 pounds, I have been diagnosed with autoimmune gastritis, along with positive results for anti-parietal antibodies and high gastrin levels. Additionally, my lab results showed a positive ANA with cytoplasmic dots and a speckled pattern at a titer of 1:640. I frequently experience intense nausea accompanied by a sensation of tightness in my abdomen. During severe flare-ups, I endure profuse sweating, debilitating discomfort, and loss of control over my bladder and bowel functions. I have undergone two private stool tests, which, though somewhat contentious, revealed the presence of harmful bacteria. What could possibly be going on with my health? Is there any prospect for effective treatment? For symptom management, I have been prescribed Mirtazapine to alleviate nausea and Zofran as well. I’m perplexed about the ongoing issues with my stomach: Is it spasms, low motility, or perhaps accelerated motility? What steps should I take next?

NauseaFood IntoleranceIndigestion

Answers (1)

Cony

6/15/2025, 12:40:35 AM

OpenHealth AI

You are facing a complex situation surrounding your autoimmune gastritis and the symptoms you're experiencing, including the intense nausea and abdominal tightness. It’s understandable to feel perplexed, especially with the additional findings related to your autoimmune markers and stool tests.

Potential Issues and Insights

  1. Autoimmune Gastritis: This condition can lead to inflammation of the stomach lining, resulting in symptoms like nausea and abdominal discomfort. The high levels of gastrin indicate that your stomach may not be producing enough acid, which can further complicate digestion.

  2. Nausea and Abdomen Symptoms: Your description suggests several possibilities, including:

    • Spasms or Dysmotility: Abdominal tightness and nausea could be due to muscle spasms in the stomach or intestines.
    • Infections: The presence of harmful bacteria noted in your stool tests could contribute to nausea and general gastrointestinal distress.
  3. Positive ANA and Symptoms: The positive ANA with a speckled pattern could indicate an underlying autoimmune condition that may be affecting other body systems as well. This might help explain some systemic symptoms you could be experiencing.

Next Steps to Consider

  1. Symptom Diary: Keep a daily record of your symptoms, including when they occur, duration, and any potential triggers (foods, stressors, etc.). This information can provide valuable insight during your visit to the Mayo Clinic.

  2. Medication Effectiveness: Given that you're on Mirtazapine and Zofran, monitor how well these are managing your symptoms. Note any side effects or changes in your symptoms to discuss with your healthcare team.

  3. Dietary Adjustments: Consider a bland diet to help manage your nausea. Foods low in fat and fiber, like rice, bananas, and applesauce, may help. It may also be beneficial to track any foods that seem to worsen your symptoms.

  4. Hydration and Rest: Staying hydrated is crucial, especially if you're dealing with nausea. Focus on drinking clear fluids like water or herbal teas and ensure you get plenty of rest.

  5. Prepare for Your Consultation: Write down your questions and specific concerns about your symptoms and treatment options. Being prepared can help you get the most out of your visit.

Conclusion

While the situation feels challenging, there are various avenues for further investigation and management. Your upcoming consultation at the Mayo Clinic is a crucial step toward understanding your health better. Don’t hesitate to share all your symptoms and experiences with your healthcare team; they can guide you to effective treatment options tailored to your needs. Take care, and let me know if you need any further assistance!

Related Questions

Experiencing Unexpected Skin Pain Without Visible Cause

I have consulted my physician regarding my unusual symptoms, but she was unable to provide a clear diagnosis. The only possibility she mentioned was fibromyalgia, which she believes may not apply to me due to my age. Although blood tests were performed, everything appeared normal. I'm a 29-year-old female dealing with obesity and have been managing my weight for a long time, currently with the help of Wegovy. I was a smoker and vaper for several years but have quit these habits since last year. Occasionally, when I touch, scratch, or bump against areas like my shoulders, upper arms, thighs, and lower back, I experience severe pain beneath my skin that doesn’t correlate with any visible injury. There are no marks or rashes left behind afterwards. The sensation resembles that of a bruise or the sharp pain felt when one strikes their hip. There are moments when the pain is so intense that I involuntarily cry out, but it only lasts for a brief period of 5 to 10 seconds. The occurrences are erratic; some days I can touch or scratch these areas without any discomfort, while other days, the pain strikes unexpectedly. This has been a recurring issue for approximately five years now. I'm reaching out to see if anyone might have insights or suggestions about what this could indicate.

IBSFood IntoleranceInternal Medicine
Male25-34
1 hour ago

Dealing with Loperamide-Induced Constipation: Seeking Solutions

Warning: This discussion involves digestive health topics. I’m a 24-year-old woman, standing at 5’5” and weighing around 140 pounds. I don’t smoke and have been diagnosed with anxiety and depression. Recently, I was experiencing severe anxiety and dehydration due to some intense diarrhea, which prompted my doctor to prescribe loperamide. I took the initial dose two days ago and haven’t needed additional doses since then. However, now I find myself struggling with constipation and have yet to have a bowel movement. I’ve just started passing some gas, but still no stool. My anxiety persists, which is causing muscle tension and making it hard for me to breathe easily. To be honest, my eating and sleeping habits have been off due to the anxiety. My diet mainly consists of fruits, bread, rice crackers, beans, and jerky, and I only had a proper meal (tacos) today. I’ve also been trying melatonin for sleep, which is something new for me. I started with a 3 mg dose the first night, and I felt incredibly groggy the next day, so I reduced it to 1.5 mg the following night. I took both the loperamide and melatonin on the same evening. Unfortunately, my doctor is unreachable since the health clinic is closed over the weekend, leaving me without guidance. I’ve begun to experience some mild abdominal discomfort, but I think a proper bowel movement would alleviate that. I prefer to avoid over-the-counter remedies, as I’m concerned about jeopardizing my hydration, which has been quite the struggle. I’m wondering if anyone has suggestions for foods that might help, any stretches that could encourage movement, or if I should simply try to relax.

Stomach PainIndigestionConstipation
Male25-34
1 hour ago

Seeking Answers for Digestive Distress: Recommended Tests and Advice

I am a 34-year-old Caucasian female, standing at 165 centimeters tall and weighing 78 kilograms. On a daily basis, I take several medications: Prestance (5/5), Aerius, a hormonal contraceptive vaginal ring, and magnesium bisglycinate (365 mg). Occasionally, I also use Lexaurin (bromazepam) at a dosage of 0.75 mg every two or three weeks, primarily for anxiety and sleep disturbances, though I have not taken it in the last three weeks. Previously, I underwent multiple tests. Initial blood tests indicated a slight increase in amylase levels, which led to an abdominal ultrasound, yet nothing abnormal was detected. Both flexible sigmoidoscopy and a subsequent abdominal ultrasound were performed, revealing only hemorrhoids and an anal fissure. Throughout my life, I’ve grappled with digestive issues. Since childhood, I dealt with constipation, which ultimately resulted in hemorrhoids and my first anal fissure. To address this, I became conscious of my diet and utilized osmotic laxatives, which significantly improved my situation for many years, allowing me to have regular bowel movements without bleeding. However, approximately one year ago, I began experiencing unexpected episodes of diarrhea that can last between a couple of days to a week at a time. Mornings are particularly challenging, as I often experience loose stools, which eventually stabilize later in the day. During these episodes, I feel continually fatigued; after waking up, all I want is to return to bed, and merely completing my workday feels incredibly taxing. I also suffer from persistent nausea without vomiting, and this typically follows a pattern of ten days of normal or firmer stools followed by three days of diarrhea. Thankfully, I managed to avoid any diarrhea for over two months and even found myself needing to use Miralax occasionally. However, this past Wednesday, I awoke to an upset stomach once again. My meals consist of homemade food, which I ensure is not overly greasy or heavy, avoiding fast food and excessive sweets altogether. My overall daily functioning is severely impacted by the fatigue and frequent headaches I experience. Although I don’t encounter much abdominal pain, I do feel cramping in the lower central abdomen along with considerable gas and rumbling. I have scheduled an appointment with my general practitioner for Monday, though I find her approach somewhat passive; she tends to follow my requests rather than take the lead. What diagnostic tests should I consider requesting? While I am open to the possibility of upper endoscopy, a full colonoscopy seems daunting due to my anal fissure. I would greatly appreciate any insights regarding what might be happening. I understand it’s difficult to provide specific answers, but any guidance would be immensely appreciated!

DiarrheaIndigestionConstipation
Male25-34
3 hours ago

Could This Be IBS or Something Else?

Greetings! I’m a 27-year-old male, standing at 172 cm and of European descent, currently using Iqos. My medical troubles began roughly four months ago, around October 5, 2025. Initially, I experienced intense back pain lasting for two days, which I recognized as kidney stone pain. To alleviate this discomfort, I took NSAIDs, predominantly Metamizole-Natrium. Afterward, I visited urgent care, where I was given Diclofenac and Monural, an antibiotic for urinary tract infections. I took one of each at night. **A couple of days later, I started experiencing several troubling symptoms:** - Frequent diarrhea (4-5 times a day, often watery) - Significant gas and belching - Persistent nausea that greeted me each morning, sometimes relieved by eating - A general sense of malaise - A loss of 5 kg (I dropped from 63 kg) because I lacked appetite, especially under stress. These symptoms developed quickly and intensified through October, fluctuating over time. Blood tests showed no abnormalities, with normal CRP levels. Then in November, I underwent a colonoscopy and gastroscopy. - I had three very small erosions, about 1-2 mm, in the terminal ileum, but no signs of inflammation. Histology revealed no pathological issues, all was well. - There was one small erosion in the sigmoid colon, with minor inflammation around it. Histological findings indicated small infiltration in the lamina propria but no chronic signs, leading to a diagnosis suggesting a high likelihood of infection. - The areas were healing, with fibrin present. The rest of my colon appeared healthy. The doctor attributed the ulcers to NSAID-induced damage. I was later diagnosed with LA-A GERD. Due to my anxiety about health, I spent the month consumed by fears of complications such as colon cancer, PC, or Crohn's disease. I finally found some relief and felt symptom-free for the subsequent two weeks. However, in December the troubles resurfaced, though to a lesser degree, with occasional loose stools—2-3 times for a few days— and lingering gas. My anxiety about Crohn's returned, and I mistakenly took Algopyrin Complex, which triggered additional stress. **In December, my primary worries included:** - Loose stools resembling Bristol type 5-6, mainly occurring once each morning - Excessive gas often felt trapped in my rectum - My weight stabilized at 62 kg **I underwent various tests:** - Negative results for Giardia and E. coli - Negative FIT tests - Negative MRI (everything appeared normal) - Negative MRE (all normal) - Calprotectin level measured at 18.7 - I was found to have low levels of B9 and Vitamin D, with B12 at 320 and LDL at 5.9 **Moving into January:** - I only had one bowel movement each morning, sometimes loose, but mostly firm in the past three weeks (Bristol 4), compared to my usual Bristol 2. - After meals, I often felt gas building in my rectum, sometimes getting stuck before eventually releasing. This gas, thankfully, rarely had an odor. - Mornings have been troublesome, as I needed to pass gas 2-4 times, and in bed at night, I felt bloated with gas movements. **What I have observed:** - No signs of blood in my stools - No pain - No nocturnal symptoms affecting my sleep - No extraintestinal symptoms - My weight has stabilized without additional loss after recovering some weight Overall, I feel fine, yet the worry about my condition persists in my mind. Previously, I would have bowel movements twice weekly, with little to no gas. It baffles me that I often wake up feeling this uncomfortable. My primary concern is whether I should be worried about Crohn's disease (which occupies my thoughts constantly) or if my symptoms might stem solely from anxiety. Currently, I'm taking the following medications and supplements: - Itopride (doctor suggested it for motility issues) - L-Glutamine - Curcumin - A B-complex supplement - Ashwagandha - I briefly tried rifaximin for three days, but it did not yield significant changes. - I had also experimented with antacids previously, though they proved ineffective. Thank you for your assistance in advance!

IBSIndigestionConstipation
Male25-34
8 hours ago

Interpreting My Gastrointestinal Discomfort

A 26-year-old female, weighing 155 pounds, has a background of experiencing gastroesophageal reflux disease (GERD) and anxiety. She has been using marijuana for several years and is currently taking venlafaxine at a dosage of 150 mg each day. Residing in the Midwest USA, she identifies as white. On January 20th, she experienced what she initially believed to be a low blood sugar episode. Due to being preoccupied and busy, she had not consumed much food throughout the day. Consequently, she felt lightheaded, nauseated, pale, and was sweating. To alleviate these symptoms, she consumed around 60 to 80 grams of carbohydrates once they began, but it took roughly 2.5 hours for her to start feeling better. The following day, she faced additional discomforts including nausea, heartburn, body aches, trembling with chills and sweats, along with diarrhea. These symptoms persisted for a few days. By January 23rd, she consulted urgent care, where the medical team suspected a stomach virus and advised her to let it run its course. Regrettably, her stomach has not returned to its normal state since that incident. She has been experiencing occasional heartburn and indigestion reminiscent of her previous severe GERD episodes. Additionally, she is suffering from lower abdominal cramps, particularly triggered by consuming items like popcorn or spicy foods, which feels akin to irritable bowel syndrome (IBS) symptoms. During the height of her symptoms on January 20th, she ceased smoking. She partook in smoking a few times between January 24th and 28th, without noticing any changes in her symptoms – positive or negative – and has refrained from smoking since then. It is worth noting that she has not experienced any vomiting or severe abdominal pain typically associated with cannabinoid hyperemesis syndrome (CHS). Are her symptoms indicative of CHS? She intends to abstain from smoking yet seeks clarity on the underlying cause of her discomfort. She has read about post-viral IBS and is curious if the suspected stomach virus has reignited her GERD, which had been stable for several years.

BloatingIndigestionAcid Reflux
Male25-34
23 hours ago