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Understanding High Iron Levels: My Concerns About Hemochromatosis

4/4/2025, 5:20:22 PMMale25-34

Profile: 29-year-old male, residing in the US, weighing 165 lbs and standing 6 feet tall. Currently prescribed gabapentin at 300 mg per day for restless legs syndrome, and omeprazole for gastroesophageal reflux disease (GERD). Greetings, everybody. Approximately nine months ago, I underwent blood tests to assess my iron levels in the context of my restless leg issues. The results indicated elevated levels of iron and iron saturation. I should mention that I previously conducted a 23andMe genetic test, which showed no signs of the hemochromatosis gene. Here are my lab results from nine months ago: - Total Iron: 242 mcg/dL - Iron Binding Capacity: 372 mcg/dL - Saturation: 65% - Ferritin: 102 ng/mL More recently, I had another round of tests, and these were the findings: - Total Iron: 204 mcg/dL - Iron Binding Capacity: 331 mcg/dL - Saturation: 62% - Ferritin: 152 ng/mL I can’t help but wonder if my alcohol consumption is a contributing factor. While I have significantly reduced my intake, I still indulge in about eight beers on weekends or every other weekend. For reference, my liver test results from nine months ago were as follows: - AST: 28 U/L - ALT: 45 U/L Additionally, I have been referred to a hematologist for a more in-depth evaluation regarding my iron levels. I appreciate any insights or advice you can provide. Thanks!

AgingWellnessFamily Medicine

Answers (1)

Cony

4/4/2025, 5:20:38 PM

OpenHealth AI

Your concerns about elevated iron levels and their potential connection to hemochromatosis are valid, especially given your history and the recent lab results.

Main Points

  1. Your iron levels are elevated, but your genetic testing for hemochromatosis was negative.
  2. Alcohol consumption can contribute to elevated iron levels and liver function.
  3. Referral to a hematologist is a valuable next step for further evaluation.

Explanation

Elevated iron levels (as indicated by your tests) can result from multiple factors. Hemochromatosis is a genetic disorder that can lead to excessive iron accumulation, but since your 23andMe results are negative for the gene, it might be less likely in your case. Your ferritin levels have increased, suggesting that your body is storing more iron. It’s good that you are being referred to a hematologist, as they will provide more specialized insight into your iron metabolism and any necessary testing.

Next Steps

  1. Document Your Symptoms: Keep a log of any symptoms you may experience, such as fatigue, joint pain, or abdominal discomfort, since they can help the hematologist in their evaluation.

  2. Manage Alcohol Intake: While you’ve cut back, consider further reducing your alcohol consumption. Alcohol can promote iron absorption and increase liver stress. Aiming for moderation or abstaining for a period could be beneficial.

  3. Iron-Modulating Diet: Focus on a balanced diet that is lower in iron-rich foods, particularly red meat and shellfish, while increasing consumption of fruits and vegetables which can aid your overall health.

  4. Monitor Liver Function: Continue to keep an eye on your liver function tests. If you see any significant variations, note those for your hematologist discussion.

  5. Follow Up After Hematologist Visit: After your appointment, review any recommendations for managing your iron levels and follow them closely.

Make sure to keep an open dialogue with your healthcare providers about your concerns and test results. You're taking positive steps by seeking further evaluation, so continue to stay informed and proactive regarding your health. If other symptoms arise or you have more concerns, consider addressing them sooner.

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