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Understanding AST/ALT Ratio

4/4/2025, 5:50:20 PMMale25-34

Hello everyone, I’m a 48-year-old woman. My latest blood test results indicate that my AST level is 22 and my ALT level is 18, which are both deemed normal. Nevertheless, upon researching, I discovered that my AST/ALT ratio is 1.2, which some sources suggest could indicate a risk for cirrhosis. This leaves me wondering whether that’s a valid concern, given that other information I found states that if both enzyme levels are normal, the ratio may not be significant. Additionally, all other aspects of my comprehensive metabolic panel (CMP) were also normal. I appreciate any insights you can provide on this matter.

AgingInternal MedicinePreventive Medicine

Answers (1)

Cony

4/4/2025, 5:50:37 PM

OpenHealth AI

Your AST level of 22 and ALT level of 18 are indeed within the normal range, which is an encouraging sign. While your AST/ALT ratio of 1.2 may raise some questions, especially with some sources suggesting connections to liver issues like cirrhosis, your overall normal liver enzyme levels imply that there isn't an immediate cause for concern.

Explanation

AST (aspartate aminotransferase) and ALT (alanine aminotransferase) are enzymes that help assess liver health. In general, when both enzyme levels are normal, the specific ratio often holds less significance. The AST/ALT ratio can suggest certain liver conditions when elevated, particularly if there are concerning symptoms or other abnormal lab results.

Next Steps

  1. Monitor Regularly: It’s a good idea to continue regular health check-ups and liver function tests as recommended by your healthcare provider. This helps ensure that your liver health remains stable.

  2. Lifestyle Factors: Focus on maintaining a healthy lifestyle, which includes:

    • Eating a balanced diet rich in fruits, vegetables, and whole grains.
    • Staying hydrated and limiting alcohol intake.
    • Engaging in regular physical activity.
  3. Symptom Watch: Pay attention to any unusual symptoms such as fatigue, jaundice (yellowing of the skin or eyes), or abdominal pain. If these arise, consider reaching out for further investigation.

  4. Stay Informed: If you have concerns about your liver health or specific risk factors (such as family history, obesity, or heavy alcohol use), consider discussing them with a healthcare professional.

In summary, while your AST/ALT ratio may raise questions, your normal enzyme levels suggest that there is currently no significant risk. Maintaining a healthy lifestyle and monitoring your health is the best approach moving forward. If you have any specific questions or feel uncertain, feel free to ask!

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