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Dystonic Reaction in a Young Patient

4/23/2025, 3:40:25 PMMale25-34

I have a 9-year-old daughter weighing 69 pounds who has been diagnosed with generalized epilepsy. Recently, she was given clozapine to help manage her seizures during an illness. Unfortunately, this was her first experience with this particular medication, and she has been experiencing a dystonic reaction as a side effect. Initially, her condition was serious enough to warrant hospitalization due to respiratory issues. While in the hospital, she responded positively to IV Benadryl during her episodes. However, we are now on the fourth day since returning home, and she has had to call for paramedics again, although she was released from the emergency room. Medical staff believe the medication is gradually leaving her system. Today, she is suffering from severe spasms affecting her neck and jaw, and I am struggling to administer Benadryl. Is it advisable to seek hospitalization once more, or can this situation be managed safely at home?

DiabetesMultiple SclerosisCOPD

Answers (1)

Cony

4/23/2025, 3:40:48 PM

OpenHealth AI

It sounds like your daughter is experiencing a concerning and distressing situation related to the dystonic reaction from clozapine. This reaction can cause severe muscle spasms and discomfort, particularly in the neck and jaw area. Given her previous hospitalization and the current severity of her symptoms, it’s crucial to prioritize her safety and well-being.

Key Points:

  1. Dystonic Reactions Can Be Serious: Dystonic reactions can sometimes escalate quickly and may require immediate medical attention, especially if the symptoms are severe.
  2. Past Response to Treatment: Your daughter had a positive response to IV Benadryl while in the hospital, which indicates that antihistamines may help manage her symptoms.

Recommended Actions:

  1. Seek Medical Attention: Given the severity of your daughter's spasms and the past need for hospitalization, it is advisable to seek immediate medical help. If her spasms are severe and affecting her ability to breathe or speak, or if you are unable to administer Benadryl effectively, it's crucial to call paramedics or go to the nearest emergency room.

  2. Administer Benadryl if Safe: If the paramedics are not immediately available and you can safely give her Benadryl (based on dosing recommendations for her weight), you might consider doing so while waiting for help. However, don't delay calling for immediate assistance if her symptoms appear intense.

  3. Document Symptoms: Keep a record of her symptoms, including the frequency and duration of the spasms and any other associated symptoms. This can provide valuable information to healthcare professionals.

  4. Monitor Temperature and Breathing: Pay attention to her respiratory status and temperature. If she shows any signs of increased difficulty breathing, confusion, or other alarming changes, this increases the urgency of seeking help.

Conclusion:

In summary, due to the recurrence of severe spasms, it’s best to err on the side of caution and seek medical help again. Your daughter’s safety is the top priority, so don’t hesitate to call for assistance if her condition worsens.

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