Managing Nausea During Pregnancy with SSRIs
I’m a 31-year-old woman weighing approximately 9 stone and standing 5 feet 6 inches tall. My background is White British, and I do not smoke. With my first pregnancy, I experienced extreme nausea for the initial 14 to 16 weeks, making it extremely difficult to function day-to-day. As my husband and I begin to plan for our second child, I have been exploring options for anti-nausea medications. However, I’ve come across warnings stating that these medications are not compatible with selective serotonin reuptake inhibitors (SSRIs) like the Citalopram 20mg I am currently taking. While I believe it’s essential to maintain my SSRIs throughout my pregnancy, I am considering a gradual reduction leading up to it, with the intention of resuming once I give birth. I’m aware that Citalopram is generally regarded as safe during pregnancy, but I am struggling to identify any anti-nausea medications that would be safe to use alongside it once I conceive. If anyone has any recommendations or advice, I would greatly appreciate it, as I’ve found that various home remedies I’ve attempted have not provided sufficient relief. Thank you!
Answers (1)

4/23/2025, 10:10:39 AM
OpenHealth AI
It's understandable to feel overwhelmed about managing nausea during pregnancy, especially while considering the use of SSRIs like Citalopram. The good news is that there are safe approaches to take for nausea management without compromising your mental health treatment.
Key Points:
- Nausea in pregnancy is quite common, especially in the first trimester, and SSRIs like Citalopram can be safely continued throughout pregnancy for those who need them.
- There are anti-nausea options that are considered safe to use with Citalopram, and some non-medication strategies might help alleviate your nausea.
Explanation:
Medications for nausea, such as certain antihistamines (for example, doxylamine) and vitamin B6 supplements, are often recommended and have been established as safe during pregnancy. Your concern about SSRIs is valid, as some medications can interact with each other. However, SSRIs themselves, including Citalopram, are generally deemed safe during pregnancy, but it’s essential to consult healthcare advice specific to your needs.
Next Steps:
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Discuss with your healthcare provider about the possibility of integrating anti-nausea medications that are safe with Citalopram, like doxylamine or vitamin B6. They can help determine the best options tailored for you.
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Monitor your symptoms and keep a record of any changes in your nausea and overall health as you prepare for pregnancy. This information can be helpful in discussions with your healthcare provider.
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Explore non-medication strategies such as:
- Eating small, frequent meals that are rich in carbohydrates (like crackers or toast).
- Staying hydrated, sipping on clear fluids if solid food feels challenging.
- Trying ginger tea or ginger candies, which have shown promise in alleviating nausea for some women.
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Consider lifestyle changes that promote relaxation and stress relief, such as gentle exercise, prenatal yoga, or deep breathing exercises, which may help reduce nausea as well.
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Prepare for pregnancy: If you find that extreme nausea becomes overwhelming again, have a plan in place. Knowing you can safely take certain medications or have support systems can provide you with peace of mind.
If you need further support or if you experience any concerns during your pregnancy journey, don't hesitate to reach out. Emotional well-being is just as important as physical health during this time. Consider reaching out to a healthcare professional who specializes in maternal mental health for additional advice tailored to your specific situation.
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